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MYCBP_PONAB
ID   MYCBP_PONAB             Reviewed;         103 AA.
AC   Q5R7A8;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=c-Myc-binding protein;
DE   AltName: Full=Associate of Myc 1;
DE            Short=AMY-1;
GN   Name=MYCBP; Synonyms=AMY1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May control the transcriptional activity of MYC. Stimulates
CC       the activation of E box-dependent transcription by MYC (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Binds via its C-terminal region to the N-terminal region of
CC       MYC. Associates with AKAP1/S-AKAP84. Interacts with MYCBPAP. Interacts
CC       with CFAP91. {ECO:0000250|UniProtKB:Q99417}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Note=Translocates into the nucleus in the S phase of the cell cycle.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AMY1 family. {ECO:0000305}.
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DR   EMBL; CR860210; CAH92352.1; -; mRNA.
DR   RefSeq; NP_001128990.1; NM_001135518.1.
DR   AlphaFoldDB; Q5R7A8; -.
DR   SMR; Q5R7A8; -.
DR   STRING; 9601.ENSPPYP00000001751; -.
DR   Ensembl; ENSPPYT00000001808; ENSPPYP00000001751; ENSPPYG00000001515.
DR   GeneID; 100190830; -.
DR   KEGG; pon:100190830; -.
DR   CTD; 26292; -.
DR   eggNOG; ENOG502S2IC; Eukaryota.
DR   GeneTree; ENSGT00390000017974; -.
DR   HOGENOM; CLU_135895_0_1_1; -.
DR   InParanoid; Q5R7A8; -.
DR   OrthoDB; 1497203at2759; -.
DR   Proteomes; UP000001595; Chromosome 1.
DR   GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR   InterPro; IPR026060; AMY1.
DR   PANTHER; PTHR13168; PTHR13168; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..103
FT                   /note="c-Myc-binding protein"
FT                   /id="PRO_0000249729"
SQ   SEQUENCE   103 AA;  11949 MW;  1ED37D179A6808D4 CRC64;
     MAHYKAADSK REQFRRYLEK SGVLDTLTKV LVALYEEPEK PNSALDFLKH HLGAATPENP
     EIELLRLELA EIKEKYEAIV EENKKLKAKL AQYEPPQEEK RAE
 
 
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