ID   MVP_ICMV                Reviewed;         287 AA.
AC   Q08594;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Movement protein BC1;
DE   AltName: Full=Movement protein BL1;
GN   ORFNames=BC1, BL1;
OS   Indian cassava mosaic virus (ICMV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=31600;
OH   NCBI_TaxID=3983; Manihot esculenta (Cassava) (Jatropha manihot).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8245859; DOI=10.1099/0022-1317-74-11-2437;
RA   Hong Y.G., Robinson D.J., Harrison B.D.;
RT   "Nucleotide sequence evidence for the occurrence of three distinct
RT   whitefly-transmitted geminiviruses in cassava.";
RL   J. Gen. Virol. 74:2437-2443(1993).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Begomovirus genome is shuttled out of nucleus by Nuclear
CC       shuttle protein (NSP) and the movement protein transports the DNA-NSP
CC       complex to cell plasmodesmata and facilitates further movement across
CC       the cell wall (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Binds to dimeric supercoiled plasmid DNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host
CC       microsome membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host endoplasmic
CC       reticulum membrane {ECO:0000250}; Peripheral membrane protein
CC       {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Found on ER-derived
CC       vesicles. {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the begomovirus movement protein BC1 family.
CC       {ECO:0000305}.
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DR   EMBL; Z24759; CAA80893.1; -; Genomic_DNA.
DR   PIR; JQ2331; JQ2331.
DR   RefSeq; NP_047236.1; NC_001933.1.
DR   PRIDE; Q08594; -.
DR   GeneID; 991063; -.
DR   KEGG; vg:991063; -.
DR   Proteomes; UP000007210; Genome.
DR   GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR000211; Gemini_BL.
DR   Pfam; PF00845; Gemini_BL1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Host cell membrane; Host endoplasmic reticulum; Host membrane;
KW   Host microsome; Membrane; Phosphoprotein; Reference proteome; Transport;
KW   Viral movement protein.
FT   CHAIN           1..287
FT                   /note="Movement protein BC1"
FT                   /id="PRO_0000222255"
SQ   SEQUENCE   287 AA;  32720 MW;  9AB93914B3271BB4 CRC64;
     MENNSSNAAY LRSERVEYEL TNDSTDVKLS FPSLLDNKIS LLKGHCCKID HIVLEYRNQV
     PINATGHVII EIHDQRLHDG DSKQAEFTIP VQCNCNLHYY SSSFSTMKDI NPWRVMYRVV
     DTNVINGVHF CRIQGKLKLV NCKRSPNDIQ FRSPKIEILS KAFTERDIDF WSVGRKAQQR
     KLVQGPSLIG SRSMRYAPCS IGPNESWAVR SELGLHEPWA VKERGWASIE RPYNQLNRLN
     PDALDPGKSV SQVGSDQFTR EDLNDIISKT VNICLNTSMQ SHVSKNV