ID   MXIE_SHISO              Reviewed;         210 AA.
AC   P0A2S8; Q04642; Q55292;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Transcriptional regulator MxiE;
GN   Name=mxiE;
OS   Shigella sonnei.
OG   Plasmid pINV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HW383;
RA   Arakawa E., Kato J., Ito K., Watanabe H.;
RT   "Comparison and high conservation of nucleotide sequences of spa-mxi
RT   regions between S.sonnei and S.flexneri -- identification of a new gene
RT   coding plausible membrane protein.";
RL   Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Necessary for the secretion of ipa invasins. Probable
CC       transcriptional regulatory protein (By similarity). {ECO:0000250}.
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DR   EMBL; D50601; BAA09153.1; -; Genomic_DNA.
DR   RefSeq; WP_000398259.1; NZ_WHSK01000249.1.
DR   AlphaFoldDB; P0A2S8; -.
DR   SMR; P0A2S8; -.
DR   STRING; 216599.GCA_000283715_05235; -.
DR   OMA; LESYWLA; -.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR018062; HTH_AraC-typ_CS.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Plasmid; Transcription; Transcription regulation; Transport;
KW   Virulence.
FT   CHAIN           1..210
FT                   /note="Transcriptional regulator MxiE"
FT                   /id="PRO_0000194542"
FT   DOMAIN          99..199
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        118..139
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        166..189
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   210 AA;  24552 MW;  84AA9268852A47DF CRC64;
     MEGFFFVRNQ NIKFSDNVNY HYRFNINSCA KFLAFWDYFS GALVEHSHAE KCIHFYHEND
     LRDSCNTESM LDKLMLRFIF SSDQNVSNAL AMIRMTESYH LVLYLLRTIE KEKEVRIKSL
     TEHYGVSEAY FRSLCRKALG AKVKEQLNTW RLVNGLLDVF LHNQTITSAA MNNGYASTSH
     FSNEIKTRLG FSARELSNIT FLVKKINEKI