MVP_GRVMC
ID MVP_GRVMC Reviewed; 260 AA.
AC Q67685;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 54.
DE RecName: Full=Movement protein;
GN ORFNames=ORF4;
OS Groundnut rosette virus (strain MC1) (GRV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC Tolivirales; Tombusviridae; Calvusvirinae; Umbravirus.
OX NCBI_TaxID=1005060;
OH NCBI_TaxID=43365; Clitoria.
OH NCBI_TaxID=35936; Lablab purpureus (Hyacinth bean) (Dolichos lablab).
OH NCBI_TaxID=3879; Medicago sativa (Alfalfa).
OH NCBI_TaxID=3885; Phaseolus vulgaris (Kidney bean) (French bean).
OH NCBI_TaxID=3917; Vigna unguiculata (Cowpea).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=8811035; DOI=10.1099/0022-1317-77-9-2335;
RA Taliansky M.E., Robinson D.J., Murant A.F.;
RT "Complete nucleotide sequence and organization of the RNA genome of
RT groundnut rosette umbravirus.";
RL J. Gen. Virol. 77:2335-2345(1996).
RN [2]
RP FUNCTION, AND RNA-BINDING.
RX PubMed=11562550; DOI=10.1099/0022-1317-82-10-2579;
RA Nurkiyanova K.M., Ryabov E.V., Kalinina N.O., Fan Y., Andreev I.,
RA Fitzgerald A.G., Palukaitis P., Taliansky M.;
RT "Umbravirus-encoded movement protein induces tubule formation on the
RT surface of protoplasts and binds RNA incompletely and non-cooperatively.";
RL J. Gen. Virol. 82:2579-2588(2001).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Might act by forming tubules structures that increase the
CC size exclusion limit (SEL) of plasmodesmata, thereby allowing viral
CC ribonucleoproteins to spread directly to neighboring cells. Binds to
CC ssRNA. {ECO:0000269|PubMed:11562550}.
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DR EMBL; Z69910; CAA93801.1; -; Genomic_RNA.
DR RefSeq; NP_619661.1; NC_003603.1.
DR GeneID; 940199; -.
DR KEGG; vg:940199; -.
DR Proteomes; UP000008927; Genome.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR000603; MPV.
DR Pfam; PF00803; 3A; 1.
PE 1: Evidence at protein level;
KW Reference proteome; RNA-binding; Transport; Viral movement protein.
FT CHAIN 1..260
FT /note="Movement protein"
FT /id="PRO_0000409933"
FT REGION 230..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 260 AA; 28455 MW; F81746F2ED99B4D9 CRC64;
MSSQVAKAAT QGELLEALYG EVTVQELQET NLGVLTPHRG DQRVVFTPLL PPRTQTRISG
VLRRLRPTRN TGGLLYLEKV VVVFTPHVPD DAPGEVEVWI HDSLLPNLNS VGPRLRFPLN
GGPRLMAFYP PYSIPLMDKS KEMPRCFAIV SELLSASYVG GGSPFSLHIM WQPQVESLAH
NYLMRPPRMQ KICRGMVKDA LGSLSSRKSY IAGAVSHRFA LTAANPLPIS GDTAEEAGEA
SSGEPHWVPE ATAPRVRKAT