MYB53_ARATH
ID MYB53_ARATH Reviewed; 310 AA.
AC Q9FJP2; Q9ZTD8;
DT 31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 161.
DE RecName: Full=Transcription factor MYB53 {ECO:0000303|PubMed:9839469};
DE AltName: Full=Myb-related protein 53 {ECO:0000303|PubMed:9839469};
DE Short=AtMYB53 {ECO:0000303|PubMed:9839469};
GN Name=MYB53 {ECO:0000303|PubMed:9839469};
GN OrderedLocusNames=At5g65230 {ECO:0000312|Araport:AT5G65230};
GN ORFNames=MQN23.17 {ECO:0000312|EMBL:BAB11659.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: A genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 78-310, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=9839469; DOI=10.1046/j.1365-313x.1998.00278.x;
RA Kranz H.D., Denekamp M., Greco R., Jin H.-L., Leyva A., Meissner R.C.,
RA Petroni K., Urzainqui A., Bevan M., Martin C., Smeekens S., Tonelli C.,
RA Paz-Ares J., Weisshaar B.;
RT "Towards functional characterisation of the members of the R2R3-MYB gene
RT family from Arabidopsis thaliana.";
RL Plant J. 16:263-276(1998).
RN [5]
RP INTERACTION WITH FBX5, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=24902892; DOI=10.1111/nph.12879;
RA Gibbs D.J., Voss U., Harding S.A., Fannon J., Moody L.A., Yamada E.,
RA Swarup K., Nibau C., Bassel G.W., Choudhary A., Lavenus J., Bradshaw S.J.,
RA Stekel D.J., Bennett M.J., Coates J.C.;
RT "AtMYB93 is a novel negative regulator of lateral root development in
RT Arabidopsis.";
RL New Phytol. 203:1194-1207(2014).
CC -!- FUNCTION: Probable transcription factor.
CC {ECO:0000250|UniProtKB:Q9M2D9}.
CC -!- SUBUNIT: Interacts with FBX5. {ECO:0000269|PubMed:24902892}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- TISSUE SPECIFICITY: Highly expressed in roots and at lower levels in
CC leaves, stems and flowers. {ECO:0000269|PubMed:24902892}.
CC -!- INDUCTION: Induced by abscisic acid (ABA) and gravity in roots.
CC {ECO:0000269|PubMed:24902892}.
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DR EMBL; AY519646; AAS10116.1; -; mRNA.
DR EMBL; AB013395; BAB11659.1; -; Genomic_DNA.
DR EMBL; CP002688; AED98026.1; -; Genomic_DNA.
DR EMBL; AF062889; AAC83611.1; -; mRNA.
DR PIR; T51661; T51661.
DR RefSeq; NP_201326.1; NM_125921.3.
DR AlphaFoldDB; Q9FJP2; -.
DR SMR; Q9FJP2; -.
DR STRING; 3702.AT5G65230.1; -.
DR PaxDb; Q9FJP2; -.
DR PRIDE; Q9FJP2; -.
DR EnsemblPlants; AT5G65230.1; AT5G65230.1; AT5G65230.
DR GeneID; 836648; -.
DR Gramene; AT5G65230.1; AT5G65230.1; AT5G65230.
DR KEGG; ath:AT5G65230; -.
DR Araport; AT5G65230; -.
DR TAIR; locus:2171845; AT5G65230.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_15_4_1; -.
DR InParanoid; Q9FJP2; -.
DR OMA; TLEENHF; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9FJP2; -.
DR PRO; PR:Q9FJP2; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FJP2; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..310
FT /note="Transcription factor MYB53"
FT /id="PRO_0000442925"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT CONFLICT 224
FT /note="N -> S (in Ref. 4; AAC83611)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 310 AA; 35136 MW; 9070DD86A4C2AF9D CRC64;
MGRSPSSDET GLKKGPWLPE EDDKLINYIH KHGHSSWSAL PKLAGLNRCG KSCRLRWTNY
LRPDIKRGKF SAEEEETILN LHAVLGNKWS MIASHLPGRT DNEIKNFWNT HLKKKLIQMG
FDPMTHQPRT DDIFSSLSQL MSLSNLRGLV DLQQQFPMED QALLNLQTEM AKLQLFQYLL
QPSPAPMSIN NINPNILNLL IKENSVTSNI DLGFLSSHLQ DFNNNNLPSL KTLDDNHFSQ
NTSPIWLHEP PSLNQTMLPT HDPCAQSVDG FGSNQASSSH DQEVAVTDSV DWPDHHLFDD
SMFPDISYQS
