MY123_ACTCC
ID MY123_ACTCC Reviewed; 266 AA.
AC A0A2R6PN00; A0A410R925;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2018, sequence version 1.
DT 25-MAY-2022, entry version 18.
DE RecName: Full=Transcription factor MYB123 {ECO:0000305};
DE AltName: Full=Myb-related protein 123 {ECO:0000305};
DE Short=AcMYB123 {ECO:0000303|PubMed:30912865};
GN Name=MYB123 {ECO:0000303|PubMed:30912865};
GN ORFNames=CEY00_Acc28234 {ECO:0000312|EMBL:PSR93620.1};
OS Actinidia chinensis var. chinensis (Chinese soft-hair kiwi).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Ericales; Actinidiaceae; Actinidia.
OX NCBI_TaxID=1590841;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INTERACTION WITH BHLH42, SUBCELLULAR
RP LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=30912865; DOI=10.1111/tpj.14330;
RA Wang L., Tang W., Hu Y., Zhang Y., Sun J., Guo X., Lu H., Yang Y., Fang C.,
RA Niu X., Yue J., Fei Z., Liu Y.;
RT "A MYB/bHLH complex regulates tissue-specific anthocyanin biosynthesis in
RT the inner pericarp of red-centered kiwifruit Actinidia chinensis cv.
RT Hongyang.";
RL Plant J. 99:359-378(2019).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Red5;
RX PubMed=29661190; DOI=10.1186/s12864-018-4656-3;
RA Pilkington S.M., Crowhurst R., Hilario E., Nardozza S., Fraser L., Peng Y.,
RA Gunaseelan K., Simpson R., Tahir J., Deroles S.C., Templeton K., Luo Z.,
RA Davy M., Cheng C., McNeilage M., Scaglione D., Liu Y., Zhang Q., Datson P.,
RA De Silva N., Gardiner S.E., Bassett H., Chagne D., McCallum J.,
RA Dzierzon H., Deng C., Wang Y.Y., Barron L., Manako K., Bowen J.,
RA Foster T.M., Erridge Z.A., Tiffin H., Waite C.N., Davies K.M.,
RA Grierson E.P., Laing W.A., Kirk R., Chen X., Wood M., Montefiori M.,
RA Brummell D.A., Schwinn K.E., Catanach A., Fullerton C., Li D.,
RA Meiyalaghan S., Nieuwenhuizen N., Read N., Prakash R., Hunter D., Zhang H.,
RA McKenzie M., Knabel M., Harris A., Allan A.C., Gleave A., Chen A.,
RA Janssen B.J., Plunkett B., Ampomah-Dwamena C., Voogd C., Leif D.,
RA Lafferty D., Souleyre E.J.F., Varkonyi-Gasic E., Gambi F., Hanley J.,
RA Yao J.L., Cheung J., David K.M., Warren B., Marsh K., Snowden K.C.,
RA Lin-Wang K., Brian L., Martinez-Sanchez M., Wang M., Ileperuma N.,
RA Macnee N., Campin R., McAtee P., Drummond R.S.M., Espley R.V.,
RA Ireland H.S., Wu R., Atkinson R.G., Karunairetnam S., Bulley S.,
RA Chunkath S., Hanley Z., Storey R., Thrimawithana A.H., Thomson S.,
RA David C., Testolin R., Huang H., Hellens R.P., Schaffer R.J.;
RT "A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome
RT highlights the challenges associated with draft genomes and gene prediction
RT in plants.";
RL BMC Genomics 19:257-257(2018).
CC -!- FUNCTION: Transcription activator involved in the spatiotemporal
CC regulation of anthocyanin biosynthesis specifically in the inner
CC pericarp of red-fleshed kiwifruits (PubMed:30912865). Functions in
CC association with BHLH42 to activate the promoters of LDOX (ANS) and
CC F3GT1 that encode the dedicated enzymes for anthocyanin biosynthesis
CC (PubMed:30912865). {ECO:0000269|PubMed:30912865}.
CC -!- SUBUNIT: Interacts with BHLH42. {ECO:0000269|PubMed:30912865}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000269|PubMed:30912865}.
CC -!- TISSUE SPECIFICITY: Expressed in the inner pericarp of maturing fruits.
CC {ECO:0000269|PubMed:30912865}.
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DR EMBL; MH643775; QAT77713.1; -; mRNA.
DR EMBL; NKQK01000024; PSR93620.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R6PN00; -.
DR SMR; A0A2R6PN00; -.
DR STRING; 1590841.A0A2R6PN00; -.
DR EnsemblPlants; PSR93620; PSR93620; CEY00_Acc28234.
DR Gramene; PSR93620; PSR93620; CEY00_Acc28234.
DR OMA; WSTSHCL; -.
DR Proteomes; UP000241394; Chromosome lg24.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031542; P:positive regulation of anthocyanin biosynthetic process; IDA:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..266
FT /note="Transcription factor MYB123"
FT /id="PRO_0000448057"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 114..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 167
FT /note="H -> P (in Ref. 1; QAT77713)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 266 AA; 30145 MW; 2E9AC14EA45E016C CRC64;
MGRSPCCSKE GLIRGAWTAV EDRTLTAYIK AHGEGKWRNL PKRAGLKRCG KSCRLRWLNY
LRPDIKRGNI SHEEEELIVR LHKLLGNRWS LIAGRLPGRT DNEIKNYWNT TLGKKIRPQT
SRESSKNNLT RKSKGKQPVI PPPPSAIRTK AVRCAKLLAP AKSPPTHGPL FLNQPVEKSF
AVLEENQSQI SKNPLLCVEN SHGTEPLEFS FHDQFHHNNG LCLEGLDDHD MVFKDWTASH
EFLEVEGNCT LDLESLASLL DCEEWP
