MYB1_ACTCC
ID MYB1_ACTCC Reviewed; 221 AA.
AC A0A2R6S148; A0A1P8VFB5; A0A346JM65; A0A3B8DH01; T2DL22;
DT 16-OCT-2019, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2018, sequence version 1.
DT 25-MAY-2022, entry version 17.
DE RecName: Full=Transcription factor MYB1 {ECO:0000305};
DE AltName: Full=Myb-related protein 1 {ECO:0000305};
GN Name=MYB1 {ECO:0000303|PubMed:25143057};
GN Synonyms=MYB10 {ECO:0000303|PubMed:30067292},
GN MYB75 {ECO:0000303|PubMed:29203778}, MYBF110 {ECO:0000303|PubMed:28919902};
GN ORFNames=CEY00_Acc00493 {ECO:0000312|EMBL:PSS35990.1};
OS Actinidia chinensis var. chinensis (Chinese soft-hair kiwi).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; Ericales; Actinidiaceae; Actinidia.
OX NCBI_TaxID=1590841;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=25143057; DOI=10.1111/ppl.12263;
RA Man Y.P., Wang Y.C., Li Z.Z., Jiang Z.W., Yang H.L., Gong J.J., He S.S.,
RA Wu S.Q., Yang Z.Q., Zheng J., Wang Z.Y.;
RT "High-temperature inhibition of biosynthesis and transportation of
RT anthocyanins results in the poor red coloration in red-fleshed Actinidia
RT chinensis.";
RL Physiol. Plantarum 153:565-583(2015).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=28919902; DOI=10.3389/fpls.2017.01507;
RA Liu Y., Zhou B., Qi Y., Chen X., Liu C., Liu Z., Ren X.;
RT "Expression differences of pigment structural genes and transcription
RT factors explain flesh coloration in three contrasting kiwifruit
RT cultivars.";
RL Front. Plant Sci. 8:1507-1507(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=29203778; DOI=10.1038/s41598-017-16905-1;
RA Li W., Ding Z., Ruan M., Yu X., Peng M., Liu Y.;
RT "Kiwifruit R2R3-MYB transcription factors and contribution of the novel
RT AcMYB75 to red kiwifruit anthocyanin biosynthesis.";
RL Sci. Rep. 7:16861-16861(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=30067292; DOI=10.1111/nph.15362;
RA Ampomah-Dwamena C., Thrimawithana A.H., Dejnoprat S., Lewis D.,
RA Espley R.V., Allan A.C.;
RT "A kiwifruit (Actinidia deliciosa) R2R3-MYB transcription factor modulates
RT chlorophyll and carotenoid accumulation.";
RL New Phytol. 221:309-325(2019).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Red5;
RX PubMed=29661190; DOI=10.1186/s12864-018-4656-3;
RA Pilkington S.M., Crowhurst R., Hilario E., Nardozza S., Fraser L., Peng Y.,
RA Gunaseelan K., Simpson R., Tahir J., Deroles S.C., Templeton K., Luo Z.,
RA Davy M., Cheng C., McNeilage M., Scaglione D., Liu Y., Zhang Q., Datson P.,
RA De Silva N., Gardiner S.E., Bassett H., Chagne D., McCallum J.,
RA Dzierzon H., Deng C., Wang Y.Y., Barron L., Manako K., Bowen J.,
RA Foster T.M., Erridge Z.A., Tiffin H., Waite C.N., Davies K.M.,
RA Grierson E.P., Laing W.A., Kirk R., Chen X., Wood M., Montefiori M.,
RA Brummell D.A., Schwinn K.E., Catanach A., Fullerton C., Li D.,
RA Meiyalaghan S., Nieuwenhuizen N., Read N., Prakash R., Hunter D., Zhang H.,
RA McKenzie M., Knabel M., Harris A., Allan A.C., Gleave A., Chen A.,
RA Janssen B.J., Plunkett B., Ampomah-Dwamena C., Voogd C., Leif D.,
RA Lafferty D., Souleyre E.J.F., Varkonyi-Gasic E., Gambi F., Hanley J.,
RA Yao J.L., Cheung J., David K.M., Warren B., Marsh K., Snowden K.C.,
RA Lin-Wang K., Brian L., Martinez-Sanchez M., Wang M., Ileperuma N.,
RA Macnee N., Campin R., McAtee P., Drummond R.S.M., Espley R.V.,
RA Ireland H.S., Wu R., Atkinson R.G., Karunairetnam S., Bulley S.,
RA Chunkath S., Hanley Z., Storey R., Thrimawithana A.H., Thomson S.,
RA David C., Testolin R., Huang H., Hellens R.P., Schaffer R.J.;
RT "A manually annotated Actinidia chinensis var. chinensis (kiwifruit) genome
RT highlights the challenges associated with draft genomes and gene prediction
RT in plants.";
RL BMC Genomics 19:257-257(2018).
RN [6]
RP FUNCTION.
RX PubMed=30912865; DOI=10.1111/tpj.14330;
RA Wang L., Tang W., Hu Y., Zhang Y., Sun J., Guo X., Lu H., Yang Y., Fang C.,
RA Niu X., Yue J., Fei Z., Liu Y.;
RT "A MYB/bHLH complex regulates tissue-specific anthocyanin biosynthesis in
RT the inner pericarp of red-centered kiwifruit Actinidia chinensis cv.
RT Hongyang.";
RL Plant J. 99:359-378(2019).
CC -!- FUNCTION: Transcription activator involved in the regulation of
CC anthocyanin biosynthesis in red-fleshed kiwifruit varieties
CC (PubMed:28919902, PubMed:29203778, PubMed:30912865). Activates the
CC transcription of genes involved in anthocyanin biosynthesis, such as
CC dihydroflavonol reductase (DFR), anthocyanidin synthase (ANS) and UDP
CC flavonoid glycosyltransferase (UFGT) (PubMed:28919902, PubMed:29203778,
CC PubMed:30912865). {ECO:0000269|PubMed:28919902,
CC ECO:0000269|PubMed:29203778, ECO:0000269|PubMed:30912865}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000269|PubMed:28919902, ECO:0000269|PubMed:29203778}.
CC -!- TISSUE SPECIFICITY: Expressed in stems and leaves (PubMed:25143057).
CC Expressed at low levels in ovaries (PubMed:25143057).
CC {ECO:0000269|PubMed:25143057}.
CC -!- DEVELOPMENTAL STAGE: Expressed in the inner pericarp of developing
CC fruit at 117 days after flowering (DAF). {ECO:0000269|PubMed:25143057}.
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DR EMBL; KF157390; AGV53045.1; -; mRNA.
DR EMBL; MH370827; AYJ72555.1; -; mRNA.
DR EMBL; KX349735; APZ74276.1; -; mRNA.
DR EMBL; MG581953; AXP34755.1; -; mRNA.
DR EMBL; NKQK01000001; PSS35990.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2R6S148; -.
DR SMR; A0A2R6S148; -.
DR STRING; 1590841.A0A2R6S148; -.
DR EnsemblPlants; PSS35990; PSS35990; CEY00_Acc00493.
DR Gramene; PSS35990; PSS35990; CEY00_Acc00493.
DR Proteomes; UP000241394; Chromosome lg1.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031542; P:positive regulation of anthocyanin biosynthetic process; IDA:UniProtKB.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..221
FT /note="Transcription factor MYB1"
FT /id="PRO_0000448058"
FT DOMAIN 1..57
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 58..112
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 33..57
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 85..108
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 126..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 17
FT /note="E -> G (in Ref. 1; AGV53045)"
FT /evidence="ECO:0000305"
FT CONFLICT 115
FT /note="Y -> S (in Ref. 2; AYJ72555)"
FT /evidence="ECO:0000305"
FT CONFLICT 119
FT /note="Q -> E (in Ref. 2; AYJ72555)"
FT /evidence="ECO:0000305"
FT CONFLICT 192
FT /note="A -> P (in Ref. 2; AYJ72555 and 1; AGV53045)"
FT /evidence="ECO:0000305"
FT CONFLICT 215
FT /note="W -> R (in Ref. 2; AYJ72555 and 3; APZ74276)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 221 AA; 25471 MW; 20E610B34A39E1B6 CRC64;
MESVTLGVRK GAWTEEEDKL LKKCIEKYGE GKWHQVPLRS GLNRCRKSCR MRWLNYLRPN
INRGNFTADE VDLIIRLHKL LGNRWSLIAG RLPGRTSNDV KNYWNTHLQK KLITYPRAQP
IPKTQKTIVP KGTEAQPRAH PKSPPRPSPP SNNEILWWDN KTVSPQIDNI GIHWSIDGSI
FEEPILGNLQ SAGDSFLQQN QSDWSDIFLE DVNLWDLLGD D
