ID   MYB1_NEUCR              Reviewed;         324 AA.
AC   O13493; Q1K7V6; Q9HEF2;
DT   30-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 2.
DT   25-MAY-2022, entry version 125.
DE   RecName: Full=Myb-like DNA-binding protein myb-1;
GN   Name=rca-1; Synonyms=myb-1; ORFNames=65E11.140, NCU01312;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   PubMed=9539422; DOI=10.1093/genetics/148.3.1031;
RA   Shen W.-C., Wieser J., Adams T.H., Ebbole D.J.;
RT   "The Neurospora rca-1 gene complements an Aspergillus flbD sporulation
RT   mutant but has no identifiable role in Neurospora sporulation.";
RL   Genetics 148:1031-1041(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12655011; DOI=10.1093/nar/gkg293;
RA   Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., Hoheisel J.D.,
RA   Fartmann B., Nyakatura G., Kempken F., Maier J., Schulte U.;
RT   "What's in the genome of a filamentous fungus? Analysis of the Neurospora
RT   genome sequence.";
RL   Nucleic Acids Res. 31:1944-1954(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB62897.1; Type=Frameshift; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF006202; AAB62897.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AL451021; CAC18298.1; -; Genomic_DNA.
DR   EMBL; CM002240; EAA32162.1; -; Genomic_DNA.
DR   PIR; T47227; T47227.
DR   RefSeq; XP_961398.1; XM_956305.3.
DR   AlphaFoldDB; O13493; -.
DR   SMR; O13493; -.
DR   STRING; 5141.EFNCRP00000004118; -.
DR   EnsemblFungi; EAA32162; EAA32162; NCU01312.
DR   GeneID; 3877542; -.
DR   KEGG; ncr:NCU01312; -.
DR   VEuPathDB; FungiDB:NCU01312; -.
DR   HOGENOM; CLU_046302_0_0_1; -.
DR   InParanoid; O13493; -.
DR   OMA; HESIEWF; -.
DR   Proteomes; UP000001805; Chromosome 2, Linkage Group V.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   CDD; cd00167; SANT; 2.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017930; Myb_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   Pfam; PF00249; Myb_DNA-binding; 2.
DR   SMART; SM00717; SANT; 2.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS51294; HTH_MYB; 2.
PE   3: Inferred from homology;
KW   DNA-binding; Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..324
FT                   /note="Myb-like DNA-binding protein myb-1"
FT                   /id="PRO_0000197086"
FT   DOMAIN          4..59
FT                   /note="HTH myb-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DOMAIN          60..110
FT                   /note="HTH myb-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   REGION          107..231
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        107..130
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        178..231
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   324 AA;  36540 MW;  A45A5D088C06DA3F CRC64;
     MSNMPDQRRG PWSAGEDQRL IKLVKDLGPG NWVNVARILG TRTPKQCRER WHQNLKPGLN
     HGPMTQEEAA IIVREVDLKG PRWADIARKL QGRSDNAVKN YWNGLNNRKK NQLRRQSAPR
     RVSASDVLRS SPGQLPRAHM QRPIRYPQDI YTGSRRPSSP SSFNDSLHHR VHESIEWFPS
     RPQQQQQQQQ QQARCTTPFT SFYPPSHAFP TTDGYQDGSD GPTGSTLRLL TPPTSRRLAP
     FSTLPSPTTS SIGDLDEFDR RQLAAFAPPA AYRRPSLPFP QQSSMGYLPS ATEYLPTAPS
     SPIALIQRDE KNHARIPVTS LLCS