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MVP_TMOB
ID   MVP_TMOB                Reviewed;         274 AA.
AC   Q83485;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Movement protein;
DE   AltName: Full=30 kDa protein;
DE   AltName: Full=Cell-to-cell transport protein;
GN   Name=MP;
OS   Tobamovirus Ob.
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Martellivirales; Virgaviridae; Tobamovirus.
OX   NCBI_TaxID=31749;
OH   NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=8376970; DOI=10.1099/0022-1317-74-9-1939;
RA   Ikeda R., Watanabe E., Watanabe Y., Okada Y.;
RT   "Nucleotide sequence of tobamovirus Ob which can spread systemically in N
RT   gene tobacco.";
RL   J. Gen. Virol. 74:1939-1944(1993).
CC   -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC       through plasmosdesmata, without any budding. The movement protein
CC       allows efficient cell to cell propagation, by bypassing the host cell
CC       wall barrier. Forms a ribonucleoprotein complex with viral RNA. Binds
CC       microtubules and modulates microtubule stability. Can bind double-
CC       stranded DNA. {ECO:0000250|UniProtKB:P03583,
CC       ECO:0000250|UniProtKB:P69513}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm, host cytoskeleton
CC       {ECO:0000250|UniProtKB:P69513}. Host cell junction, host plasmodesma
CC       {ECO:0000250|UniProtKB:P69513}.
CC   -!- SIMILARITY: Belongs to the tobamovirus movement protein family.
CC       {ECO:0000305}.
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DR   EMBL; D13438; BAA02702.1; -; Genomic_RNA.
DR   RefSeq; NP_620843.1; NC_003852.1.
DR   SMR; Q83485; -.
DR   GeneID; 944439; -.
DR   KEGG; vg:944439; -.
DR   Proteomes; UP000008248; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR   GO; GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR   InterPro; IPR001022; TMV_movement.
DR   InterPro; IPR028919; Viral_movement.
DR   Pfam; PF01107; MP; 1.
DR   PRINTS; PR00964; MOVEMENT.
PE   3: Inferred from homology;
KW   Host cell junction; Host cytoplasm; Host cytoskeleton; Reference proteome;
KW   RNA-binding; Transport; Viral movement protein.
FT   CHAIN           1..274
FT                   /note="Movement protein"
FT                   /id="PRO_0000144967"
FT   REGION          209..274
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..274
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   274 AA;  30617 MW;  995C44F3CA73F9AF CRC64;
     MSKAIVKIDE FIKLSKSEEV LPSAFTRMKS VRVSTVDKIM AKENDNISEV DLLKGVKLVK
     NGYVCLVGLV VSGEWNLPDN CRGGVSICLI DKRMQRHNEA TLGSYTTKAS KKNFSFKLIP
     NYSITSQDAE RRPWEVMVNI RGVAMSEGWC PLSLEFVSVC IVHKNNVRKG LREKVTAVSE
     DDAIELTEEV VDEFIEAVPM ARRLQNLRKP KYNKEKENKN LNNKNSIGVS KPVGLERNKV
     RSVVRKGVRS DSSLGVTDMS QDGSSSEISS DSFI
 
 
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