MYBK_DICDI
ID MYBK_DICDI Reviewed; 894 AA.
AC Q86HX9; Q550F9;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Myb-like protein K;
GN Name=mybK; ORFNames=DDB_G0276877;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
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DR EMBL; AAFI02000019; EAL68940.1; -; Genomic_DNA.
DR RefSeq; XP_642973.1; XM_637881.1.
DR AlphaFoldDB; Q86HX9; -.
DR SMR; Q86HX9; -.
DR STRING; 44689.DDB0220507; -.
DR PaxDb; Q86HX9; -.
DR EnsemblProtists; EAL68940; EAL68940; DDB_G0276877.
DR GeneID; 8620845; -.
DR KEGG; ddi:DDB_G0276877; -.
DR dictyBase; DDB_G0276877; mybK.
DR eggNOG; ENOG502RDH7; Eukaryota.
DR HOGENOM; CLU_323509_0_0_1; -.
DR InParanoid; Q86HX9; -.
DR OMA; LENNAHY; -.
DR PRO; PR:Q86HX9; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00167; SANT; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR017884; SANT_dom.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..894
FT /note="Myb-like protein K"
FT /id="PRO_0000329386"
FT DOMAIN 649..704
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 677..700
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 93..221
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 299..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 492..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 601..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 610..659
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..739
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 740..755
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 756..802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 817..852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 894 AA; 100912 MW; 96144BA87696D906 CRC64;
MQSDTLTVQT VPNTTNVTNT EHSMLAKIEE NRHIIQTIWE KQNLGKLTEC EQFQKRLHSN
LLLLAPLADH QQNYHKQQQA LLQQQQQQQQ ALLQQQQQSP VTNVATNTPP TLQHSISSPS
PNNFNNNNNA NNQFLSPNSP QVAKSSPSQN NPSTPIANTP TTTTTTAATT ATNTNTMMSG
SSGGVVSPVS NQQQQQSIQS PSQQSVVQRS PSQSLNSSAS SIQSLQNIQN TQNTIQQLTN
SLTQVKTIIQ QYQSQNQQVP QDVISRYHEF YSMLQQQQQN LLQQQSLLQQ QQALLQQQQV
GNPMQQSNDM QPQTPQQNNM QQQQQPQTPQ QTNMQQPQTP QQNSMQPSQQ PITQQEYQQI
YDKIVSMSSQ ILLCNQNIQK LQSESYDPHV LQGLQNQVAN LEIAQANSLR FLPQQYHVVL
FQQQQQQQAN QQQLQLMQIK QSKEYMVLTP AQQLIYNQQI QQNHYNQQVI LRQQQQKLMA
ILEQQNQMIA QQQQQQHQMH QQHQMQPQQQ QQQHQMHQQS PQQPQQMGMG GNPPSLEMIS
PMSAVMNGVT SPMNQGMMSS NNGMPTITTS LSAISPTSPI GTNLNMSNPT TTTVANVTTT
AATTTTASSS GKEEKEKKKD KKDKDKDKDK DDDDKESKKD KKDKKDKKAS KEKTSHWTSE
EHNKFLEAVQ QFGIKDYHAI AKFVQTRNHH QVRTHVNTYL KNQKKAEAAT SSTQVSTPQQ
QLPIVGTPQQ SVGTPQQQQP PIEQTPPPPQ QQQQPPQLTP EQQLASQQQQ ATLQFQQYQQ
PQDQQQQQYQ QYQQYDPQQQ QQQPQQQPPP PQTTPPNNEN NNNINNNLEN TNNNDNGNNN
NNEYNSGFDS NSGLNDEMGI GLFGSPGNNS NNNLGISIEG NNFDDNPSIS SPGV
