ID   MY14_EISFE              Reviewed;          14 AA.
AC   P46979;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   02-JUN-2021, entry version 43.
DE   RecName: Full=Myoactive tetradecapeptide;
DE            Short=ETP;
OS   Eisenia fetida (Red wiggler worm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Annelida; Clitellata;
OC   Oligochaeta; Crassiclitellata; Lumbricina; Lumbricidae; Lumbricinae;
OC   Eisenia.
OX   NCBI_TaxID=6396;
RN   [1]
RP   PROTEIN SEQUENCE, AMIDATION AT PHE-14, AND SYNTHESIS.
RC   TISSUE=Gut;
RX   PubMed=8532604; DOI=10.1016/0196-9781(95)00071-q;
RA   Ukena K., Oumi T., Matsushima O., Ikeda T., Fujita T., Minakata H.,
RA   Nomoto K.;
RT   "A novel gut tetradecapeptide isolated from the earthworm, Eisenia
RT   foetida.";
RL   Peptides 16:995-999(1995).
CC   -!- FUNCTION: Has a stimulative effect on the contraction of gut muscles.
CC   -!- SIMILARITY: To insects allatotropin. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005184; F:neuropeptide hormone activity; IEA:InterPro.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR012619; Tetradecapep.
DR   Pfam; PF08187; Tetradecapep; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide.
FT   PEPTIDE         1..14
FT                   /note="Myoactive tetradecapeptide"
FT                   /id="PRO_0000044173"
FT   MOD_RES         14
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:8532604"
SQ   SEQUENCE   14 AA;  1478 MW;  CC9ABEF941CD91AD CRC64;
     GFKDGAADRI SHGF