MXIJ_SHIFL
ID MXIJ_SHIFL Reviewed; 241 AA.
AC Q06081;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 25-MAY-2022, entry version 133.
DE RecName: Full=Lipoprotein MxiJ;
DE Flags: Precursor;
GN Name=mxiJ; OrderedLocusNames=CP0139;
OS Shigella flexneri.
OG Plasmid pWR100, and Plasmid pCP301.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=M90T / Serotype 5a; PLASMID=pWR100;
RX PubMed=1332940; DOI=10.1128/jb.174.23.7661-7669.1992;
RA Allaoui A., Sansonetti P.J., Parsot C.;
RT "MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is
RT homologous to YscJ, a secretion factor of the Yersinia Yop proteins.";
RL J. Bacteriol. 174:7661-7669(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=M90T / Serotype 5a; PLASMID=pWR100;
RX PubMed=11115111; DOI=10.1046/j.1365-2958.2000.02179.x;
RA Buchrieser C., Glaser P., Rusniok C., Nedjari H., d'Hauteville H.,
RA Kunst F., Sansonetti P.J., Parsot C.;
RT "The virulence plasmid pWR100 and the repertoire of proteins secreted by
RT the type III secretion apparatus of Shigella flexneri.";
RL Mol. Microbiol. 38:760-771(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=M90T / Serotype 5a; PLASMID=pWR100;
RX PubMed=11292750; DOI=10.1128/iai.69.5.3271-3285.2001;
RA Venkatesan M.M., Goldberg M.B., Rose D.J., Grotbeck E.J., Burland V.,
RA Blattner F.R.;
RT "Complete DNA sequence and analysis of the large virulence plasmid of
RT Shigella flexneri.";
RL Infect. Immun. 69:3271-3285(2001).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a; PLASMID=pCP301;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
CC -!- FUNCTION: Involved in the secretion of the Ipa antigens.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the YscJ lipoprotein family. {ECO:0000305}.
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DR EMBL; M98390; AAA26532.1; -; Genomic_DNA.
DR EMBL; AL391753; CAC05814.1; -; Genomic_DNA.
DR EMBL; AF348706; AAK18458.1; -; Genomic_DNA.
DR EMBL; AF386526; AAL72328.1; -; Genomic_DNA.
DR PIR; C45271; C45271.
DR RefSeq; NP_085302.1; NC_002698.1.
DR RefSeq; NP_858272.1; NC_004851.1.
DR RefSeq; WP_000621942.1; NZ_WPGS01000043.1.
DR RefSeq; YP_009062496.1; NC_024996.1.
DR PDB; 6RWX; EM; 3.55 A; a/b/c/d/e/f/g/h/i/j/k/l/m/n/o/p/q/r/s/t/u/v/w/x=1-241.
DR PDBsum; 6RWX; -.
DR AlphaFoldDB; Q06081; -.
DR SMR; Q06081; -.
DR STRING; 198214.CP0139; -.
DR EnsemblBacteria; AAL72328; AAL72328; SF_p0139.
DR GeneID; 1238031; -.
DR KEGG; sfl:CP0139; -.
DR PATRIC; fig|198214.7.peg.5390; -.
DR HOGENOM; CLU_073268_2_0_6; -.
DR OMA; IKYRESA; -.
DR Proteomes; UP000001006; Plasmid pCP301.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR006182; FliF_N_dom.
DR InterPro; IPR003282; T3SS_HrcJ/YscJ.
DR InterPro; IPR043427; YscJ/FliF.
DR PANTHER; PTHR30046; PTHR30046; 1.
DR Pfam; PF01514; YscJ_FliF; 1.
DR PRINTS; PR01338; TYPE3OMKPROT.
DR TIGRFAMs; TIGR02544; III_secr_YscJ; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell outer membrane; Lipoprotein; Membrane; Palmitate;
KW Plasmid; Protein transport; Reference proteome; Signal; Transport;
KW Virulence.
FT SIGNAL 1..17
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 18..241
FT /note="Lipoprotein MxiJ"
FT /id="PRO_0000018223"
FT LIPID 18
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 18
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 241 AA; 27509 MW; 3D20D62033A30898 CRC64;
MIRYKGFILF LLLMLIGCEQ REELISNLSQ RQANEIISVL ERHNITARKV DGGKQGISVQ
VEKGTFASAV DLMRMYDLPN PERVDISQMF PTDSLVSSPR AEKARLYSAI EQRLEQSLVS
IGGVISAKIH VSYDLEEKNI SSKPMHISVI AIYDSPKESE LLVSNIKRFL KNTFSDVKYE
NISVILTPKE EYVYTNVQPV KEVKSEFLTN EVIYLFLGMA VLVVILLVWA FKTGWFKRNK
I