MYB8_ARATH
ID MYB8_ARATH Reviewed; 212 AA.
AC Q9SDS8; Q9LQE2;
DT 18-JAN-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 161.
DE RecName: Full=Transcription factor MYB8 {ECO:0000305};
DE AltName: Full=Myb-related protein 8 {ECO:0000303|PubMed:16463103};
DE Short=AtMYB8 {ECO:0000303|PubMed:16463103};
GN Name=MYB8 {ECO:0000303|PubMed:16463103};
GN OrderedLocusNames=At1g35515 {ECO:0000312|Araport:AT1G35515};
GN ORFNames=F15O4.43 {ECO:0000312|EMBL:AAF79367.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11597504; DOI=10.1016/s1369-5266(00)00199-0;
RA Stracke R., Werber M., Weisshaar B.;
RT "The R2R3-MYB gene family in Arabidopsis thaliana.";
RL Curr. Opin. Plant Biol. 4:447-456(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16463103; DOI=10.1007/s11103-005-2910-y;
RA Chen Y., Yang X., He K., Liu M., Li J., Gao Z., Lin Z., Zhang Y., Wang X.,
RA Qiu X., Shen Y., Zhang L., Deng X., Luo J., Deng X.-W., Chen Z., Gu H.,
RA Qu L.-J.;
RT "The MYB transcription factor superfamily of Arabidopsis: expression
RT analysis and phylogenetic comparison with the rice MYB family.";
RL Plant Mol. Biol. 60:107-124(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP CAUTION.
RX PubMed=15994234; DOI=10.1073/pnas.0503960102;
RA Zhu J., Verslues P.E., Zheng X., Lee B.H., Zhan X., Manabe Y.,
RA Sokolchik I., Zhu Y., Dong C.H., Zhu J.K., Hasegawa P.M., Bressan R.A.;
RT "HOS10 encodes an R2R3-type MYB transcription factor essential for cold
RT acclimation in plants.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:9966-9971(2005).
RN [6]
RP RETRACTION NOTICE OF PUBMED:15994234.
RX PubMed=20622156; DOI=10.1073/pnas.1009100107;
RA Zhu J., Verslues P.E., Zheng X., Lee B.H., Zhan X., Manabe Y.,
RA Sokolchik I., Zhu Y., Dong C.H., Zhu J.K., Hasegawa P.M., Bressan R.A.;
RT "Retraction for Zhu et al., HOS10 encodes an R2R3-type MYB transcription
RT factor essential for cold acclimation in plants.";
RL Proc. Natl. Acad. Sci. U.S.A. 107:13972-13972(2010).
CC -!- FUNCTION: Transcription activator. {ECO:0000250|UniProtKB:Q38850}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- CAUTION: This protein has been described as HOS10 (high expression of
CC osmotically responsive genes 10), a coordinating factor for responses
CC to abiotic stress and for growth and development (PubMed:15994234).
CC However, due to a locus misidentification, the locus responsible for
CC the HOS10 phenotypes reported in ecotype C24 remains unknown and the
CC paper has been retracted (PubMed:20622156). {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF79367.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF207991; AAF20989.1; -; mRNA.
DR EMBL; AY519561; AAS10031.1; -; mRNA.
DR EMBL; AC007887; AAF79367.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE31803.1; -; Genomic_DNA.
DR PIR; D86476; D86476.
DR RefSeq; NP_849749.1; NM_179418.2.
DR AlphaFoldDB; Q9SDS8; -.
DR SMR; Q9SDS8; -.
DR IntAct; Q9SDS8; 7.
DR STRING; 3702.AT1G35515.1; -.
DR PaxDb; Q9SDS8; -.
DR PRIDE; Q9SDS8; -.
DR EnsemblPlants; AT1G35515.1; AT1G35515.1; AT1G35515.
DR GeneID; 840446; -.
DR Gramene; AT1G35515.1; AT1G35515.1; AT1G35515.
DR KEGG; ath:AT1G35515; -.
DR Araport; AT1G35515; -.
DR TAIR; locus:1005716764; AT1G35515.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_23_3_1; -.
DR InParanoid; Q9SDS8; -.
DR OMA; METSCEN; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9SDS8; -.
DR PRO; PR:Q9SDS8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SDS8; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..212
FT /note="Transcription factor MYB8"
FT /id="PRO_0000438735"
FT DOMAIN 9..61
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 62..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
SQ SEQUENCE 212 AA; 24239 MW; 6F3E4C387B8F017D CRC64;
MGRSPCCEKA HMNKGAWTKE EDQRLIDYIR NHGEGSWRSL PKSVGLLRCG KSCRLRWINY
LRPDLKRGNF TDGEEQIIVK LHSLFGNKWS LIAGKLPGRT DNEIKNYWNT HIKRKLLNRG
IDPKTHGSII EPKTTSFHPR NEDLKSTFPG SVKLKMETSC ENCASTSGTT TDEDLRLSVD
CDYRYDHLDK ELNLDLTLGY SPTRFVGVGS CY
