MYCBP_PONAB
ID MYCBP_PONAB Reviewed; 103 AA.
AC Q5R7A8;
DT 19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=c-Myc-binding protein;
DE AltName: Full=Associate of Myc 1;
DE Short=AMY-1;
GN Name=MYCBP; Synonyms=AMY1;
OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pongo.
OX NCBI_TaxID=9601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG The German cDNA consortium;
RL Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May control the transcriptional activity of MYC. Stimulates
CC the activation of E box-dependent transcription by MYC (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Binds via its C-terminal region to the N-terminal region of
CC MYC. Associates with AKAP1/S-AKAP84. Interacts with MYCBPAP. Interacts
CC with CFAP91. {ECO:0000250|UniProtKB:Q99417}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC Note=Translocates into the nucleus in the S phase of the cell cycle.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the AMY1 family. {ECO:0000305}.
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DR EMBL; CR860210; CAH92352.1; -; mRNA.
DR RefSeq; NP_001128990.1; NM_001135518.1.
DR AlphaFoldDB; Q5R7A8; -.
DR SMR; Q5R7A8; -.
DR STRING; 9601.ENSPPYP00000001751; -.
DR Ensembl; ENSPPYT00000001808; ENSPPYP00000001751; ENSPPYG00000001515.
DR GeneID; 100190830; -.
DR KEGG; pon:100190830; -.
DR CTD; 26292; -.
DR eggNOG; ENOG502S2IC; Eukaryota.
DR GeneTree; ENSGT00390000017974; -.
DR HOGENOM; CLU_135895_0_1_1; -.
DR InParanoid; Q5R7A8; -.
DR OrthoDB; 1497203at2759; -.
DR Proteomes; UP000001595; Chromosome 1.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; ISS:UniProtKB.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR InterPro; IPR026060; AMY1.
DR PANTHER; PTHR13168; PTHR13168; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..103
FT /note="c-Myc-binding protein"
FT /id="PRO_0000249729"
SQ SEQUENCE 103 AA; 11949 MW; 1ED37D179A6808D4 CRC64;
MAHYKAADSK REQFRRYLEK SGVLDTLTKV LVALYEEPEK PNSALDFLKH HLGAATPENP
EIELLRLELA EIKEKYEAIV EENKKLKAKL AQYEPPQEEK RAE