MVP_FMVD
ID MVP_FMVD Reviewed; 323 AA.
AC P09520;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 02-DEC-2020, entry version 62.
DE RecName: Full=Movement protein;
DE Short=Mov;
DE AltName: Full=Cell-to-cell transport protein;
GN ORFNames=ORF I;
OS Figwort mosaic virus (strain DxS) (FMV).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Caulimoviridae; Caulimovirus.
OX NCBI_TaxID=10650;
OH NCBI_TaxID=46031; Scrophularia californica (California bee plant).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3671088; DOI=10.1093/nar/15.20.8451;
RA Richins R.D., Scholthof H.B., Shepherd R.J.;
RT "Sequence of figwort mosaic virus DNA (caulimovirus group).";
RL Nucleic Acids Res. 15:8451-8466(1987).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Acts by forming tubules structures that increase the size
CC exclusion limit (SEL) of plasmodesmata, thereby allowing viral
CC ribonucleocapsids to spread directly to neighboring cells (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homotrimer, through the coiled-coil domain. Interacts with
CC VAP. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC {ECO:0000250}. Note=Assembles in tubules that are embedded within
CC modified plasmodesmata.
CC -!- SIMILARITY: Belongs to the caulimoviridae movement protein family.
CC {ECO:0000305}.
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DR EMBL; X06166; CAA29523.1; -; Genomic_DNA.
DR PIR; S01279; S01279.
DR RefSeq; NP_619544.1; NC_003554.1.
DR GeneID; 940161; -.
DR KEGG; vg:940161; -.
DR Proteomes; UP000008622; Genome.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR028919; Viral_movement.
DR Pfam; PF01107; MP; 1.
PE 3: Inferred from homology;
KW Coiled coil; Host cell junction; Reference proteome; Transport;
KW Viral movement protein.
FT CHAIN 1..323
FT /note="Movement protein"
FT /id="PRO_0000222065"
FT COILED 292..322
FT /evidence="ECO:0000250"
SQ SEQUENCE 323 AA; 37005 MW; AFC2523EAD1F1DF4 CRC64;
MCSTRKTSVM DEKVIENEEI HFQENSNGFS ADLTIHQDKL KQISKTGLNL EKEHIFNMPS
SLTKAFKTAF KRKNEIFYCV STKEMSVDIK DVSGQVYLPL ITKQEIQQKL MKIDPSVRSK
ISMIHLGAVK ILLTAQFRQG IDTSVKMALI DDRIVNRKDS LLGAARGNLA YGKFMFTVYP
KFALSLQSKN LDKTLSFIHQ FERKDLMKTG DKVFTVTYLI GYALTNSHHS IEYRKNSNIE
IEEVFKDIGQ IEESPFCDIS PIDENWTMDI ARNKKSIATG SSSRRNFRID ESLLENKDEN
LLRSMSTKID TLGKKLSLIY DNE