ID   MVP_CMVY                Reviewed;         279 AA.
AC   P18028; P89528;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Movement protein;
DE            Short=MP;
DE   AltName: Full=Protein 3A;
GN   ORFNames=ORF3a;
OS   Cucumber mosaic virus (strain Y) (CMV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Bromoviridae; Cucumovirus.
OX   NCBI_TaxID=12312;
OH   NCBI_TaxID=3659; Cucumis sativus (Cucumber).
OH   NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Nitta N., Masuta C., Kuwata S., Takanami Y.;
RT   "Comparative studies on the nucleotide sequence of cucumber mosaic virus
RT   RNA3 between Y strain and Q strain.";
RL   Nihon Shokubutsu Byori Gakkaiho 54:516-522(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=9032362; DOI=10.1128/jvi.71.3.2270-2276.1997;
RA   Nagano H., Okuno T., Mise K., Furusawa I.;
RT   "Deletion of the C-terminal 33 amino acids of cucumber mosaic virus
RT   movement protein enables a chimeric brome mosaic virus to move from cell to
RT   cell.";
RL   J. Virol. 71:2270-2276(1997).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Acts by forming a tubular structure at the host
CC       plasmodesmata, enlarging it enough to allow free passage of virion
CC       capsids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC       {ECO:0000250}. Note=Assembles into long tubular structures at the
CC       surface of the infected protoplast. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cucumovirus movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; M57602; AAA46419.1; -; Genomic_RNA.
DR   EMBL; D12499; BAA02060.1; -; Genomic_RNA.
DR   EMBL; D83958; BAA12151.1; -; Genomic_RNA.
DR   PIR; JA0096; P3VXY1.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000603; MPV.
DR   Pfam; PF00803; 3A; 1.
PE   3: Inferred from homology;
KW   Host cell junction; Transport; Viral movement protein.
FT   CHAIN           1..279
FT                   /note="Movement protein"
FT                   /id="PRO_0000083250"
FT   REGION          246..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        257..271
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        77
FT                   /note="V -> A (in Ref. 2; BAA12151)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   279 AA;  30475 MW;  969F27B75012C820 CRC64;
     MAFQGTSRTL TQQSSAATSD DLQKILFSPE AIKKMATECD LGRHHWMRAD NAISVRPLVP
     EVTHGRIASF FKSGYDVGEL CSKGYMSVPQ VLCAVTRTVS TDAEGSLRIY LADLGDKELS
     PIDGQCVSLH NHDLPALVSF QPTYDCPMET VGNRKRCFAV VIERHGYIGY TGTTASVCSN
     WQARFSSKNN NYTHIAAGKT LVLPFNRLAE QTKPSAVARL LKSQLNNIES SQYLLTNAKI
     NQNARSESEE LNVESPPAAI GSSSASRSEA FRPQVVNGL