MYB14_ARATH
ID MYB14_ARATH Reviewed; 249 AA.
AC Q9SJX8; Q9SBG5;
DT 15-FEB-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 167.
DE RecName: Full=Transcription factor MYB14 {ECO:0000303|PubMed:9839469};
DE AltName: Full=Myb-related protein 14 {ECO:0000303|PubMed:9839469};
DE Short=AtMYB14 {ECO:0000303|PubMed:9839469};
DE Short=MYB14At {ECO:0000303|PubMed:9839469};
GN Name=MYB14 {ECO:0000303|PubMed:9839469};
GN OrderedLocusNames=At2g31180 {ECO:0000312|Araport:AT2G31180};
GN ORFNames=F16D14.2 {ECO:0000312|EMBL:AAD20663.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: A genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 84-249, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=9839469; DOI=10.1046/j.1365-313x.1998.00278.x;
RA Kranz H.D., Denekamp M., Greco R., Jin H.-L., Leyva A., Meissner R.C.,
RA Petroni K., Urzainqui A., Bevan M., Martin C., Smeekens S., Tonelli C.,
RA Paz-Ares J., Weisshaar B.;
RT "Towards functional characterisation of the members of the R2R3-MYB gene
RT family from Arabidopsis thaliana.";
RL Plant J. 16:263-276(1998).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [7]
RP INDUCTION BY SALICYLIC ACID; JASMONIC ACID; SALT; ETHYLENE AND AUXIN, AND
RP GENE FAMILY.
RX PubMed=16463103; DOI=10.1007/s11103-005-2910-y;
RA Chen Y., Yang X., He K., Liu M., Li J., Gao Z., Lin Z., Zhang Y., Wang X.,
RA Qiu X., Shen Y., Zhang L., Deng X., Luo J., Deng X.-W., Chen Z., Gu H.,
RA Qu L.-J.;
RT "The MYB transcription factor superfamily of Arabidopsis: expression
RT analysis and phylogenetic comparison with the rice MYB family.";
RL Plant Mol. Biol. 60:107-124(2006).
RN [8]
RP FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY COLD, SUBCELLULAR LOCATION,
RP TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Columbia;
RX PubMed=24415840; DOI=10.1007/s11105-012-0481-z;
RA Chen Y., Chen Z., Kang J., Kang D., Gu H., Qin G.;
RT "AtMYB14 regulates cold tolerance in Arabidopsis.";
RL Plant Mol. Biol. Rep. 31:87-97(2013).
CC -!- FUNCTION: Transcription activator that regulates freezing tolerance by
CC affecting expression of CBF genes. {ECO:0000269|PubMed:24415840}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000255|PROSITE-ProRule:PRU00768, ECO:0000269|PubMed:24415840}.
CC -!- TISSUE SPECIFICITY: Expressed in imbibed seeds, hypocotyls, cotyledons,
CC roots, seedlings, siliques and flowers. {ECO:0000269|PubMed:24415840}.
CC -!- DEVELOPMENTAL STAGE: Fades out in old roots and leaves.
CC {ECO:0000269|PubMed:24415840}.
CC -!- INDUCTION: Induced by salicylic acid (SA), jasmonic acid (JA), salt
CC (NaCl), ethylene and auxin (IAA) (PubMed:16463103). Down-regulated by
CC cold treatment (PubMed:24415840). {ECO:0000269|PubMed:16463103,
CC ECO:0000269|PubMed:24415840}.
CC -!- DISRUPTION PHENOTYPE: Increased tolerance to freezing stress and higher
CC accumulation of CBF genes and downstream genes under cold treatment.
CC {ECO:0000269|PubMed:24415840}.
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DR EMBL; AY519575; AAS10045.1; -; mRNA.
DR EMBL; AC005311; AAM15030.1; -; Genomic_DNA.
DR EMBL; AC006593; AAD20663.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08504.1; -; Genomic_DNA.
DR EMBL; BT024853; ABD60736.1; -; mRNA.
DR EMBL; AF062865; AAC83587.1; -; mRNA.
DR PIR; E84717; E84717.
DR PIR; T51637; T51637.
DR RefSeq; NP_180676.1; NM_128674.4.
DR AlphaFoldDB; Q9SJX8; -.
DR SMR; Q9SJX8; -.
DR IntAct; Q9SJX8; 12.
DR STRING; 3702.AT2G31180.1; -.
DR PaxDb; Q9SJX8; -.
DR PRIDE; Q9SJX8; -.
DR EnsemblPlants; AT2G31180.1; AT2G31180.1; AT2G31180.
DR GeneID; 817674; -.
DR Gramene; AT2G31180.1; AT2G31180.1; AT2G31180.
DR KEGG; ath:AT2G31180; -.
DR Araport; AT2G31180; -.
DR TAIR; locus:2042526; AT2G31180.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_6_4_1; -.
DR InParanoid; Q9SJX8; -.
DR OMA; QNMENIM; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9SJX8; -.
DR PRO; PR:Q9SJX8; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SJX8; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:UniProtKB.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR GO; GO:0009409; P:response to cold; IEP:UniProtKB.
DR GO; GO:0050826; P:response to freezing; IMP:UniProtKB.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..249
FT /note="Transcription factor MYB14"
FT /id="PRO_0000438896"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT MOTIF 198..205
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00768"
SQ SEQUENCE 249 AA; 28769 MW; 91AE28FF0414EE81 CRC64;
MGRAPCCEKM GVKRGPWTPE EDQILINYIH LYGHSNWRAL PKHAGLLRCG KSCRLRWINY
LRPDIKRGNF TPQEEQTIIN LHESLGNRWS AIAAKLPGRT DNEIKNVWHT HLKKRLSKNL
NNGGDTKDVN GINETTNEDK GSVIVDTASL QQFSNSITTF DISNDNKDDI MSYEDISALI
DDSFWSDVIS VDNSNKNEKK IEDWEGLIDR NSKKCSYSNS KLYNDDMEFW FDVFTSNRRI
EEFSDIPEF
