MYBQ_DICDI
ID MYBQ_DICDI Reviewed; 909 AA.
AC Q54HP1;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Myb-like protein Q;
GN Name=mybQ; ORFNames=DDB_G0289319;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
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DR EMBL; AAFI02000138; EAL62782.1; -; Genomic_DNA.
DR RefSeq; XP_636296.1; XM_631204.1.
DR AlphaFoldDB; Q54HP1; -.
DR SMR; Q54HP1; -.
DR STRING; 44689.DDB0216341; -.
DR PaxDb; Q54HP1; -.
DR EnsemblProtists; EAL62782; EAL62782; DDB_G0289319.
DR GeneID; 8627079; -.
DR KEGG; ddi:DDB_G0289319; -.
DR dictyBase; DDB_G0289319; mybQ.
DR eggNOG; KOG0048; Eukaryota.
DR HOGENOM; CLU_319698_0_0_1; -.
DR InParanoid; Q54HP1; -.
DR OMA; GIVKGPW; -.
DR PRO; PR:Q54HP1; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000278; P:mitotic cell cycle; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR CDD; cd00167; SANT; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
PE 3: Inferred from homology;
KW DNA-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..909
FT /note="Myb-like protein Q"
FT /id="PRO_0000329390"
FT DOMAIN 272..327
FT /note="HTH myb-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DOMAIN 328..378
FT /note="HTH myb-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 300..323
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 351..374
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 15..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 84..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..855
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 216..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..482
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 103811 MW; 075676151F687B51 CRC64;
MLYCGSTGGH YMIMTTNNNS NNNNNNNNNN NNNNNNNNNN NINQNHQHQH QHHHHQQQQQ
QQQQQQQQQQ QQQQQQQQQQ QQQQQQNYGE STTSTSMIPP SITTSLTPLT PTLSSQPQNI
QQQQQQQHHH QQQHHHHHQQ TQQQQQQILS PMMGSKRKLE EDMGVGQPTS NLTNEYLMSN
NNSLKPILVS SPLLTPLSAS PGLTSMQMAF ANASLSAPST PLSMSPSLGP CSAPMSPSKK
SKNSRSSSKS KYQNSEERWQ STTSKDNGKP SSPGIVKGPW KDEEDAKLVE LVNKCGPKEW
SSIAAKIPGR IGKQCRERWF NHLSPEVRKT NWTPEEDKII IDAHASLGNK WTAISKMLDG
RPANAIKNHW NSTLLKKIGG DSKSLNKEKD DDDDDDEDAE DGSSPVLSPI SLYQSSSSTT
TTTTTTTTNS SEKSNIPPFA LSGSTTTSTN NLNNSTNSTN SINNNNNNNN NNNNSSNTNT
AITTNEPLVA PKIIRAQTTP NSSPSLSSKK THDKQKVPQS PKNSKQQQTQ QQTQQQTQQQ
LQQQQQQQQQ QQQQQQQQQQ QQHIQQQQMP VISQQPHIQQ LPIDQQIQNA QFQQFHLQQP
SMPSSTSVNI IPNQSSMEQH HYQQQQQAQQ QQHQQQQHQQ QQQHQQQQQQ QQYLMQQHQQ
YQQQYQLMQQ HYQQQLSQQH HQQQHHPQQA QQHHPQQVQH HQQHINTTHN QHQQQQQQQQ
QQQQQQTNNS QVNSNNTDTT FSNSHPIEPH EVPYYYDYWG SSTSGSQTLI PSDNTTNTYT
IENNNDFLLF DDNQHRIQPL QQHQHIKQEH AQMSHLPYHP TQPNNLNTTT TTTNNNNNNN
NNNNNNNNNN NIPTPNMSAS TTGTINHHIH QTHHHLTTPL SQSTPSVSTD QNNYINYDIS
SLFSLPNEI
