MYB54_ARATH
ID MYB54_ARATH Reviewed; 243 AA.
AC Q9FX36; Q9ZTD7;
DT 31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 168.
DE RecName: Full=Transcription factor MYB54 {ECO:0000303|PubMed:9839469};
DE AltName: Full=Myb-related protein 54 {ECO:0000303|PubMed:9839469};
DE Short=AtMYB54 {ECO:0000303|PubMed:9839469};
GN Name=MYB54 {ECO:0000303|PubMed:9839469};
GN OrderedLocusNames=At1g73410 {ECO:0000312|Araport:AT1G73410};
GN ORFNames=T9L24.38 {ECO:0000312|EMBL:AAG30986.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=9839469; DOI=10.1046/j.1365-313x.1998.00278.x;
RA Kranz H.D., Denekamp M., Greco R., Jin H.-L., Leyva A., Meissner R.C.,
RA Petroni K., Urzainqui A., Bevan M., Martin C., Smeekens S., Tonelli C.,
RA Paz-Ares J., Weisshaar B.;
RT "Towards functional characterisation of the members of the R2R3-MYB gene
RT family from Arabidopsis thaliana.";
RL Plant J. 16:263-276(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: A genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=18952777; DOI=10.1105/tpc.108.061325;
RA Zhong R., Lee C., Zhou J., McCarthy R.L., Ye Z.H.;
RT "A battery of transcription factors involved in the regulation of secondary
RT cell wall biosynthesis in Arabidopsis.";
RL Plant Cell 20:2763-2782(2008).
CC -!- FUNCTION: Transcription factor that regulates secondary cell wall (SCW)
CC biosynthesis, especially in interfascicular and xylary fibers.
CC {ECO:0000269|PubMed:18952777}.
CC -!- INTERACTION:
CC Q9FX36; Q9FIW5: ANAC094; NbExp=3; IntAct=EBI-25511270, EBI-25522986;
CC Q9FX36; Q93YR9: ARF16; NbExp=3; IntAct=EBI-25511270, EBI-3947588;
CC Q9FX36; A0A178VXH5: At2g43220; NbExp=4; IntAct=EBI-25511270, EBI-25511288;
CC Q9FX36; Q94AW5: ERF003; NbExp=3; IntAct=EBI-25511270, EBI-15202166;
CC Q9FX36; Q3E703: ERF088; NbExp=3; IntAct=EBI-25511270, EBI-15200258;
CC Q9FX36; Q9SK67: ERF120; NbExp=3; IntAct=EBI-25511270, EBI-25515179;
CC Q9FX36; Q9FYK5: ESR2; NbExp=4; IntAct=EBI-25511270, EBI-1536925;
CC Q9FX36; Q9LQT8: GAI; NbExp=3; IntAct=EBI-25511270, EBI-963606;
CC Q9FX36; P46639: KNAT1; NbExp=5; IntAct=EBI-25511270, EBI-530486;
CC Q9FX36; Q9SJW5: LBD14; NbExp=3; IntAct=EBI-25511270, EBI-25522919;
CC Q9FX36; O23160: MYB73; NbExp=3; IntAct=EBI-25511270, EBI-25506855;
CC Q9FX36; Q9S9Z2: MYB93; NbExp=3; IntAct=EBI-25511270, EBI-15202792;
CC Q9FX36; Q8GXW1: RGL2; NbExp=3; IntAct=EBI-25511270, EBI-963665;
CC Q9FX36; Q9LF53: RGL3; NbExp=3; IntAct=EBI-25511270, EBI-15681313;
CC Q9FX36; Q9FHZ1: SCL23; NbExp=3; IntAct=EBI-25511270, EBI-1238460;
CC Q9FX36; Q9LQF0: TCP23; NbExp=3; IntAct=EBI-25511270, EBI-15192297;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000269|PubMed:18952777}.
CC -!- TISSUE SPECIFICITY: In elongating stem internodes, expressed in
CC developing protoxylem and elongating interfascicular fiber cells. In
CC non-elongating internodes, expressed in developing metaxylem cells and
CC interfascicular fibers. In roots, expressed in developing secondary
CC xylem. {ECO:0000269|PubMed:18952777}.
CC -!- MISCELLANEOUS: Plants silencing MYB54 exhibit secondary cell wall (SCW)
CC defects including severe reduction in SCW thickening in both
CC interfascicular fibers and xylary fibers of inflorescence stems.
CC {ECO:0000269|PubMed:18952777}.
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DR EMBL; AF062890; AAC83612.1; -; mRNA.
DR EMBL; AY519569; AAS10039.1; -; mRNA.
DR EMBL; AC012396; AAG30986.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35458.1; -; Genomic_DNA.
DR EMBL; BT024851; ABD60734.1; -; mRNA.
DR EMBL; AK227402; BAE99406.1; -; mRNA.
DR PIR; G96760; G96760.
DR PIR; T51662; T51662.
DR RefSeq; NP_177484.1; NM_106001.3.
DR AlphaFoldDB; Q9FX36; -.
DR SMR; Q9FX36; -.
DR IntAct; Q9FX36; 16.
DR STRING; 3702.AT1G73410.1; -.
DR PaxDb; Q9FX36; -.
DR PRIDE; Q9FX36; -.
DR ProteomicsDB; 251216; -.
DR EnsemblPlants; AT1G73410.1; AT1G73410.1; AT1G73410.
DR GeneID; 843676; -.
DR Gramene; AT1G73410.1; AT1G73410.1; AT1G73410.
DR KEGG; ath:AT1G73410; -.
DR Araport; AT1G73410; -.
DR TAIR; locus:2206910; AT1G73410.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_18_1_1; -.
DR InParanoid; Q9FX36; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9FX36; -.
DR PRO; PR:Q9FX36; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FX36; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; ISS:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:2000652; P:regulation of secondary cell wall biogenesis; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Cell wall biogenesis/degradation; DNA-binding; Nucleus; Reference proteome;
KW Repeat; Transcription; Transcription regulation.
FT CHAIN 1..243
FT /note="Transcription factor MYB54"
FT /id="PRO_0000442991"
FT DOMAIN 1..52
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 53..107
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 29..51
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 80..103
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 206..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 176
FT /note="T -> P (in Ref. 1; AAC83612)"
FT /evidence="ECO:0000305"
FT CONFLICT 182
FT /note="N -> S (in Ref. 1; AAC83612)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 243 AA; 28205 MW; 8B0728A939E764F5 CRC64;
MIMCSRGHWR PAEDEKLKDL VEQYGPHNWN AIALKLPGRS GKSCRLRWFN QLDPRINRNP
FTEEEEERLL AAHRIHGNRW SIIARLFPGR TDNAVKNHWH VIMARRTRQT SKPRLLPSTT
SSSSLMASEQ IMMSSGGYNH NYSSDDRKKI FPADFINFPY KFSHINHLHF LKEFFTGKIA
LNHKANQSKK PMEFYNFLQV NTDSNKSEII DQDSGQSKRS DSDTKHESHV PFFDFLSVGN
SAS
