ID   MXIG_SHISO              Reviewed;         371 AA.
AC   P0A222; Q57332;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Protein MxiG;
GN   Name=mxiG;
OS   Shigella sonnei.
OG   Plasmid pINV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=624;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=HW383;
RA   Arakawa E., Kato J., Ito K., Watanabe H.;
RT   "Comparison and high conservation of nucleotide sequences of spa-mxi
RT   regions between S.sonnei and S.flexneri -- identification of a new gene
RT   coding plausible membrane protein.";
RL   Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the secretion of the Ipa antigens. Involved in
CC       the intracellular dissemination of Shigella. Part of the Mxi-Spa
CC       secretion apparatus (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Single-pass
CC       type II membrane protein {ECO:0000250}. Cell outer membrane
CC       {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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DR   EMBL; D50601; BAA09145.1; -; Genomic_DNA.
DR   RefSeq; WP_001287353.1; NZ_WHSK01000208.1.
DR   AlphaFoldDB; P0A222; -.
DR   BMRB; P0A222; -.
DR   SMR; P0A222; -.
DR   STRING; 216599.GCA_000283715_05227; -.
DR   OMA; HIQFSIS; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019029; T3SS_PrgH/EprH-like.
DR   Pfam; PF09480; PrgH; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Cell outer membrane; Membrane; Plasmid;
KW   Transmembrane; Transmembrane helix; Virulence.
FT   CHAIN           1..371
FT                   /note="Protein MxiG"
FT                   /id="PRO_0000096658"
FT   TRANSMEM        127..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   371 AA;  43002 MW;  9B137FE9A955C3E6 CRC64;
     MSEAKNSNLA PFRLLVKLTN GVGDEFPLYY GNNLIVLGRT IETLEFGNDN FPENIIPVTD
     SKSDGIIYLT ISKDNICQFS DEKGEQIDIN SQFNSFEYDG ISFHLKNMRE DKSRGHILNG
     MYKNHSVFFF FAVIVVLIII FSLSLKKDEV KEIAEIIDDK RYGIVNTGQC NYILAETQND
     AVWASVALNK TGFTKCRYIL VSNKEINRIQ QYINQRFPFI NLYVLNLVSD KAELLVFLSK
     ERNSSKDTEL DKLKNALIVE FPYIKNIKFN YLSDHNARGD AKGIFTKVNV QYKEICENNK
     VTYSVREELT DEKLELINRL ISEHKNIYGD QYIEFSVLLI DDDFKGKSYL NSKDSYVMLN
     DKHWFFLDKN K