ID   MYBB_XENLA              Reviewed;         743 AA.
AC   P52551;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Myb-related protein B;
DE            Short=B-Myb;
DE   AltName: Full=Myb-like protein 2;
DE   AltName: Full=Myb-related protein 1;
DE   AltName: Full=XMYB1;
GN   Name=mybl2; Synonyms=bmyb, myb1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1606020; DOI=10.1016/0925-4773(92)90015-c;
RA   Bouwmeester T., Guehmann S., El-Baradi T., Kalkbrenner F., van Wijk I.,
RA   Moelling K., Pieler T.;
RT   "Molecular cloning, expression and in vitro functional characterization of
RT   Myb-related proteins in Xenopus.";
RL   Mech. Dev. 37:57-68(1992).
RN   [2]
RP   SEQUENCE REVISION TO C-TERMINUS.
RX   PubMed=10187816; DOI=10.1074/jbc.274.15.10293;
RA   Humbert-Lan G., Pieler T.;
RT   "Regulation of DNA binding activity and nuclear transport of B-Myb in
RT   Xenopus oocytes.";
RL   J. Biol. Chem. 274:10293-10300(1999).
CC   -!- SUBUNIT: Component of the DREAM complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus.
CC   -!- DEVELOPMENTAL STAGE: Present throughout oogenesis and early Xenopus
CC       embryogenesis; in adult tissue it is primarily detected in blood.
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DR   EMBL; M75870; AAC98701.1; -; mRNA.
DR   AlphaFoldDB; P52551; -.
DR   SMR; P52551; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00167; SANT; 3.
DR   InterPro; IPR015395; C-myb_C.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017930; Myb_dom.
DR   InterPro; IPR001005; SANT/Myb.
DR   Pfam; PF09316; Cmyb_C; 1.
DR   Pfam; PF00249; Myb_DNA-binding; 1.
DR   SMART; SM00717; SANT; 3.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   PROSITE; PS51294; HTH_MYB; 3.
PE   2: Evidence at transcript level;
KW   DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..743
FT                   /note="Myb-related protein B"
FT                   /id="PRO_0000197061"
FT   DOMAIN          26..77
FT                   /note="HTH myb-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DOMAIN          78..133
FT                   /note="HTH myb-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DOMAIN          134..184
FT                   /note="HTH myb-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DNA_BIND        54..77
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DNA_BIND        106..129
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   DNA_BIND        157..180
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          221..262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          381..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        236..262
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   743 AA;  82910 MW;  5FD1D678BB24409B CRC64;
     MSRRSRGDDL EDLQYQDTDS DVPEPKENRV KVKWTPEEDE TLKALVKKHG QGEWKTIASN
     LNNRTEQQCQ HRWLRVLHPD LVKGPWTKEE DEKVIELVKK YGTKHWTLIA KQLRGRMGKQ
     CRERWHNHLN PEVKKSSWTE EEDRIICQAH KVLGNRWAEI AKLLPGRTDN AVKNHWNSTI
     KRKVETGGFL TVKASGQQEE REDSGYQAAE DQNHVLLSEP VERSANIPEE PSNILSPKLL
     TKSPGIRSEQ ESGGEGSNSE SATAIVDSAP EKWMVEYVNF LVPGSDIMES DPEAWCELSS
     FDLGEDSTVS DVGSPTHAAV TDKPQASNVT EYRLDGHTLS DLCKGNKGEL IPISPQPQTA
     FGTPPSVLKQ HKKRKITLSP VTENGGSITT SVTEANSMTP KSTPVKSLPF SPSQFLNFWS
     KQDALELENP SLTSTPVCSQ KTMVTTPLHR DKTPLLQKNS VFITPNNKFA ADHVLHTPTP
     FKNALEKFGS LKPLPPTPHL EEDLKEVLRS ESGIELIIVD EPKLERQKRK PHSPMKKVRK
     SLALDIIDKH PKPSSLTLPS AVSAHMQPQT CDSFLSVSLN ESSCSREENS VLNQGFVQVK
     TSKGAVVQLG NTSQLLTDIG ELVKTQCSLR NTETATPFKT ENGTFTNTDL CPQSLMDLDT
     FHSTAVASNK CPTIKTETLF QVKPEKTKMQ RHNIMNIPEP MTAAWKTVAF GGSQDQMLMQ
     EKARAILNLT YKHSSTSRAL VLS