MVP_TMOB
ID MVP_TMOB Reviewed; 274 AA.
AC Q83485;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Movement protein;
DE AltName: Full=30 kDa protein;
DE AltName: Full=Cell-to-cell transport protein;
GN Name=MP;
OS Tobamovirus Ob.
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Virgaviridae; Tobamovirus.
OX NCBI_TaxID=31749;
OH NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=8376970; DOI=10.1099/0022-1317-74-9-1939;
RA Ikeda R., Watanabe E., Watanabe Y., Okada Y.;
RT "Nucleotide sequence of tobamovirus Ob which can spread systemically in N
RT gene tobacco.";
RL J. Gen. Virol. 74:1939-1944(1993).
CC -!- FUNCTION: Transports viral genome to neighboring plant cells directly
CC through plasmosdesmata, without any budding. The movement protein
CC allows efficient cell to cell propagation, by bypassing the host cell
CC wall barrier. Forms a ribonucleoprotein complex with viral RNA. Binds
CC microtubules and modulates microtubule stability. Can bind double-
CC stranded DNA. {ECO:0000250|UniProtKB:P03583,
CC ECO:0000250|UniProtKB:P69513}.
CC -!- SUBCELLULAR LOCATION: Host cytoplasm, host cytoskeleton
CC {ECO:0000250|UniProtKB:P69513}. Host cell junction, host plasmodesma
CC {ECO:0000250|UniProtKB:P69513}.
CC -!- SIMILARITY: Belongs to the tobamovirus movement protein family.
CC {ECO:0000305}.
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DR EMBL; D13438; BAA02702.1; -; Genomic_RNA.
DR RefSeq; NP_620843.1; NC_003852.1.
DR SMR; Q83485; -.
DR GeneID; 944439; -.
DR KEGG; vg:944439; -.
DR Proteomes; UP000008248; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0044163; C:host cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR001022; TMV_movement.
DR InterPro; IPR028919; Viral_movement.
DR Pfam; PF01107; MP; 1.
DR PRINTS; PR00964; MOVEMENT.
PE 3: Inferred from homology;
KW Host cell junction; Host cytoplasm; Host cytoskeleton; Reference proteome;
KW RNA-binding; Transport; Viral movement protein.
FT CHAIN 1..274
FT /note="Movement protein"
FT /id="PRO_0000144967"
FT REGION 209..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 30617 MW; 995C44F3CA73F9AF CRC64;
MSKAIVKIDE FIKLSKSEEV LPSAFTRMKS VRVSTVDKIM AKENDNISEV DLLKGVKLVK
NGYVCLVGLV VSGEWNLPDN CRGGVSICLI DKRMQRHNEA TLGSYTTKAS KKNFSFKLIP
NYSITSQDAE RRPWEVMVNI RGVAMSEGWC PLSLEFVSVC IVHKNNVRKG LREKVTAVSE
DDAIELTEEV VDEFIEAVPM ARRLQNLRKP KYNKEKENKN LNNKNSIGVS KPVGLERNKV
RSVVRKGVRS DSSLGVTDMS QDGSSSEISS DSFI