MYB13_ARATH
ID MYB13_ARATH Reviewed; 246 AA.
AC Q9LNC9; Q39153;
DT 10-MAY-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 169.
DE RecName: Full=Transcription factor MYB13 {ECO:0000305};
DE AltName: Full=ATMYBL1 {ECO:0000312|EMBL:CAA90748.1};
DE AltName: Full=Myb-related protein 13 {ECO:0000303|PubMed:11597504};
DE Short=AtMYB13 {ECO:0000303|PubMed:11597504};
GN Name=MYB13 {ECO:0000303|PubMed:11597504};
GN OrderedLocusNames=At1g06180 {ECO:0000312|Araport:AT1G06180};
GN ORFNames=F9P14.4 {ECO:0000312|EMBL:AAF80215.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, TISSUE SPECIFICITY, AND
RP INDUCTION.
RX PubMed=9681014; DOI=10.1046/j.1365-313x.1998.00072.x;
RA Kirik V., Koelle K., Wohlfarth T., Misera S., Baeumlein H.;
RT "Ectopic expression of a novel MYB gene modifies the architecture of the
RT Arabidopsis inflorescence.";
RL Plant J. 13:729-742(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [8]
RP FUNCTION.
RX PubMed=16861809; DOI=10.1271/bbb.60065;
RA Nozawa A., Miwa K., Kobayashi M., Fujiwara T.;
RT "Isolation of Arabidopsis thaliana cDNAs that confer yeast boric acid
RT tolerance.";
RL Biosci. Biotechnol. Biochem. 70:1724-1730(2006).
CC -!- FUNCTION: Plays a regulatory role in meristem function. Functions as
CC component of a regulatory network controlling the establishment and/or
CC development of the shoot system by the regulation of apical meristem
CC function (PubMed:9681014). May play a role in tolerance to boric acid
CC (PubMed:16861809). {ECO:0000269|PubMed:16861809,
CC ECO:0000269|PubMed:9681014}.
CC -!- INTERACTION:
CC Q9LNC9; Q9FJ98: NRPB6A; NbExp=3; IntAct=EBI-25521688, EBI-25517907;
CC Q9LNC9; Q9SJ96: NRPB6B; NbExp=3; IntAct=EBI-25521688, EBI-4429205;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- TISSUE SPECIFICITY: Expressed in roots and flowers. Expressed in shoot
CC apex, axillary buds, at the basis of flowers and branching points of
CC inflorescences. {ECO:0000269|PubMed:9681014}.
CC -!- INDUCTION: Induced by abscisic acid (ABA), drought, light and wounding
CC in leaves. Down-regulated by drought and ABA in roots.
CC {ECO:0000269|PubMed:9681014}.
CC -!- MISCELLANEOUS: Plants expressing ectopically MYB13 display peculiar
CC hook structure at pedicel branching points, and a reversed order of
CC first flowers and axillary buds. {ECO:0000269|PubMed:9681014}.
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DR EMBL; Z50869; CAA90748.1; -; Genomic_DNA.
DR EMBL; AY519550; AAS10020.1; -; mRNA.
DR EMBL; AC025290; AAF80215.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27955.1; -; Genomic_DNA.
DR EMBL; BT025173; ABE77411.1; -; mRNA.
DR EMBL; AB493437; BAH30275.1; -; mRNA.
DR PIR; D86197; D86197.
DR PIR; S71283; S71283.
DR RefSeq; NP_172108.1; NM_100499.2.
DR AlphaFoldDB; Q9LNC9; -.
DR SMR; Q9LNC9; -.
DR IntAct; Q9LNC9; 2.
DR STRING; 3702.AT1G06180.1; -.
DR PaxDb; Q9LNC9; -.
DR PRIDE; Q9LNC9; -.
DR EnsemblPlants; AT1G06180.1; AT1G06180.1; AT1G06180.
DR GeneID; 837127; -.
DR Gramene; AT1G06180.1; AT1G06180.1; AT1G06180.
DR KEGG; ath:AT1G06180; -.
DR Araport; AT1G06180; -.
DR TAIR; locus:2038520; AT1G06180.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_6_4_1; -.
DR InParanoid; Q9LNC9; -.
DR OMA; NHDMEFW; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9LNC9; -.
DR PRO; PR:Q9LNC9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LNC9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0009909; P:regulation of flower development; IMP:UniProtKB.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..246
FT /note="Transcription factor MYB13"
FT /id="PRO_0000439924"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT CONFLICT 191
FT /note="M -> T (in Ref. 1; CAA90748)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 246 AA; 27951 MW; 517450355646BD67 CRC64;
MGRRPCCEKI GLKKGPWSAE EDRILINYIS LHGHPNWRAL PKLAGLLRCG KSCRLRWINY
LRPDIKRGNF TPHEEDTIIS LHQLLGNRWS AIAAKLPGRT DNEIKNVWHT HLKKRLHHSQ
DQNNKEDFVS TTAAEMPTSP QQQSSSSADI SAITTLGNNN DISNSNKDSA TSSEDVLAII
DESFWSEVVL MDCDISGNEK NEKKIENWEG SLDRNDKGYN HDMEFWFDHL TSSSCIIGEM
SDISEF
