MYBM_DICDI
ID MYBM_DICDI Reviewed; 669 AA.
AC Q55GK3;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 102.
DE RecName: Full=Myb-like protein M;
GN Name=mybM; ORFNames=DDB_G0267636;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
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DR EMBL; AAFI02000003; EAL73271.1; -; Genomic_DNA.
DR RefSeq; XP_647181.1; XM_642089.1.
DR AlphaFoldDB; Q55GK3; -.
DR SMR; Q55GK3; -.
DR STRING; 44689.DDB0220517; -.
DR PaxDb; Q55GK3; -.
DR PRIDE; Q55GK3; -.
DR EnsemblProtists; EAL73271; EAL73271; DDB_G0267636.
DR GeneID; 8615985; -.
DR KEGG; ddi:DDB_G0267636; -.
DR dictyBase; DDB_G0267636; mybM.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_410746_0_0_1; -.
DR InParanoid; Q55GK3; -.
DR OMA; AKRICKR; -.
DR PRO; PR:Q55GK3; -.
DR Proteomes; UP000002195; Chromosome 1.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SMART; SM00717; SANT; 3.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
DR PROSITE; PS50090; MYB_LIKE; 1.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..669
FT /note="Myb-like protein M"
FT /id="PRO_0000328227"
FT DOMAIN 60..118
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 119..170
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 172..223
FT /note="Myb-like"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00133"
FT DNA_BIND 90..114
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 142..166
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 27..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..596
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..636
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 669 AA; 76035 MW; 21910008153890BD CRC64;
MTESLIMNNI SKYNISPQFN SDRIYNDPSL MDDEFSDNEY DLSPKDDVPS PSKRGRGQIQ
NGIRRSPNKW TEEEDQKLFQ LVSIYGEKKW KRISAEMGGQ KTGAQCAQHW KRVLSPDIRK
GPWDEDEEEL LLRLVNQHGS SWKKIAKRIC KRTDIQCRYQ YLKSLQSREV AWVPKEDEVL
VKKVDEMGEN LSWLEVSEYL AKLKHTNTLR TALECKTRYL QLTGKGGSIL PPLNQSNVSS
LNSSSANTFN QQLQYQQQQQ QQQQQQQQQQ QQQQQQMNNN YNNNYNNNNN NINNNYNNNH
NNQNNNNNNN HNHYNNHYNQ MNNNNNNNHY NNNNNNNNNI NNNNNNNMYQ MNNNNSNSNN
NNKSHNLSPL SSIIDSNTSS PSFEGCEDNN NNNNNNNNNN NNNNNNNNNN NNSNNTPPNI
FRPLPHKPVV TGLTSPTSSP IPSSPPLTPP TSLTLPSSTL SSPSCNNSIR QPSPSPSIKT
FKSTIVSTPS RPSPSSSTNS AFSINNIIDS ENNNNNNNND NDNIKVEDNG CNEPVMKKVR
SNGEFYYQPI KNKLNNNNNN NNNNNNNNNN NNNNNNNNNN NNGNNTLSYN SDNSSDDDML
PKLKNNKQIL SNFKNHNNNQ SNTSPMSSPI SSPHQSSIEK LKATSFDFFK LESLATLASQ
SQIVNELVN
