ID   MVP_CMVS                Reviewed;         279 AA.
AC   Q66134;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Movement protein;
DE            Short=MP;
DE   AltName: Full=Protein 3A;
GN   ORFNames=ORF3a;
OS   Cucumber mosaic virus (strain S) (CMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Bromoviridae; Cucumovirus.
OX   NCBI_TaxID=117126;
OH   NCBI_TaxID=3659; Cucumis sativus (Cucumber).
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH   NCBI_TaxID=3562; Spinacia oleracea (Spinach).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8614989; DOI=10.1006/viro.1996.0048;
RA   Cooper B., Schmitz I., Rao A.L., Beachy R.N., Dodds J.A.;
RT   "Cell-to-cell transport of movement-defective cucumber mosaic and tobacco
RT   mosaic viruses in transgenic plants expressing heterologous movement
RT   protein genes.";
RL   Virology 216:208-213(1996).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Acts by forming a tubular structure at the host
CC       plasmodesmata, enlarging it enough to allow free passage of virion
CC       capsids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000250}. Note=Assembles into long tubular structures at the
CC       surface of the infected protoplast. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cucumovirus movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; U37227; AAB02147.1; -; Genomic_RNA.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000603; MPV.
DR   Pfam; PF00803; 3A; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Transport; Viral movement protein.
FT   CHAIN           1..279
FT                   /note="Movement protein"
FT                   /id="PRO_0000083248"
FT   REGION          256..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..279
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   279 AA;  30342 MW;  B30B1BEBB0E11880 CRC64;
     MAFQGTSRTL TQQSSAASSD DLQKILFSPD AIKKMATECD LGRHHWMRAD NAISVRPLVP
     QVTSNNLLSF FKSGYDAGEL RSKGYMSVPQ VLCAVTRTVS TDAEGSLKIY LADLGDKELS
     PIDGQCVTLH NHELPALISF QPTYDCPMEL VANRHRCFAV VVERHGYIGY GGTTASVCSN
     WQAQFSSKNN NYTHAAAGKT LVLPYNRLAE HSKPSAVARL LKSQLNNVSS SRYLLPNVAL
     NQNASGHESE ILNESPPIAI GSPSASRNNS FRSQVVNGL