MYB24_ARATH
ID MYB24_ARATH Reviewed; 214 AA.
AC Q9SPG9; Q8LCG0;
DT 11-DEC-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 158.
DE RecName: Full=Transcription factor MYB24;
DE AltName: Full=Myb-related protein 24;
DE Short=AtMYB24;
GN Name=MYB24; OrderedLocusNames=At5g40350; ORFNames=MPO12.60;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=9839469; DOI=10.1046/j.1365-313x.1998.00278.x;
RA Kranz H.D., Denekamp M., Greco R., Jin H.-L., Leyva A., Meissner R.C.,
RA Petroni K., Urzainqui A., Bevan M., Martin C., Smeekens S., Tonelli C.,
RA Paz-Ares J., Weisshaar B.;
RT "Towards functional characterisation of the members of the R2R3-MYB gene
RT family from Arabidopsis thaliana.";
RL Plant J. 16:263-276(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY JASMONATE, AND TISSUE
RP SPECIFICITY.
RX PubMed=16805732; DOI=10.1111/j.1365-313x.2006.02756.x;
RA Mandaokar A., Thines B., Shin B., Lange B.M., Choi G., Koo Y.J., Yoo Y.J.,
RA Choi Y.D., Choi G., Browse J.;
RT "Transcriptional regulators of stamen development in Arabidopsis identified
RT by transcriptional profiling.";
RL Plant J. 46:984-1008(2006).
RN [8]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RX PubMed=16972096; DOI=10.1007/s00299-006-0229-z;
RA Yang X.Y., Li J.G., Pei M., Gu H., Chen Z.L., Qu L.J.;
RT "Over-expression of a flower-specific transcription factor gene AtMYB24
RT causes aberrant anther development.";
RL Plant Cell Rep. 26:219-228(2007).
RN [9]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=19091873; DOI=10.1104/pp.108.132597;
RA Mandaokar A., Browse J.;
RT "MYB108 acts together with MYB24 to regulate jasmonate-mediated stamen
RT maturation in Arabidopsis.";
RL Plant Physiol. 149:851-862(2009).
RN [10]
RP FUNCTION, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=19325888; DOI=10.1371/journal.pgen.1000440;
RA Cheng H., Song S., Xiao L., Soo H.M., Cheng Z., Xie D., Peng J.;
RT "Gibberellin acts through jasmonate to control the expression of MYB21,
RT MYB24, and MYB57 to promote stamen filament growth in Arabidopsis.";
RL PLoS Genet. 5:E1000440-E1000440(2009).
RN [11]
RP FUNCTION, AND INTERACTION WITH TIFY10A/JAZ1; TIFY5A/JAZ8 AND TIFY3A/JAZ11.
RX PubMed=21447791; DOI=10.1105/tpc.111.083089;
RA Song S., Qi T., Huang H., Ren Q., Wu D., Chang C., Peng W., Liu Y.,
RA Peng J., Xie D.;
RT "The Jasmonate-ZIM domain proteins interact with the R2R3-MYB transcription
RT factors MYB21 and MYB24 to affect Jasmonate-regulated stamen development in
RT Arabidopsis.";
RL Plant Cell 23:1000-1013(2011).
CC -!- FUNCTION: Transcription factor acting redundantly with MYB21 and MYB57
CC to control stamen filament elongation in the late developed flowers.
CC Contributes with MYB21 to induction of MYB108 by jasmonate. Repressed
CC at the transcript levels by DELLA proteins.
CC {ECO:0000269|PubMed:16805732, ECO:0000269|PubMed:16972096,
CC ECO:0000269|PubMed:19091873, ECO:0000269|PubMed:19325888,
CC ECO:0000269|PubMed:21447791}.
CC -!- SUBUNIT: Interacts (via N-terminus) with TIFY10A/JAZ1, TIFY5A/JAZ8 AND
CC TIFY3A/JAZ11. {ECO:0000269|PubMed:21447791}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000269|PubMed:16972096}.
CC -!- TISSUE SPECIFICITY: Expressed specifically in flowers. Expressed in all
CC four whorls of the flower and in the vascular tissue of stamen filament
CC and sepals. Detected in male and female gametophytes, especially in
CC microspores and ovules. Weakly expressed in petals and the upper part
CC of pistils. {ECO:0000269|PubMed:16805732, ECO:0000269|PubMed:16972096,
CC ECO:0000269|PubMed:19325888}.
CC -!- DEVELOPMENTAL STAGE: Tightly regulated during anther development.
CC {ECO:0000269|PubMed:16972096}.
CC -!- INDUCTION: Up-regulated by jasmonate. {ECO:0000269|PubMed:16805732}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype. Myb24 and myb57 double
CC mutant has petals that grew to a final height parallel to the pistil.
CC Myb21 and myb24 double mutant is partially sterile and has petals that
CC just grew out of the sepals but ended at a lower level than the stigma.
CC Myb21, myb24 and myb57 triple mutant has a strongly reduced fertility
CC and an arrested growth of the petals that never grew out of the sepals.
CC Myb24 and myb108 double mutant has a reduced fertility and a greatly
CC reduced seed set. {ECO:0000269|PubMed:16805732,
CC ECO:0000269|PubMed:19091873, ECO:0000269|PubMed:19325888}.
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DR EMBL; AF175987; AAD53092.1; -; mRNA.
DR EMBL; AY519632; AAS10102.1; -; mRNA.
DR EMBL; AB006702; BAB11590.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94536.1; -; Genomic_DNA.
DR EMBL; AY086615; AAM63674.1; -; mRNA.
DR RefSeq; NP_198851.1; NM_123399.4.
DR AlphaFoldDB; Q9SPG9; -.
DR SMR; Q9SPG9; -.
DR BioGRID; 19284; 9.
DR STRING; 3702.AT5G40350.1; -.
DR PaxDb; Q9SPG9; -.
DR PRIDE; Q9SPG9; -.
DR ProteomicsDB; 251368; -.
DR EnsemblPlants; AT5G40350.1; AT5G40350.1; AT5G40350.
DR GeneID; 834033; -.
DR Gramene; AT5G40350.1; AT5G40350.1; AT5G40350.
DR KEGG; ath:AT5G40350; -.
DR Araport; AT5G40350; -.
DR TAIR; locus:2170573; AT5G40350.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_25_8_1; -.
DR InParanoid; Q9SPG9; -.
DR OMA; AEMFSFN; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9SPG9; -.
DR PRO; PR:Q9SPG9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9SPG9; baseline and differential.
DR Genevisible; Q9SPG9; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:1990841; F:promoter-specific chromatin binding; IPI:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0009740; P:gibberellic acid mediated signaling pathway; IEP:TAIR.
DR GO; GO:0009867; P:jasmonic acid mediated signaling pathway; IEP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR GO; GO:0009753; P:response to jasmonic acid; IEP:TAIR.
DR GO; GO:0048443; P:stamen development; IMP:TAIR.
DR GO; GO:0080086; P:stamen filament development; IGI:TAIR.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR044676; EOBI/EOBII-like_plant.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR PANTHER; PTHR45675; PTHR45675; 1.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..214
FT /note="Transcription factor MYB24"
FT /id="PRO_0000424710"
FT DOMAIN 14..66
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 67..121
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 42..66
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 94..117
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT CONFLICT 184
FT /note="G -> S (in Ref. 6; AAM63674)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 214 AA; 24459 MW; B5DAE2471F75673F CRC64;
MEKRESSGGS GSGDAEVRKG PWTMEEDLIL INYIANHGEG VWNSLAKSAG LKRTGKSCRL
RWLNYLRPDV RRGNITPEEQ LTIMELHAKW GNRWSKIAKH LPGRTDNEIK NFWRTKIQKY
IIKSGETTTV GSQSSEFINH HATTSHVMND TQETMDMYSP TTSYQHASNI NQQLNYGNYV
PESGSIMMPL SVDQSEQNYW SVDDLWPMNI YNGN
