MYBL_DICDI
ID MYBL_DICDI Reviewed; 855 AA.
AC Q54NA6;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Myb-like protein L;
GN Name=mybL; ORFNames=DDB_G0285373;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
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DR EMBL; AAFI02000079; EAL64761.1; -; Genomic_DNA.
DR RefSeq; XP_638274.1; XM_633182.1.
DR AlphaFoldDB; Q54NA6; -.
DR SMR; Q54NA6; -.
DR STRING; 44689.DDB0220511; -.
DR PaxDb; Q54NA6; -.
DR EnsemblProtists; EAL64761; EAL64761; DDB_G0285373.
DR GeneID; 8625082; -.
DR KEGG; ddi:DDB_G0285373; -.
DR dictyBase; DDB_G0285373; mybL.
DR eggNOG; KOG0049; Eukaryota.
DR HOGENOM; CLU_334176_0_0_1; -.
DR InParanoid; Q54NA6; -.
DR OMA; ERYCNVL; -.
DR PRO; PR:Q54NA6; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00167; SANT; 3.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 5.
DR SUPFAM; SSF46689; SSF46689; 4.
DR PROSITE; PS51294; HTH_MYB; 3.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 3: Inferred from homology;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation.
FT CHAIN 1..855
FT /note="Myb-like protein L"
FT /id="PRO_0000329387"
FT DOMAIN 539..595
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 596..646
FT /note="Myb-like"
FT DOMAIN 647..702
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 703..754
FT /note="HTH myb-type 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 567..591
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 675..698
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 727..750
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 26..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 169..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 480..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 800..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 291..324
FT /evidence="ECO:0000255"
FT COMPBIAS 175..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..828
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 855 AA; 97860 MW; 7F5AC498220030BD CRC64;
MSNANGNSNG KQNNDLEDLQ SLNLLLSNSN NNNNNNNNNN NNNNNNNNNN NNNNNKNNNN
NNSNISSNGN INYTESQTFK EHPIGLPKPV QEFVTKLMTH RNNLIETNAI DKPFLIPPSK
EVVDLFKTYK KSMNDANGIQ DEDQDDTDDE FALLPDDHYD EELILDEDYQ DGNDENDTNN
SNNANTTTRN NTTTAIQNNA LTIPNSSSSS SYNLIEAIGN LNNNNTLGTT TTTTTTTTTT
TSLPDLNLNF DSSELFKKFK NDNHQNHDSN INNNNKILND GLDVTNLLKI NKEYQEFIKK
YLQKIEEEQK RNKEMLAQAR KSIHVTIGPR TIKGGGFRKK GIAKEQLDNS DSDNGGGGNG
GGFDDEYVNC SCIGTCICID SNGQPLFKRK KPGIPYFSFE VEVDGVIQTH YPADNPDSEN
IRITKNNMPL YFKTRRWTKK ESELLLKGIK EKNLQKKLYR LSEDKLSKAE YEKKLKQIQR
SSNNNNNNNN NINNNNNNNS IKDKQDFVAP TMQVISQVCV ESLTRSPLEA YLRWKNHDDP
SINKGPFTKE EDKKLLTLAK KYDGHEWEKI SIELGTNRTP LACIQRYQRS LNSKMMKREW
TKEEDEVLAG VIKLHMHGER IDWQEITEYI PGRTGHQCLH RWHKTLDPSI KKGRWSPEED
QCLINAVNAY GKGNWILIKN HVKGRTDVQC RERYCNVLDP QLTKIRWTPQ EDKRLFDITN
KVGIGKWSDV AKLMENRTDN QCWRRWKQLN KSSNVLKDYQ EKVSKKKEIC VSNFSGRKHE
RSELTVDDVI EIEEKLNPKS NKKTKTLTST TTTSTNPTTN NNKTDNIDNQ CGKNNDCSTF
CGIDDHYDDE LLQKD
