MYBAA_DICDI
ID MYBAA_DICDI Reviewed; 971 AA.
AC B0G0Y5;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Myb-like protein AA;
GN Name=mybAA; ORFNames=DDB_G0268368;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
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DR EMBL; AAFI02000003; EDR41123.1; -; Genomic_DNA.
DR RefSeq; XP_001732948.1; XM_001732896.1.
DR AlphaFoldDB; B0G0Y5; -.
DR SMR; B0G0Y5; -.
DR STRING; 44689.DDB0238728; -.
DR PaxDb; B0G0Y5; -.
DR EnsemblProtists; EDR41123; EDR41123; DDB_G0268368.
DR GeneID; 8616180; -.
DR KEGG; ddi:DDB_G0268368; -.
DR dictyBase; DDB_G0268368; mybAA.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_305541_0_0_1; -.
DR InParanoid; B0G0Y5; -.
DR OMA; NYCAINT; -.
DR PRO; PR:B0G0Y5; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..971
FT /note="Myb-like protein AA"
FT /id="PRO_0000329399"
FT DOMAIN 752..803
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 804..858
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 780..802
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 831..854
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 440..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 874..898
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 911..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..681
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..716
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 748..765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 110871 MW; 092A89BE814905A3 CRC64;
MELTTEAPFI NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN TPNNTSYSNY PQSGYVYQNY
PLNNNNGGNN NNTIYYNQPQ QYDPNYQTSV TSNSYPQYSY FASPNIISPI PSPCLGSTPS
PIPSPTIYQY SNNSNNYCAI NTPPLTSVPS PILNCNNKKR PEFNNNNNNH NHNNNNNNNN
NNNNYNYNNS NNNQQQQKQQ QQQQQQQQQP QQPQQQSQQQ QQQQQQQQQQ QQQQFKQTNI
NTTPKNLSPV LQSVNSSASS TPQIQSYFQQ PQYQQQYQQQ YQQQYQQYQQ PQQLSSANTT
PQTNERPNYS SIIQPNQLFS QMVPSFINGA INNNNNNNNN NNNNNNNNNN NNNNNNNNNN
NNNNTTTNNN NNNNNNNNYN NITYFQPYTP FSIVDNSSMI VPDKQPQQQQ PQQQPQQQQQ
QQQQQQQQQQ QQQQQQQQQQ QQQQQQQNYN DDSNKNNNNN NNNNNNNNNN NNNNNNNNNE
NINSSNNNNM YNICPAAAYQ NIQFIKEQSN SSLSSSQPIP PFNLYNEQPQ QQPQQPQPTQ
SQPILSSSST SVFDINHHHH HQQQQQQQQQ QQQQQQQQQQ QQQQQQQQQQ PQPNLSSSSY
ADNNNSFQSS SGNVWESQSS PIQSSVQISS PPQSNQSSIA PAPAVNLSAS ASSVATTTKQ
SNVKKQKQQQ QQQQQQQQTK RQELSDSEDD TDNGDDIDED DEDDDEDEDD MEDEDTSSSS
SSSSSSSSLS KKSPAVKKSG LKKSGRSKSS SNESKAKGHW TKEEDEKLRS LVDLHGTKRW
KYIASLLCLR NGRQCRERWS NQLDPSIKRD AWTLEEDRII LDAHSKYGNK WAEISKLLPG
RTNCAIKNHW NSTMKRKLSK KQYDFSSLPP ISSSIVSDNS SSLSTPTDSI SSSPSTSPIT
LSSNVVVNDF DSQQQQQQQQ TYQQPPPQSQ DSGNNQFNFN NNNNNNNNNN NNNNNSVESI
KLYTNVNISY I
