MYB26_ARATH
ID MYB26_ARATH Reviewed; 367 AA.
AC Q9SPG3; A0MEW0; Q9LVL0;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 166.
DE RecName: Full=Transcription factor MYB26 {ECO:0000305};
DE AltName: Full=Myb-related protein 26 {ECO:0000305};
DE Short=AtMYB26 {ECO:0000303|PubMed:11597504};
DE AltName: Full=Protein MALE STERILE 35 {ECO:0000303|PubMed:12753590};
GN Name=MYB26 {ECO:0000303|PubMed:11597504};
GN Synonyms=MS35 {ECO:0000303|PubMed:12753590};
GN OrderedLocusNames=At3g13890 {ECO:0000312|Araport:AT3G13890};
GN ORFNames=MDC16.1 {ECO:0000312|EMBL:BAB02319.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [6]
RP FUNCTION, TISSUE SPECIFICITY, AND DISRUPTION PHENOTYPE.
RX PubMed=12753590; DOI=10.1046/j.1365-313x.2003.01745.x;
RA Steiner-Lange S., Unte U.S., Eckstein L., Yang C., Wilson Z.A.,
RA Schmelzer E., Dekker K., Saedler H.;
RT "Disruption of Arabidopsis thaliana MYB26 results in male sterility due to
RT non-dehiscent anthers.";
RL Plant J. 34:519-528(2003).
RN [7]
RP FUNCTION.
RX PubMed=17147638; DOI=10.1111/j.1467-7652.2006.00184.x;
RA Mitsuda N., Hiratsu K., Todaka D., Nakashima K., Yamaguchi-Shinozaki K.,
RA Ohme-Takagi M.;
RT "Efficient production of male and female sterile plants by expression of a
RT chimeric repressor in Arabidopsis and rice.";
RL Plant Biotechnol. J. 4:325-332(2006).
RN [8]
RP FUNCTION, SUBCELLULAR LOCATION, AND DEVELOPMENTAL STAGE.
RX PubMed=17329564; DOI=10.1105/tpc.106.046391;
RA Yang C., Xu Z., Song J., Conner K., Vizcay Barrena G., Wilson Z.A.;
RT "Arabidopsis MYB26/MALE STERILE35 regulates secondary thickening in the
RT endothecium and is essential for anther dehiscence.";
RL Plant Cell 19:534-548(2007).
RN [9]
RP INDUCTION.
RX PubMed=23410518; DOI=10.1111/tpj.12130;
RA Cecchetti V., Altamura M.M., Brunetti P., Petrocelli V., Falasca G.,
RA Ljung K., Costantino P., Cardarelli M.;
RT "Auxin controls Arabidopsis anther dehiscence by regulating endothecium
RT lignification and jasmonic acid biosynthesis.";
RL Plant J. 74:411-422(2013).
CC -!- FUNCTION: Probable transcription factor that regulates lignified
CC secondary cell wall thickening of the anther endocethium, which is
CC necessary for anther dehiscence (PubMed:12753590, PubMed:17147638,
CC PubMed:17329564). May play a role in specifying early endothecial cell
CC development by regulating a number of genes linked to secondary
CC thickening such as NST1 and NST2. Acts upstream of the lignin
CC biosynthesis pathway (PubMed:17329564). {ECO:0000269|PubMed:12753590,
CC ECO:0000269|PubMed:17147638, ECO:0000269|PubMed:17329564}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:17329564}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9SPG3-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9SPG3-2; Sequence=VSP_057673;
CC -!- TISSUE SPECIFICITY: Highly expressed in flowers.
CC {ECO:0000269|PubMed:12753590}.
CC -!- DEVELOPMENTAL STAGE: Expressed in anthers early during endothecial
CC development, with maximal expression during pollen mitosis I and
CC bicellular stages. {ECO:0000269|PubMed:17329564}.
CC -!- INDUCTION: Down-regulated by auxin. {ECO:0000269|PubMed:23410518}.
CC -!- DISRUPTION PHENOTYPE: Male sterility due to a defect in anther
CC dehiscence. Fertile pollen. {ECO:0000269|PubMed:12753590}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28557.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF175997; AAD53102.1; -; mRNA.
DR EMBL; AY519588; AAS10058.1; -; mRNA.
DR EMBL; AB019229; BAB02319.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75433.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75434.1; -; Genomic_DNA.
DR EMBL; DQ446661; ABE65939.1; -; mRNA.
DR EMBL; DQ653083; ABK28557.1; ALT_SEQ; mRNA.
DR RefSeq; NP_001078147.1; NM_001084678.2. [Q9SPG3-2]
DR RefSeq; NP_566467.2; NM_112243.3. [Q9SPG3-1]
DR AlphaFoldDB; Q9SPG3; -.
DR SMR; Q9SPG3; -.
DR STRING; 3702.AT3G13890.1; -.
DR PaxDb; Q9SPG3; -.
DR PRIDE; Q9SPG3; -.
DR EnsemblPlants; AT3G13890.1; AT3G13890.1; AT3G13890. [Q9SPG3-1]
DR EnsemblPlants; AT3G13890.2; AT3G13890.2; AT3G13890. [Q9SPG3-2]
DR GeneID; 820602; -.
DR Gramene; AT3G13890.1; AT3G13890.1; AT3G13890. [Q9SPG3-1]
DR Gramene; AT3G13890.2; AT3G13890.2; AT3G13890. [Q9SPG3-2]
DR KEGG; ath:AT3G13890; -.
DR Araport; AT3G13890; -.
DR TAIR; locus:2088187; AT3G13890.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_1_0_1; -.
DR InParanoid; Q9SPG3; -.
DR OMA; FIANTNP; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9SPG3; -.
DR PRO; PR:Q9SPG3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SPG3; baseline and differential.
DR Genevisible; Q9SPG3; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009834; P:plant-type secondary cell wall biogenesis; IMP:TAIR.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..367
FT /note="Transcription factor MYB26"
FT /id="PRO_0000433126"
FT DOMAIN 9..70
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 71..125
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..70
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 98..121
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT VAR_SEQ 46..54
FT /note="Missing (in isoform 2)"
FT /id="VSP_057673"
SQ SEQUENCE 367 AA; 41576 MW; 4E6A1E7CC6424541 CRC64;
MGHHSCCNKQ KVKRGLWSPE EDEKLINYIN SYGHGCWSSV PKHAGTYTHI HGFCLQRCGK
SCRLRWINYL RPDLKRGSFS PQEAALIIEL HSILGNRWAQ IAKHLPGRTD NEVKNFWNSS
IKKKLMSHHH HGHHHHHLSS MASLLTNLPY HNGFNPTTVD DESSRFMSNI ITNTNPNFIT
PSHLSLPSPH VMTPLMFPTS REGDFKFLTT NNPNQSHHHD NNHYNNLDIL SPTPTINNHH
QPSLSSCPHD NNLQWPALPD FPASTISGFQ ETLQDYDDAN KLNVFVTPFN DNAKKLLCGE
VLEGKVLSSS SPISQDHGLF LPTTYNFQMT STSDHQHHHR VDSYINHMII PSSSSSSPIS
CGQYVIT
