MYB82_ARATH
ID MYB82_ARATH Reviewed; 201 AA.
AC Q9LTF7; O49804; Q9SQJ6; Q9ZTC4;
DT 16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Transcription factor MYB82;
DE AltName: Full=Myb-related protein 82;
DE Short=AtMYB82;
GN Name=MYB82; OrderedLocusNames=At5g52600; ORFNames=F6N7.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Li S.F., Heazlewood J., Parish R.W.;
RT "Cloning of three MYB-like genes from Arabidopsis thaliana.";
RL (er) Plant Gene Register PGR99-138(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L.-J., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 55-99.
RC STRAIN=cv. Landsberg erecta;
RA Romero I., Fuertes A., Benito M.J., Malpica J., Leyva A., Paz-Ares J.;
RT "One hundred R2R3-MYB genes in the genome of Arabidopsis thaliana.";
RL Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 85-201, AND INDUCTION.
RC STRAIN=cv. Columbia;
RX PubMed=9839469; DOI=10.1046/j.1365-313x.1998.00278.x;
RA Kranz H.D., Denekamp M., Greco R., Jin H.-L., Leyva A., Meissner R.C.,
RA Petroni K., Urzainqui A., Bevan M., Martin C., Smeekens S., Tonelli C.,
RA Paz-Ares J., Weisshaar B.;
RT "Towards functional characterisation of the members of the R2R3-MYB gene
RT family from Arabidopsis thaliana.";
RL Plant J. 16:263-276(1998).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [8]
RP INTERACTION WITH BHLH012 AND BHLH042.
RX PubMed=15361138; DOI=10.1111/j.1365-313x.2004.02183.x;
RA Zimmermann I.M., Heim M.A., Weisshaar B., Uhrig J.F.;
RT "Comprehensive identification of Arabidopsis thaliana MYB transcription
RT factors interacting with R/B-like BHLH proteins.";
RL Plant J. 40:22-34(2004).
RN [9]
RP GENE FAMILY.
RX PubMed=16463103; DOI=10.1007/s11103-005-2910-y;
RA Chen Y., Yang X., He K., Liu M., Li J., Gao Z., Lin Z., Zhang Y., Wang X.,
RA Qiu X., Shen Y., Zhang L., Deng X., Luo J., Deng X.-W., Chen Z., Gu H.,
RA Qu L.-J.;
RT "The MYB transcription factor superfamily of Arabidopsis: expression
RT analysis and phylogenetic comparison with the rice MYB family.";
RL Plant Mol. Biol. 60:107-124(2006).
RN [10]
RP FUNCTION, SUBCELLULAR LOCATION, DOMAIN, TISSUE SPECIFICITY, INTERACTION
RP WITH GL1 AND GL3, AND SUBUNIT.
RC STRAIN=cv. Columbia;
RX PubMed=24803498; DOI=10.1093/jxb/eru179;
RA Liang G., He H., Li Y., Ai Q., Yu D.;
RT "MYB82 functions in regulation of trichome development in Arabidopsis.";
RL J. Exp. Bot. 65:3215-3223(2014).
CC -!- FUNCTION: Transcription activation factor positively regulating
CC trichomes development (PubMed:24803498). Has a function nearly
CC equivalent to that of GL1 and can complement gl1 mutants
CC (PubMed:24803498). {ECO:0000269|PubMed:24803498}.
CC -!- SUBUNIT: Homodimer and heterodimer with GL1 (PubMed:24803498). Part of
CC the WD40-bHLH-MYB complex (PubMed:24803498). Interacts with
CC BHLH012/MYC1 and BHLH042/TT8 (PubMed:15361138). Interacts (via N-
CC terminus) with GL1 and GL3 (PubMed:24803498).
CC {ECO:0000269|PubMed:15361138, ECO:0000269|PubMed:24803498}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:24803498}.
CC -!- TISSUE SPECIFICITY: Mainly expressed in the trichomes of new leaves.
CC {ECO:0000269|PubMed:24803498}.
CC -!- INDUCTION: By auxin (IAA). {ECO:0000269|PubMed:9839469}.
CC -!- DOMAIN: The N-terminal domain is necessary and sufficient for dimer
CC formation. The C-terminal domain is responsible for the transcription
CC activation function. {ECO:0000269|PubMed:24803498}.
CC -!- MISCELLANEOUS: At least one of the two introns in the MYB82 gene is
CC essential to the protein's trichome developmental function. The MYB-
CC binding box (5'-TAAGCCAGTTATGTCT-3') located in the third exon of the
CC MYB82 gene is required for MYB82 function in trichome initiation.
CC {ECO:0000269|PubMed:24803498}.
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DR EMBL; AF048841; AAF14064.1; -; Genomic_DNA.
DR EMBL; AY519637; AAS10107.1; -; mRNA.
DR EMBL; AB025606; BAA98078.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96239.1; -; Genomic_DNA.
DR EMBL; Z95805; CAB09237.1; -; mRNA.
DR EMBL; AF062912; AAC83634.2; -; mRNA.
DR PIR; T51684; T51684.
DR RefSeq; NP_680426.1; NM_148121.3.
DR AlphaFoldDB; Q9LTF7; -.
DR SMR; Q9LTF7; -.
DR BioGRID; 20582; 6.
DR IntAct; Q9LTF7; 3.
DR STRING; 3702.AT5G52600.1; -.
DR PaxDb; Q9LTF7; -.
DR PRIDE; Q9LTF7; -.
DR EnsemblPlants; AT5G52600.1; AT5G52600.1; AT5G52600.
DR GeneID; 835337; -.
DR Gramene; AT5G52600.1; AT5G52600.1; AT5G52600.
DR KEGG; ath:AT5G52600; -.
DR Araport; AT5G52600; -.
DR TAIR; locus:504955052; AT5G52600.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_25_4_1; -.
DR InParanoid; Q9LTF7; -.
DR OMA; ESNTWME; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9LTF7; -.
DR PRO; PR:Q9LTF7; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9LTF7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0010026; P:trichome differentiation; IMP:TAIR.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..201
FT /note="Transcription factor MYB82"
FT /id="PRO_0000358834"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 112..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 120
FT /note="R -> K (in Ref. 1; AAF14064)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 201 AA; 23292 MW; 1DDFADFF09FCFFC7 CRC64;
MECKREEGKS YVKRGLWKPE EDMILKSYVE THGEGNWADI SRRSGLKRGG KSCRLRWKNY
LRPNIKRGSM SPQEQDLIIR MHKLLGNRWS LIAGRLPGRT DNEVKNYWNT HLNKKPNSRR
QNAPESIVGA TPFTDKPVMS TELRRSHGEG GEEESNTWME ETNHFGYDVH VGSPLPLISH
YPDNTLVFDP CFSFTDFFPL L
