MY105_ARATH
ID MY105_ARATH Reviewed; 330 AA.
AC Q9SEZ4;
DT 12-APR-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 160.
DE RecName: Full=Transcription factor MYB105 {ECO:0000305};
DE AltName: Full=MYB-domain transcription factor LOF2 {ECO:0000303|PubMed:19542355};
DE AltName: Full=Myb-related protein 105 {ECO:0000305};
DE Short=AtMYB105 {ECO:0000303|PubMed:11597504};
DE AltName: Full=Protein LATERAL ORGAN FUSION 2 {ECO:0000303|PubMed:19542355};
GN Name=MYB105 {ECO:0000303|PubMed:11597504};
GN Synonyms=LOF2 {ECO:0000303|PubMed:19542355};
GN OrderedLocusNames=At1g69560 {ECO:0000312|Araport:AT1G69560};
GN ORFNames=F10D13.19 {ECO:0000312|EMBL:AAG60101.1},
GN F24J1.31 {ECO:0000312|EMBL:AAF24603.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP FUNCTION, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=19542355; DOI=10.1242/dev.031971;
RA Lee D.K., Geisler M., Springer P.S.;
RT "LATERAL ORGAN FUSION1 and LATERAL ORGAN FUSION2 function in lateral organ
RT separation and axillary meristem formation in Arabidopsis.";
RL Development 136:2423-2432(2009).
CC -!- FUNCTION: Probable transcription factor that involved in boundary
CC specification, meristem initiation and maintenance, and organ
CC patterning. Functions in both lateral organ separation and axillary
CC meristem formation. {ECO:0000269|PubMed:19542355}.
CC -!- INTERACTION:
CC Q9SEZ4; Q17TI5: BRX; NbExp=3; IntAct=EBI-15202260, EBI-4426649;
CC Q9SEZ4; Q9FKB0: LSM5; NbExp=3; IntAct=EBI-15202260, EBI-16419382;
CC Q9SEZ4; Q8LPR5: TCP4; NbExp=3; IntAct=EBI-15202260, EBI-15192325;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- TISSUE SPECIFICITY: Expressed in organ boundaries.
CC {ECO:0000269|PubMed:19542355}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but the double mutants lof1 and lof2 exhibit enhanced
CC phenotypes relative to lof1. {ECO:0000269|PubMed:19542355}.
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DR EMBL; AF249308; AAF65558.1; -; mRNA.
DR EMBL; AC021046; AAF24603.1; -; Genomic_DNA.
DR EMBL; AC073178; AAG60101.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34949.1; -; Genomic_DNA.
DR PIR; C96717; C96717.
DR RefSeq; NP_177115.1; NM_105625.3.
DR AlphaFoldDB; Q9SEZ4; -.
DR SMR; Q9SEZ4; -.
DR IntAct; Q9SEZ4; 21.
DR STRING; 3702.AT1G69560.1; -.
DR PaxDb; Q9SEZ4; -.
DR EnsemblPlants; AT1G69560.1; AT1G69560.1; AT1G69560.
DR GeneID; 843292; -.
DR Gramene; AT1G69560.1; AT1G69560.1; AT1G69560.
DR KEGG; ath:AT1G69560; -.
DR Araport; AT1G69560; -.
DR TAIR; locus:2007136; AT1G69560.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_18_0_1; -.
DR InParanoid; Q9SEZ4; -.
DR PhylomeDB; Q9SEZ4; -.
DR PRO; PR:Q9SEZ4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SEZ4; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0010199; P:organ boundary specification between lateral organs and the meristem; IGI:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..330
FT /note="Transcription factor MYB105"
FT /id="PRO_0000439514"
FT DOMAIN 102..153
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 154..208
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 130..152
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 181..204
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
SQ SEQUENCE 330 AA; 38440 MW; 7F700964325E8030 CRC64;
MEMVHADVAS LSITPCFPSS LSSSSHHHYN QQQHCIMSED QHHSMDQTTS SDYFSLNIDN
AQHLRSYYTS HREEDMNPNL SDYSNCNKKD TTVYRSCGHS SKASVSRGHW RPAEDTKLKE
LVAVYGPQNW NLIAEKLQGR SGKSCRLRWF NQLDPRINRR AFTEEEEERL MQAHRLYGNK
WAMIARLFPG RTDNSVKNHW HVIMARKFRE QSSSYRRRKT MVSLKPLINP NPHIFNDFDP
TRLALTHLAS SDHKQLMLPV PCFPGYDHEN ESPLMVDMFE TQMMVGDYIA WTQEATTFDF
LNQTGKSEIF ERINEEKKPP FFDFLGLGTV
