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MVP_GRVMC
ID   MVP_GRVMC               Reviewed;         260 AA.
AC   Q67685;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Movement protein;
GN   ORFNames=ORF4;
OS   Groundnut rosette virus (strain MC1) (GRV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC   Tolivirales; Tombusviridae; Calvusvirinae; Umbravirus.
OX   NCBI_TaxID=1005060;
OH   NCBI_TaxID=43365; Clitoria.
OH   NCBI_TaxID=35936; Lablab purpureus (Hyacinth bean) (Dolichos lablab).
OH   NCBI_TaxID=3879; Medicago sativa (Alfalfa).
OH   NCBI_TaxID=3885; Phaseolus vulgaris (Kidney bean) (French bean).
OH   NCBI_TaxID=3917; Vigna unguiculata (Cowpea).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8811035; DOI=10.1099/0022-1317-77-9-2335;
RA   Taliansky M.E., Robinson D.J., Murant A.F.;
RT   "Complete nucleotide sequence and organization of the RNA genome of
RT   groundnut rosette umbravirus.";
RL   J. Gen. Virol. 77:2335-2345(1996).
RN   [2]
RP   FUNCTION, AND RNA-BINDING.
RX   PubMed=11562550; DOI=10.1099/0022-1317-82-10-2579;
RA   Nurkiyanova K.M., Ryabov E.V., Kalinina N.O., Fan Y., Andreev I.,
RA   Fitzgerald A.G., Palukaitis P., Taliansky M.;
RT   "Umbravirus-encoded movement protein induces tubule formation on the
RT   surface of protoplasts and binds RNA incompletely and non-cooperatively.";
RL   J. Gen. Virol. 82:2579-2588(2001).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Might act by forming tubules structures that increase the
CC       size exclusion limit (SEL) of plasmodesmata, thereby allowing viral
CC       ribonucleoproteins to spread directly to neighboring cells. Binds to
CC       ssRNA. {ECO:0000269|PubMed:11562550}.
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DR   EMBL; Z69910; CAA93801.1; -; Genomic_RNA.
DR   RefSeq; NP_619661.1; NC_003603.1.
DR   GeneID; 940199; -.
DR   KEGG; vg:940199; -.
DR   Proteomes; UP000008927; Genome.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000603; MPV.
DR   Pfam; PF00803; 3A; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; RNA-binding; Transport; Viral movement protein.
FT   CHAIN           1..260
FT                   /note="Movement protein"
FT                   /id="PRO_0000409933"
FT   REGION          230..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   260 AA;  28455 MW;  F81746F2ED99B4D9 CRC64;
     MSSQVAKAAT QGELLEALYG EVTVQELQET NLGVLTPHRG DQRVVFTPLL PPRTQTRISG
     VLRRLRPTRN TGGLLYLEKV VVVFTPHVPD DAPGEVEVWI HDSLLPNLNS VGPRLRFPLN
     GGPRLMAFYP PYSIPLMDKS KEMPRCFAIV SELLSASYVG GGSPFSLHIM WQPQVESLAH
     NYLMRPPRMQ KICRGMVKDA LGSLSSRKSY IAGAVSHRFA LTAANPLPIS GDTAEEAGEA
     SSGEPHWVPE ATAPRVRKAT
 
 
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