MYADM_PONAB
ID MYADM_PONAB Reviewed; 322 AA.
AC Q5R6H1;
DT 18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 50.
DE RecName: Full=Myeloid-associated differentiation marker;
GN Name=MYADM;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Heart;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the MAL family. {ECO:0000305}.
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DR EMBL; CR860518; CAH92645.1; -; mRNA.
DR RefSeq; NP_001126548.1; NM_001133076.1.
DR AlphaFoldDB; Q5R6H1; -.
DR SMR; Q5R6H1; -.
DR STRING; 9601.ENSPPYP00000011608; -.
DR PRIDE; Q5R6H1; -.
DR GeneID; 100173538; -.
DR KEGG; pon:100173538; -.
DR CTD; 91663; -.
DR eggNOG; KOG4788; Eukaryota.
DR InParanoid; Q5R6H1; -.
DR Proteomes; UP000001595; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR008253; Marvel.
DR Pfam; PF01284; MARVEL; 2.
DR PROSITE; PS51225; MARVEL; 2.
PE 2: Evidence at transcript level;
KW Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..322
FT /note="Myeloid-associated differentiation marker"
FT /id="PRO_0000232595"
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 31..163
FT /note="MARVEL 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
FT DOMAIN 168..319
FT /note="MARVEL 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00581"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 22
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96S97"
SQ SEQUENCE 322 AA; 35308 MW; 4EC698EE997D7342 CRC64;
MPVTVTRTTI TTTTTSSSGQ GSPTIVGSPR ALTQPLGLLR LLQLVSTCVA FSLVASVGAW
TGPMGNWSMF TWCFCFSVTL IILIVELCGL QARFPLSWRN FPITFACYAA LFCLSASIIY
PTTYVQFLSH GRSRDHAIAA TFFSCIACVA YATEVAWTRA RPGEITGYMA TVPGLLKVLE
TFVACIIFAF ISDTYLYQHQ PALEWCVAVY AICFILAAIA ILLNLGECTN VLPIPFPSFL
SGLALLSVLL YATALVLWPL YQFDEKYGGQ PRRSRDVSCS RSHAYYVCGW DRRLAVAILT
AINLLAYVAD LVHSAHLVFV KV