MYB4_ORYSJ
ID MYB4_ORYSJ Reviewed; 257 AA.
AC Q7XBH4; O04140; Q0JBQ5; Q7XKW3; Q8SA75;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Transcription factor MYB4 {ECO:0000305};
DE AltName: Full=Myb-related protein 4 {ECO:0000305};
DE Short=OsMyb4 {ECO:0000303|PubMed:14675437};
DE AltName: Full=Transcription factor RLTR1 {ECO:0000312|EMBL:AAP92750.1};
GN Name=MYB4 {ECO:0000303|PubMed:14675437};
GN Synonyms=LTR1 {ECO:0000312|EMBL:AAP92750.1};
GN OrderedLocusNames=Os04g0517100 {ECO:0000312|EMBL:BAF15232.1},
GN LOC_Os04g43680 {ECO:0000305};
GN ORFNames=OsJ_15470 {ECO:0000312|EMBL:EAZ31348.1},
GN OSJNBa0073E02.6 {ECO:0000312|EMBL:CAE05446.2};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Arborio; TISSUE=Coleoptile;
RA Solinas G., Valle G., Pandolfi D., Coraggio I.;
RT "Cloning of a cDNA encoding a novel myb gene highly expressed in
RT anaerobically germinated rice coleoptiles.";
RL (er) Plant Gene Register PGR97-078(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], AND INDUCTION.
RC STRAIN=cv. Arborio; TISSUE=Coleoptile;
RA Pandolfi D., Solinas G., Valle G., Coraggio I.;
RT "Cloning of a cDNA encoding a novel myb gene highly expressed in cold
RT stressed rice coleoptiles.";
RL (er) Plant Gene Register PGR97-079(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Quanhong Y., Rihe P., Aisheng X.;
RT "MYB-family protein acts as a signal transporter in JA induced
RT resistance.";
RL Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [7]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [9]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-159.
RA Yao Q., Peng R., Xiong A., Li X., Fan H.;
RL Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
RN [10]
RP FUNCTION, AND INDUCTION.
RX PubMed=14675437; DOI=10.1046/j.1365-313x.2003.01938.x;
RA Vannini C., Locatelli F., Bracale M., Magnani E., Marsoni M., Osnato M.,
RA Mattana M., Baldoni E., Coraggio I.;
RT "Overexpression of the rice Osmyb4 gene increases chilling and freezing
RT tolerance of Arabidopsis thaliana plants.";
RL Plant J. 37:115-127(2004).
RN [11]
RP FUNCTION, AND INDUCTION.
RX PubMed=20807373; DOI=10.1111/j.1365-3040.2010.02221.x;
RA Park M.R., Yun K.Y., Mohanty B., Herath V., Xu F., Wijaya E., Bajic V.B.,
RA Yun S.J., De Los Reyes B.G.;
RT "Supra-optimal expression of the cold-regulated OsMyb4 transcription factor
RT in transgenic rice changes the complexity of transcriptional network with
RT major effects on stress tolerance and panicle development.";
RL Plant Cell Environ. 33:2209-2230(2010).
RN [12]
RP FUNCTION.
RX PubMed=22246661; DOI=10.1007/s13353-011-0081-x;
RA Soltesz A., Vagujfalvi A., Rizza F., Kerepesi I., Galiba G., Cattivelli L.,
RA Coraggio I., Crosatti C.;
RT "The rice Osmyb4 gene enhances tolerance to frost and improves germination
RT under unfavourable conditions in transgenic barley plants.";
RL J. Appl. Genet. 53:133-143(2012).
CC -!- FUNCTION: Transcriptional activator involved in cold stress response
CC (PubMed:14675437, PubMed:20807373, PubMed:22246661). Regulates
CC positively the expression of genes involved in reactive oxygen species
CC (ROS) scavenging such as peroxidase and superoxide dismutase during
CC cold stress. Transactivates a complex gene network that have major
CC effects on stress tolerance and panicle development (PubMed:20807373).
CC {ECO:0000269|PubMed:14675437, ECO:0000269|PubMed:20807373,
CC ECO:0000269|PubMed:22246661}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- INDUCTION: By cold stress. {ECO:0000269|PubMed:14675437,
CC ECO:0000269|PubMed:20807373, ECO:0000269|Ref.2}.
CC -!- MISCELLANEOUS: Arabidopsis plants overexpressing MYB4 show dwarf
CC phenotype and increased tolerance to cold and freezing
CC (PubMed:14675437). Barley plants overexpressing MYB4 show a slight
CC retarded growth and increased tolerance to cold and freezing
CC (PubMed:22246661). {ECO:0000269|PubMed:14675437,
CC ECO:0000269|PubMed:22246661}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAL78372.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; Y11414; CAA72217.1; -; mRNA.
DR EMBL; AY323484; AAP92750.1; -; mRNA.
DR EMBL; AL731616; CAE05446.2; -; Genomic_DNA.
DR EMBL; AP008210; BAF15232.1; -; Genomic_DNA.
DR EMBL; AP014960; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CM000141; EAZ31348.1; -; Genomic_DNA.
DR EMBL; AF467733; AAL78372.1; ALT_FRAME; mRNA.
DR PIR; T03825; T03825.
DR RefSeq; XP_015633465.1; XM_015777979.1.
DR AlphaFoldDB; Q7XBH4; -.
DR SMR; Q7XBH4; -.
DR STRING; 4530.OS04T0517100-01; -.
DR PaxDb; Q7XBH4; -.
DR PRIDE; Q7XBH4; -.
DR EnsemblPlants; Os04t0517100-02; Os04t0517100-02; Os04g0517100.
DR GeneID; 4336407; -.
DR Gramene; Os04t0517100-02; Os04t0517100-02; Os04g0517100.
DR KEGG; osa:4336407; -.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_6_4_1; -.
DR InParanoid; Q7XBH4; -.
DR OrthoDB; 1499244at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000007752; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR ExpressionAtlas; Q7XBH4; baseline and differential.
DR Genevisible; Q7XBH4; OS.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR GO; GO:0009409; P:response to cold; IMP:UniProtKB.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Stress response;
KW Transcription; Transcription regulation.
FT CHAIN 1..257
FT /note="Transcription factor MYB4"
FT /id="PRO_0000197080"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 115..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 138..159
FT /note="SAKKPAAAAAAPPASPERSASS -> TRRSQPPPPPGRGVAERSARRR (in
FT Ref. 9; AAL78372)"
FT /evidence="ECO:0000305"
FT CONFLICT 152
FT /note="S -> L (in Ref. 3; AAP92750)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 257 AA; 27914 MW; E2B602B89FC9BC37 CRC64;
MGRAPCCEKM GLKKGPWTPE EDKVLVAHIQ RHGHGNWRAL PKQAGLLRCG KSCRLRWINY
LRPDIKRGNF SKEEEDTIIH LHELLGNRWS AIAARLPGRT DNEIKNVWHT HLKKRLDAPA
QGGHVAASGG KKHKKPKSAK KPAAAAAAPP ASPERSASSS VTESSMASSV AEEHGNAGIS
SASASVCAKE ESSFTSASEE FQIDDSFWSE TLSMPLDGYD VSMEPGDAFV APPSADDMDY
WLGVFMESGE AQDLPQI
