MVP_TMGMV
ID MVP_TMGMV Reviewed; 266 AA.
AC P18338; Q88597;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2000, sequence version 2.
DT 02-JUN-2021, entry version 77.
DE RecName: Full=Movement protein;
DE AltName: Full=28.5 kDa protein;
DE AltName: Full=Cell-to-cell transport protein;
GN Name=MP;
OS Tobacco mild green mosaic virus (TMGMV) (TMV strain U2).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Virgaviridae; Tobamovirus.
OX NCBI_TaxID=12241;
OH NCBI_TaxID=4072; Capsicum annuum (Capsicum pepper).
OH NCBI_TaxID=43071; Eryngium planum.
OH NCBI_TaxID=4090; Nicotiana glauca (Glaucous tobacco) (Tree tobacco).
OH NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2371769; DOI=10.1016/0042-6822(90)90520-2;
RA Solis I., Garcia-Arenal F.;
RT "The complete nucleotide sequence of the genomic RNA of the tobamovirus
RT tobacco mild green mosaic virus.";
RL Virology 177:553-558(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=1984654; DOI=10.1016/0042-6822(91)90036-b;
RA Nejidat A., Cellier F., Holt C.A., Gafny R., Eggenberger A.L., Beachy R.N.;
RT "Transfer of the movement protein gene between two tobamoviruses: influence
RT on local lesion development.";
RL Virology 180:318-326(1991).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Forms a ribonucleoprotein complex with viral RNA. Binds
CC microtubules and modulates microtubule stability. Can bind double-
CC stranded DNA. {ECO:0000250|UniProtKB:P03583,
CC ECO:0000250|UniProtKB:P69513}.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm, host cytoskeleton
CC {ECO:0000250|UniProtKB:P69513}. Host cell junction, host plasmodesma
CC {ECO:0000250|UniProtKB:P69513}.
CC -!- SIMILARITY: Belongs to the tobamovirus movement protein family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M34077; AAA47936.1; -; Genomic_RNA.
DR EMBL; M34236; AAA47938.1; -; Genomic_RNA.
DR PIR; B35520; WMTMU2.
DR RefSeq; NP_062915.1; NC_001556.1.
DR GeneID; 1494076; -.
DR KEGG; vg:1494076; -.
DR Proteomes; UP000000281; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR001022; TMV_movement.
DR InterPro; IPR028919; Viral_movement.
DR Pfam; PF01107; MP; 1.
DR PRINTS; PR00964; MOVEMENT.
PE 3: Inferred from homology;
KW Host cell junction; Host cytoplasm; Host cytoskeleton; RNA-binding;
KW Transport; Viral movement protein.
FT CHAIN 1..266
FT /note="Movement protein"
FT /id="PRO_0000144966"
FT REGION 212..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..226
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 16
FT /note="N -> D (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 64
FT /note="N -> K (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 71
FT /note="G -> D (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 101
FT /note="N -> K (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 135
FT /note="N -> H (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 171
FT /note="K -> R (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 180
FT /note="R -> S (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 184
FT /note="D -> G (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 209..227
FT /note="RFRKTKKGKKRKKEKKKRV -> KVPENKKEM (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 231
FT /note="S -> N (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
FT CONFLICT 245..247
FT /note="LKV -> FKI (in Ref. 1; AAA47936)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 266 AA; 29711 MW; CBF383DBDE188C2A CRC64;
MAVSLRDTVK ISEFINLSKQ DEILPAFMTK VKSVRISTVD KIMAVKNDSL SDVDLLKGVK
LVKNGYVCLA GLVVSGEWNL PDNCRGGVSV CIVDKRMKRS NEATLGAYHA PACKKNFSFK
LIPNYSITSE DAEKNPWQVL VNIKGVAMEE GYCPLSLEFV SICVVHKNNV KKGLRERILR
VTDDSPIELT EKVVEEFVDE VPMAVKLERF RKTKKGKKRK KEKKKRVVGN SVNNKKINNS
GKKGLKVEEI EDNVSDDESI ASSSTF
