MYB83_ARATH
ID MYB83_ARATH Reviewed; 343 AA.
AC Q9C6U1; A0MEU8; O49805; Q67ZR9; Q6QAE3;
DT 05-JUL-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 166.
DE RecName: Full=Transcription factor MYB83 {ECO:0000303|PubMed:11597504};
DE AltName: Full=Myb-related protein 83 {ECO:0000303|PubMed:11597504};
DE Short=AtMYB83 {ECO:0000303|PubMed:11597504};
GN Name=MYB83 {ECO:0000303|PubMed:11597504};
GN OrderedLocusNames=At3g08500 {ECO:0000312|Araport:AT3G08500};
GN ORFNames=T8G24.3 {ECO:0000312|EMBL:AAG50833.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L.-J., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: a genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF Clones.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [9]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 73-117.
RC STRAIN=cv. Landsberg erecta;
RA Romero I., Fuertes A., Benito M.J., Malpica J., Leyva A., Paz-Ares J.;
RT "One hundred R2R3-MYB genes in the genome of Arabidopsis thaliana.";
RL Submitted (MAY-1997) to the EMBL/GenBank/DDBJ databases.
RN [10]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=19808805; DOI=10.1093/pcp/pcp139;
RA McCarthy R.L., Zhong R., Ye Z.-H.;
RT "MYB83 is a direct target of SND1 and acts redundantly with MYB46 in the
RT regulation of secondary cell wall biosynthesis in Arabidopsis.";
RL Plant Cell Physiol. 50:1950-1964(2009).
RN [11]
RP FUNCTION.
RX PubMed=22197883; DOI=10.1093/pcp/pcr185;
RA Zhong R., Ye Z.H.;
RT "MYB46 and MYB83 bind to the SMRE sites and directly activate a suite of
RT transcription factors and secondary wall biosynthetic genes.";
RL Plant Cell Physiol. 53:368-380(2012).
CC -!- FUNCTION: Transcription factor that acts as molecular switch in the
CC NAC012/SND1-mediated transcriptional network regulating secondary wall
CC biosynthesis. Is directly activated by NAC012/SND1 and its close
CC homologs, including NAC043/NST1, NAC066/NST2, NAC101/VND6 and
CC NAC030/VND7. Is required for functional expression of a number of
CC secondary wall-associated transcription factors and secondary wall
CC biosynthetic genes involved in cellulose, xylan and lignin synthesis.
CC Functions redundantly with MYB46 in the transcriptional regulatory
CC cascade leading to secondary wall formation in fibers and vessels
CC (PubMed:19808805). Transcription activator that binds to the DNA
CC consensus sequence 5'-ACC[AT]A[AC][TC]-3', designated as the secondary
CC wall MYB-responsive element (SMRE). Regulates directly numerous
CC transcription factors and a number of genes involved in secondary wall
CC biosynthesis that contain SMRE elements in their promoters
CC (PubMed:22197883). {ECO:0000269|PubMed:19808805,
CC ECO:0000269|PubMed:22197883}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000269|PubMed:19808805}.
CC -!- TISSUE SPECIFICITY: Expressed specifically in fiber and vessel cells
CC that are undergoing secondary wall thickening in floral stems.
CC Expressed in vessels but not in xylary fibers in the developing
CC secondary xylem of roots. {ECO:0000269|PubMed:19808805}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions, but the double mutant plants myb48 and myb83 nearly lack
CC secondary wall thickening, stop growing after developing one to two
CC pairs of small leaves and subsequently die.
CC {ECO:0000269|PubMed:19808805}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28548.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF371974; AAK54738.1; -; mRNA.
DR EMBL; AY550293; AAS58504.1; -; mRNA.
DR EMBL; AC074395; AAG50833.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74637.1; -; Genomic_DNA.
DR EMBL; DQ446645; ABE65926.1; -; mRNA.
DR EMBL; DQ653071; ABK28548.1; ALT_SEQ; mRNA.
DR EMBL; AK176048; BAD43811.1; -; mRNA.
DR EMBL; BT026506; ABH04613.1; -; mRNA.
DR EMBL; AB493606; BAH30444.1; -; mRNA.
DR EMBL; Z95806; CAB09238.1; -; mRNA.
DR RefSeq; NP_187463.1; NM_111685.3.
DR AlphaFoldDB; Q9C6U1; -.
DR SMR; Q9C6U1; -.
DR STRING; 3702.AT3G08500.1; -.
DR PaxDb; Q9C6U1; -.
DR PRIDE; Q9C6U1; -.
DR EnsemblPlants; AT3G08500.1; AT3G08500.1; AT3G08500.
DR GeneID; 819997; -.
DR Gramene; AT3G08500.1; AT3G08500.1; AT3G08500.
DR KEGG; ath:AT3G08500; -.
DR Araport; AT3G08500; -.
DR TAIR; locus:2103459; AT3G08500.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_16_2_1; -.
DR InParanoid; Q9C6U1; -.
DR OMA; VTGNQFD; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9C6U1; -.
DR PRO; PR:Q9C6U1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9C6U1; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:2000652; P:regulation of secondary cell wall biogenesis; IMP:TAIR.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..343
FT /note="Transcription factor MYB83"
FT /id="PRO_0000440860"
FT DOMAIN 27..79
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 80..134
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 55..79
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 107..130
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 64
FT /note="L -> P (in Ref. 2; AAS58504)"
FT /evidence="ECO:0000305"
FT CONFLICT 246
FT /note="I -> V (in Ref. 6; BAD43811)"
FT /evidence="ECO:0000305"
FT CONFLICT 296
FT /note="H -> Y (in Ref. 5; ABK28548)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 343 AA; 38419 MW; A06928F5F3C4610A CRC64;
MMMRKPDITT IRDKGKPNHA CGGNNNKPKL RKGLWSPDED EKLIRYMLTN GQGCWSDIAR
NAGLLRCGKS CRLRWINYLR PDLKRGSFSP QEEDLIFHLH SILGNRWSQI ATRLPGRTDN
EIKNFWNSTL KKRLKNNSNN NTSSGSSPNN SNSNSLDPRD QHVDMGGNST SLMDDYHHDE
NMMTVGNTMR MDSSSPFNVG PMVNSVGLNQ LYDPLMISVP DNGYHQMGNT VNVFSVNGLG
DYGNTILDPI SKRVSVEGDD WFIPPSENTN VIACSTSNNL NLQALDPCFN SKNLCHSESF
KVGNVLGIEN GSWEIENPKI GDWDLDGLID NNSSFPFLDF QVD
