MY106_ARATH
ID MY106_ARATH Reviewed; 345 AA.
AC Q9LE63; Q6R098;
DT 10-MAY-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 151.
DE RecName: Full=Transcription factor MYB106 {ECO:0000305};
DE AltName: Full=Myb-related protein 106 {ECO:0000303|PubMed:11597504};
DE Short=AtMYB106 {ECO:0000303|PubMed:11597504};
DE AltName: Full=Transcription factor NOEK {ECO:0000303|PubMed:18805951};
GN Name=MYB106 {ECO:0000303|PubMed:11597504};
GN Synonyms=NOK {ECO:0000303|PubMed:18805951};
GN OrderedLocusNames=At3g01140 {ECO:0000312|Araport:AT3G01140};
GN ORFNames=T4P13.17 {ECO:0000312|EMBL:AAF26160.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP FUNCTION, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=18805951; DOI=10.1104/pp.108.126979;
RA Jakoby M.J., Falkenhan D., Mader M.T., Brininstool G., Wischnitzki E.,
RA Platz N., Hudson A., Huelskamp M., Larkin J., Schnittger A.;
RT "Transcriptional profiling of mature Arabidopsis trichomes reveals that
RT NOECK encodes the MIXTA-like transcriptional regulator MYB106.";
RL Plant Physiol. 148:1583-1602(2008).
RN [6]
RP FUNCTION.
RX PubMed=21070410; DOI=10.1111/j.1365-313x.2010.04329.x;
RA Gilding E.K., Marks M.D.;
RT "Analysis of purified glabra3-shapeshifter trichomes reveals a role for
RT NOECK in regulating early trichome morphogenic events.";
RL Plant J. 64:304-317(2010).
RN [7]
RP FUNCTION.
RX PubMed=23709630; DOI=10.1105/tpc.113.110783;
RA Oshima Y., Shikata M., Koyama T., Ohtsubo N., Mitsuda N., Ohme-Takagi M.;
RT "MIXTA-like transcription factors and WAX INDUCER1/SHINE1 coordinately
RT regulate cuticle development in Arabidopsis and Torenia fournieri.";
RL Plant Cell 25:1609-1624(2013).
RN [8]
RP FUNCTION.
RX PubMed=24169067; DOI=10.4161/psb.26826;
RA Oshima Y., Mitsuda N.;
RT "The MIXTA-like transcription factor MYB16 is a major regulator of cuticle
RT formation in vegetative organs.";
RL Plant Signal. Behav. 8:E26826-E26826(2013).
CC -!- FUNCTION: Functions as a repressor of epidermal cell outgrowth and
CC negatively regulate trichome branch formation (PubMed:18805951,
CC PubMed:21070410). Acts as both a positive and negative regulator of
CC cellular outgrowth. Promotes both trichome expansion and branch
CC formation (PubMed:21070410). Coordinately with WIN1/SHN1, participates
CC in the regulation of cuticle biosynthesis and wax accumulation in
CC reproductive organs and trichomes. Functions in cuticle nanoridge
CC formation in petals and stamens, and in morphogenesis of petal conical
CC cells and trichomes (PubMed:23709630). May play a role in the
CC regulation of cuticle formation in vegetative organs (PubMed:24169067).
CC {ECO:0000269|PubMed:18805951, ECO:0000269|PubMed:21070410,
CC ECO:0000269|PubMed:23709630, ECO:0000269|PubMed:24169067}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- TISSUE SPECIFICITY: Expressed in trichomes, stems, carpels, petals and
CC stamens. {ECO:0000269|PubMed:18805951}.
CC -!- DISRUPTION PHENOTYPE: Overbranched trichomes.
CC {ECO:0000269|PubMed:18805951}.
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DR EMBL; AF249309; AAF65559.1; -; mRNA.
DR EMBL; AY519581; AAS10051.1; -; mRNA.
DR EMBL; AC008261; AAF26160.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64392.1; -; Genomic_DNA.
DR RefSeq; NP_001326423.1; NM_001337322.1.
DR AlphaFoldDB; Q9LE63; -.
DR SMR; Q9LE63; -.
DR STRING; 3702.AT3G01140.1; -.
DR PRIDE; Q9LE63; -.
DR ProteomicsDB; 251207; -.
DR EnsemblPlants; AT3G01140.2; AT3G01140.2; AT3G01140.
DR GeneID; 821209; -.
DR Gramene; AT3G01140.2; AT3G01140.2; AT3G01140.
DR KEGG; ath:AT3G01140; -.
DR Araport; AT3G01140; -.
DR eggNOG; KOG0048; Eukaryota.
DR OMA; EGEREWN; -.
DR PhylomeDB; Q9LE63; -.
DR PRO; PR:Q9LE63; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LE63; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000902; P:cell morphogenesis; IMP:UniProtKB.
DR GO; GO:0035017; P:cuticle pattern formation; IMP:UniProtKB.
DR GO; GO:1901957; P:regulation of cutin biosynthetic process; IMP:UniProtKB.
DR GO; GO:0010091; P:trichome branching; IMP:UniProtKB.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..345
FT /note="Transcription factor MYB106"
FT /id="PRO_0000439928"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT CONFLICT 6
FT /note="C -> S (in Ref. 2; AAS10051)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 345 AA; 38575 MW; 1349D657B1C34ED2 CRC64;
MGRSPCCDKA GLKKGPWTPE EDQKLLAYIE EHGHGSWRSL PEKAGLQRCG KSCRLRWTNY
LRPDIKRGKF TVQEEQTIIQ LHALLGNRWS AIATHLPKRT DNEIKNYWNT HLKKRLIKMG
IDPVTHKHKN ETLSSSTGQS KNAATLSHMA QWESARLEAE ARLARESKLL HLQHYQNNNN
LNKSAAPQQH CFTQKTSTNW TKPNQGNGDQ QLESPTSTVT FSENLLMPLG IPTDSSRNRN
NNNNESSAMI ELAVSSSTSS DVSLVKEHEH DWIRQINCGS GGIGEGFTSL LIGDSVGRGL
PTGKNEATAG VGNESEYNYY EDNKNYWNSI LNLVDSSPSD SATMF
