MYB94_ARATH
ID MYB94_ARATH Reviewed; 333 AA.
AC Q9SN78; Q9ZTC1;
DT 31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 173.
DE RecName: Full=Transcription factor MYB94 {ECO:0000303|PubMed:9839469};
DE AltName: Full=Myb-related protein 94 {ECO:0000303|PubMed:9839469};
DE Short=AtMYB94 {ECO:0000303|PubMed:9839469};
GN Name=MYB94 {ECO:0000303|PubMed:9839469}; Synonyms=ATMYBCP70;
GN OrderedLocusNames=At3g47600 {ECO:0000312|Araport:AT3G47600};
GN ORFNames=F1P2.150 {ECO:0000312|EMBL:CAB61986.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=9839469; DOI=10.1046/j.1365-313x.1998.00278.x;
RA Kranz H.D., Denekamp M., Greco R., Jin H.-L., Leyva A., Meissner R.C.,
RA Petroni K., Urzainqui A., Bevan M., Martin C., Smeekens S., Tonelli C.,
RA Paz-Ares J., Weisshaar B.;
RT "Towards functional characterisation of the members of the R2R3-MYB gene
RT family from Arabidopsis thaliana.";
RL Plant J. 16:263-276(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Qu L., Gu H.;
RT "The MYB transcription factor family in Arabidopsis: A genome-wide cloning
RT and expression pattern analysis.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=25305760; DOI=10.1093/pcp/pcu142;
RA Lee S.B., Suh M.C.;
RT "Cuticular wax biosynthesis is up-regulated by the MYB94 transcription
RT factor in Arabidopsis.";
RL Plant Cell Physiol. 56:48-60(2015).
RN [7]
RP FUNCTION.
RX PubMed=27577115; DOI=10.1093/pcp/pcw147;
RA Lee S.B., Kim H.U., Suh M.C.;
RT "MYB94 and MYB96 additively activate cuticular wax biosynthesis in
RT Arabidopsis.";
RL Plant Cell Physiol. 57:2300-2311(2016).
CC -!- FUNCTION: Transcription activator involved in the activation of
CC cuticular wax biosynthesis under drought stress. Binds directly to the
CC promoters of genes involved in cuticular wax biosynthesis.
CC Transactivates WSD1, KCS2/DAISY, CER1, CER2, FAR3 and ECR genes
CC (PubMed:25305760, PubMed:27577115). Functions together with MYB96 in
CC the activation of cuticular wax biosynthesis (PubMed:27577115).
CC {ECO:0000269|PubMed:25305760, ECO:0000269|PubMed:27577115}.
CC -!- INTERACTION:
CC Q9SN78; Q9LXY8: T5P19_170; NbExp=3; IntAct=EBI-4429731, EBI-15200578;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625,
CC ECO:0000269|PubMed:25305760}.
CC -!- TISSUE SPECIFICITY: Expressed in germinating seeds, rosette and cauline
CC leaves, flower buds, open flowers, stems and developing siliques.
CC {ECO:0000269|PubMed:25305760}.
CC -!- INDUCTION: Induced by salt stress, osmotic shock and abscisic acid
CC (ABA). {ECO:0000269|PubMed:25305760}.
CC -!- MISCELLANEOUS: Plants overexpressing MYB94 exhibit deposition of
CC epicuticuar wax crystals on leaf surface.
CC {ECO:0000269|PubMed:25305760}.
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DR EMBL; AF062918; AAC83640.1; -; mRNA.
DR EMBL; AY519595; AAS10065.1; -; mRNA.
DR EMBL; AL132955; CAB61986.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78306.1; -; Genomic_DNA.
DR EMBL; BT002802; AAO22626.1; -; mRNA.
DR EMBL; BT004361; AAO42355.1; -; mRNA.
DR PIR; T45720; T45720.
DR RefSeq; NP_190344.1; NM_114628.4.
DR AlphaFoldDB; Q9SN78; -.
DR SMR; Q9SN78; -.
DR IntAct; Q9SN78; 4.
DR STRING; 3702.AT3G47600.1; -.
DR PaxDb; Q9SN78; -.
DR PRIDE; Q9SN78; -.
DR ProteomicsDB; 251374; -.
DR EnsemblPlants; AT3G47600.1; AT3G47600.1; AT3G47600.
DR GeneID; 823914; -.
DR Gramene; AT3G47600.1; AT3G47600.1; AT3G47600.
DR KEGG; ath:AT3G47600; -.
DR Araport; AT3G47600; -.
DR TAIR; locus:2079182; AT3G47600.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_028567_6_0_1; -.
DR InParanoid; Q9SN78; -.
DR OMA; MADECNA; -.
DR OrthoDB; 1499244at2759; -.
DR PhylomeDB; Q9SN78; -.
DR PRO; PR:Q9SN78; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SN78; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:UniProtKB.
DR GO; GO:1904278; P:positive regulation of wax biosynthetic process; IMP:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR GO; GO:0009733; P:response to auxin; IBA:GO_Central.
DR GO; GO:0009414; P:response to water deprivation; IMP:UniProtKB.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 1: Evidence at protein level;
KW Activator; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Stress response; Transcription; Transcription regulation.
FT CHAIN 1..333
FT /note="Transcription factor MYB94"
FT /id="PRO_0000442918"
FT DOMAIN 9..65
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 66..116
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 37..61
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 89..112
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 134..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 201
FT /note="S -> STT (in Ref. 1; AAC83640)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 333 AA; 37144 MW; FD31160F0F0D3B92 CRC64;
MGRPPCCDKI GVKKGPWTPE EDIILVSYIQ EHGPGNWRSV PTHTGLRRCS KSCRLRWTNY
LRPGIKRGNF TEHEEKMILH LQALLGNRWA AIASYLPERT DNDIKNYWNT HLKKKLKKMN
DSCDSTINNG LDNKDFSISN KNTTSHQSSN SSKGQWERRL QTDINMAKQA LCDALSIDKP
QNPTNFSIPD LGYGPSSSSS STTTTTTTTR NTNPYPSGVY ASSAENIARL LQNFMKDTPK
TSVPLPVAAT EMAITTAASS PSTTEGDGEG IDHSLFSFNS IDEAEEKPKL IDHDINGLIT
QGSLSLFEKW LFDEQSHDMI INNMSLEGQE VLF
