ID   MYCBP_BOVIN             Reviewed;         103 AA.
AC   Q2TBP7;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=c-Myc-binding protein;
DE   AltName: Full=Associate of Myc 1;
DE            Short=AMY-1;
GN   Name=MYCBP; Synonyms=AMY1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May control the transcriptional activity of MYC. Stimulates
CC       the activation of E box-dependent transcription by MYC (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Binds via its C-terminal region to the N-terminal region of
CC       MYC. Associates with AKAP1/S-AKAP84. Interacts with MYCBPAP. Interacts
CC       with CFAP91. {ECO:0000250|UniProtKB:Q99417}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=Translocates into the nucleus in the S phase of the cell cycle.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AMY1 family. {ECO:0000305}.
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DR   EMBL; BC109848; AAI09849.1; -; mRNA.
DR   RefSeq; NP_001033654.1; NM_001038565.2.
DR   AlphaFoldDB; Q2TBP7; -.
DR   SMR; Q2TBP7; -.
DR   STRING; 9913.ENSBTAP00000040445; -.
DR   PaxDb; Q2TBP7; -.
DR   PeptideAtlas; Q2TBP7; -.
DR   PRIDE; Q2TBP7; -.
DR   GeneID; 539291; -.
DR   KEGG; bta:539291; -.
DR   CTD; 26292; -.
DR   eggNOG; ENOG502S2IC; Eukaryota.
DR   HOGENOM; CLU_135895_0_1_1; -.
DR   InParanoid; Q2TBP7; -.
DR   OrthoDB; 1497203at2759; -.
DR   TreeFam; TF329224; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   InterPro; IPR026060; AMY1.
DR   PANTHER; PTHR13168; PTHR13168; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..103
FT                   /note="c-Myc-binding protein"
FT                   /id="PRO_0000249728"
SQ   SEQUENCE   103 AA;  11997 MW;  7309BD179A6808C0 CRC64;
     MAHYKAADSK REQFRRYLEK SGVLDTLTKV LVALYEEPEK PNSALDFLKH HLGAATPENP
     EIELLRLELA EMKEKYEAIV EENKKLKTKL AQYEPPQEEK RAE