MVP_PYMVV
ID MVP_PYMVV Reviewed; 293 AA.
AC P27267;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Movement protein BC1;
DE AltName: Full=Movement protein BL1;
GN ORFNames=BC1, BL1;
OS Potato yellow mosaic virus (isolate Venezuela) (PYMV).
OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC Geplafuvirales; Geminiviridae; Begomovirus.
OX NCBI_TaxID=223310;
OH NCBI_TaxID=4113; Solanum tuberosum (Potato).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1856690; DOI=10.1099/0022-1317-72-7-1515;
RA Coutts R.H.A., Coffin R.S., Roberts E.J.F., Hamilton W.D.O.;
RT "The nucleotide sequence of the infectious cloned DNA components of potato
RT yellow mosaic virus.";
RL J. Gen. Virol. 72:1515-1520(1991).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Begomovirus genome is shuttled out of nucleus by Nuclear
CC shuttle protein (NSP) and the movement protein transports the DNA-NSP
CC complex to cell plasmodesmata and facilitates further movement across
CC the cell wall (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Binds to dimeric supercoiled plasmid DNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Host cell membrane {ECO:0000250}; Peripheral
CC membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host
CC microsome membrane {ECO:0000250}; Peripheral membrane protein
CC {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Host endoplasmic
CC reticulum membrane {ECO:0000250}; Peripheral membrane protein
CC {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Found on ER-derived
CC vesicles. {ECO:0000250}.
CC -!- PTM: Phosphorylated. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the begomovirus movement protein BC1 family.
CC {ECO:0000305}.
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DR EMBL; D00941; BAA00784.1; -; Genomic_DNA.
DR PIR; JU0362; QQCVPY.
DR RefSeq; NP_047242.1; NC_001935.1.
DR GeneID; 956392; -.
DR KEGG; vg:956392; -.
DR Proteomes; UP000006828; Genome.
DR GO; GO:0044167; C:host cell endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR000211; Gemini_BL.
DR Pfam; PF00845; Gemini_BL1; 1.
PE 3: Inferred from homology;
KW DNA-binding; Host cell membrane; Host endoplasmic reticulum; Host membrane;
KW Host microsome; Membrane; Phosphoprotein; Transport;
KW Viral movement protein.
FT CHAIN 1..293
FT /note="Movement protein BC1"
FT /id="PRO_0000222256"
SQ SEQUENCE 293 AA; 33280 MW; 9C82477FD8AF5827 CRC64;
MNSQLVNPPH AFNYIESQRD EYQLSHDLTE IILQFPSTAA QLTARLSRSC MKIDHCVIEY
RQQVPINATG SVIVEIHDKR MTDNESLQAS WTFPLRCNID LHYFSASFFS LKDPIPWKLY
YRVSDTNVHQ RTHFAKFKGK LKLSTAKHSV DIPFRAPTVK ILSKQFTDKD VDFSHVDYGR
WERKPIRCAS MSRVGLRGPI EIRPGESWAS RSTIGVGQSE GESEIENELH TYRDLQRLGA
SVLDPGESAS IVGANMAQSN ITMSVAQLNE LVRTTVQECI KSNCNSSQPK NFK