MYCB_RAT
ID MYCB_RAT Reviewed; 168 AA.
AC P15063; Q3HVJ5;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 3.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=Protein B-Myc;
GN Name=Mycb; Synonyms=Bmyc;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Sprague-Dawley; TISSUE=Brain, and Liver;
RX PubMed=2687773;
RA Asker C., Steinitz M., Andersson K., Suemegi J., Klein G., Ingvarsson S.;
RT "Nucleotide sequence of the rat Bmyc gene.";
RL Oncogene 4:1523-1527(1989).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=ACI/SegHsd, Brown Norway/SsNHsd, COP/CrCrl, DA, and Fischer 344;
RC TISSUE=Spleen;
RA Hansen K.K., McIvor K.J., Streblow R.C., Shull J.D.;
RT "Evaluation of B-myc as a candidate for Ept6.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-120.
RX PubMed=2850482; DOI=10.1128/mcb.8.8.3168-3174.1988;
RA Ingvarsson S., Asker C., Axelson H., Klein G., Suemegi J.;
RT "Structure and expression of B-myc, a new member of the myc gene family.";
RL Mol. Cell. Biol. 8:3168-3174(1988).
CC -!- FUNCTION: Seems to act as an inhibitor of cellular proliferation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA35499.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; X17455; CAA35499.1; ALT_FRAME; Genomic_DNA.
DR EMBL; DQ191783; ABA40415.1; -; mRNA.
DR EMBL; DQ191784; ABA40416.1; -; mRNA.
DR EMBL; DQ191785; ABA40417.1; -; mRNA.
DR EMBL; DQ191786; ABA40418.1; -; mRNA.
DR EMBL; DQ191782; ABA40414.1; -; mRNA.
DR EMBL; M21133; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; A45502; TVRTBM.
DR RefSeq; NP_001013181.2; NM_001013163.2.
DR AlphaFoldDB; P15063; -.
DR STRING; 10116.ENSRNOP00000059721; -.
DR PhosphoSitePlus; P15063; -.
DR PaxDb; P15063; -.
DR Ensembl; ENSRNOT00000064358; ENSRNOP00000059721; ENSRNOG00000042556.
DR GeneID; 311807; -.
DR KEGG; rno:311807; -.
DR UCSC; RGD:1584970; rat.
DR CTD; 107771; -.
DR RGD; 1584970; Bmyc.
DR eggNOG; KOG2483; Eukaryota.
DR GeneTree; ENSGT00940000155285; -.
DR HOGENOM; CLU_135109_0_0_1; -.
DR InParanoid; P15063; -.
DR OMA; PDCTCNT; -.
DR OrthoDB; 877891at2759; -.
DR PhylomeDB; P15063; -.
DR PRO; PR:P15063; -.
DR Proteomes; UP000002494; Chromosome 3.
DR Bgee; ENSRNOG00000042556; Expressed in cerebellum and 20 other tissues.
DR Genevisible; P15063; RN.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:Ensembl.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR002418; Tscrpt_reg_Myc.
DR InterPro; IPR012682; Tscrpt_reg_Myc_N.
DR Pfam; PF01056; Myc_N; 1.
DR PRINTS; PR00044; LEUZIPPRMYC.
PE 2: Evidence at transcript level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..168
FT /note="Protein B-Myc"
FT /id="PRO_0000127340"
FT REGION 26..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 59
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6P8Z1"
FT MOD_RES 67
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6P8Z1"
SQ SEQUENCE 168 AA; 18317 MW; B7BD2FA88D0D052C CRC64;
MPLHVSLANG NRDLDYDSVQ PYFMCDDEEE DVHQQPPQPP APSEDIWKKF ELLPTPRPSP
GHPGLYSPPC EAVAASFSPR DHDGDSFSTA DLPELPGDAV KQSFVCDPDD ETFVKNIILQ
DCMWNGFSAS AKLVSKLDPY QAVRKEGASV SPAADVEPAT PPDCTCNT
