MVP_TYYVF
ID MVP_TYYVF Reviewed; 175 AA.
AC P09511;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=Movement protein;
DE Short=MP;
DE AltName: Full=20 kDa protein;
GN ORFNames=ORF4;
OS Turnip yellows virus (isolate FL-1) (TuYV) (BWYV-FL1).
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Sobelivirales; Solemoviridae; Polerovirus.
OX NCBI_TaxID=12043;
OH NCBI_TaxID=161934; Beta vulgaris (Sugar beet).
OH NCBI_TaxID=3709; Brassica napus subsp. rapifera.
OH NCBI_TaxID=138011; Brassica napus var. napus.
OH NCBI_TaxID=3710; Brassica nigra (Black mustard) (Sinapis nigra).
OH NCBI_TaxID=3715; Brassica oleracea var. botrytis (Cauliflower).
OH NCBI_TaxID=3716; Brassica oleracea var. capitata (Cabbage).
OH NCBI_TaxID=51350; Brassica rapa subsp. rapa (Turnip).
OH NCBI_TaxID=4072; Capsicum annuum (Capsicum pepper).
OH NCBI_TaxID=3827; Cicer arietinum (Chickpea) (Garbanzo).
OH NCBI_TaxID=3654; Citrullus lanatus (Watermelon) (Citrullus vulgaris).
OH NCBI_TaxID=3721; Crambe hispanica subsp. abyssinica (Abyssinian kale) (Crambe abyssinica).
OH NCBI_TaxID=3659; Cucumis sativus (Cucumber).
OH NCBI_TaxID=3663; Cucurbita pepo (Vegetable marrow) (Summer squash).
OH NCBI_TaxID=3847; Glycine max (Soybean) (Glycine hispida).
OH NCBI_TaxID=4232; Helianthus annuus (Common sunflower).
OH NCBI_TaxID=4236; Lactuca sativa (Garden lettuce).
OH NCBI_TaxID=103529; Phlox drummondii (Annual phlox).
OH NCBI_TaxID=3888; Pisum sativum (Garden pea).
OH NCBI_TaxID=3726; Raphanus sativus (Radish) (Raphanus raphanistrum var. sativus).
OH NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH NCBI_TaxID=3562; Spinacia oleracea (Spinach).
OH NCBI_TaxID=3900; Trifolium subterraneum (Subterranean clover).
OH NCBI_TaxID=3906; Vicia faba (Broad bean) (Faba vulgaris).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=3194229; DOI=10.1093/nar/16.21.9917;
RA Veidt I., Lot H., Leiser M., Scheidecker D., Guilley H., Richards K.E.,
RA Jonard G.;
RT "Nucleotide sequence of beet western yellows virus RNA.";
RL Nucleic Acids Res. 16:9917-9932(1988).
RN [2]
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=25946037; DOI=10.1371/journal.ppat.1004868;
RA Smirnova E., Firth A.E., Miller W.A., Scheidecker D., Brault V.,
RA Reinbold C., Rakotondrafara A.M., Chung B.Y., Ziegler-Graff V.;
RT "Discovery of a small non-AUG-initiated ORF in Poleroviruses and
RT Luteoviruses that is required for long-distance movement.";
RL PLoS Pathog. 11:E1004868-E1004868(2015).
CC -!- FUNCTION: Together with movement protein P3a, facilitates long-distance
CC movement of virions in host (PubMed:25946037). Transports viral genome
CC to neighboring plant cells directly through plasmosdesmata, without any
CC budding (Probable). The movement protein allows efficient cell to cell
CC propagation, by bypassing the host cell wall barrier (Probable). Binds
CC ssRNA (By similarity). {ECO:0000250|UniProtKB:P10471,
CC ECO:0000269|PubMed:25946037, ECO:0000305}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250|UniProtKB:P10471}.
CC -!- SUBCELLULAR LOCATION: Host cell junction, host plasmodesma
CC {ECO:0000269|PubMed:25946037}. Host Golgi apparatus
CC {ECO:0000269|PubMed:25946037}.
CC -!- DOMAIN: The N-terminus is involved in homodimerization (By similarity).
CC The C-terminus binds ssRNA (By similarity). The C-terminus is
CC phosphorylated (By similarity). {ECO:0000250|UniProtKB:P10471}.
CC -!- PTM: Phosphorylated. {ECO:0000250|UniProtKB:P10471}.
CC -!- MISCELLANEOUS: Poleroviruses are transmitted by aphids directly into
CC phloem tissue. The virus replicates most efficiently in phloem
CC companion cells and then moves through plasmodesmata between companion
CC cells or into sieve elements for long distance transport.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the polerovirus movement protein family.
CC {ECO:0000305}.
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DR EMBL; X13063; CAA31466.1; -; Genomic_RNA.
DR PIR; S01942; GNVQFL.
DR RefSeq; NP_620489.1; NC_003743.1.
DR GeneID; 940482; -.
DR KEGG; vg:940482; -.
DR Proteomes; UP000007545; Genome.
DR GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0044219; C:host cell plasmodesma; IEA:UniProtKB-SubCell.
DR GO; GO:0046740; P:transport of virus in host, cell to cell; IEA:UniProtKB-KW.
DR InterPro; IPR001964; Luteo_VPG.
DR Pfam; PF01659; Luteo_Vpg; 1.
DR PRINTS; PR00912; LVIRUSORF5.
PE 3: Inferred from homology;
KW Host cell junction; Host Golgi apparatus; Phosphoprotein;
KW Reference proteome; Transport; Viral movement protein.
FT CHAIN 1..175
FT /note="Movement protein"
FT /id="PRO_0000222416"
FT REGION 30..47
FT /note="Homodimerization"
FT /evidence="ECO:0000250|UniProtKB:P10471"
FT REGION 50..156
FT /note="RNA-binding"
FT /evidence="ECO:0000250|UniProtKB:P10471"
FT REGION 116..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 64
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P10471"
FT MOD_RES 133
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:P10471"
SQ SEQUENCE 175 AA; 19567 MW; 8843F35A54C16FCD CRC64;
MEEDDHAGKH DALSALSQWL WSKPLGQHNA DLDDDEEVTT GQEELFLPEE QVRARHLFSQ
KTISREVPAE QSRSGRVYQT ARHSLMECSR PTMSIKSQWS FWSSSPKPLP KIPVPSLTSW
THTVNSTPFP QLSTSSGSQS PGKGRLQRLT STERNGTTLP RTNSGSSTKA MVLHR
