ID   MYCII_MICGR             Reviewed;          74 AA.
AC   Q83WF4;
DT   11-NOV-2015, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Ferredoxin MycCII {ECO:0000303|PubMed:18804032};
DE   AltName: Full=Mycinamicin biosynthesis protein CII {ECO:0000305|PubMed:12583909};
GN   Name=mycCII {ECO:0000303|PubMed:12583909};
OS   Micromonospora griseorubida.
OC   Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
OC   Micromonospora.
OX   NCBI_TaxID=28040;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12583909; DOI=10.1111/j.1574-6968.2003.tb11509.x;
RA   Anzai Y., Saito N., Tanaka M., Kinoshita K., Koyama Y., Kato F.;
RT   "Organization of the biosynthetic gene cluster for the polyketide macrolide
RT   mycinamicin in Micromonospora griseorubida.";
RL   FEMS Microbiol. Lett. 218:135-141(2003).
RN   [2]
RP   FUNCTION, AND PATHWAY.
RX   PubMed=18804032; DOI=10.1016/j.chembiol.2008.07.014;
RA   Anzai Y., Li S., Chaulagain M.R., Kinoshita K., Kato F., Montgomery J.,
RA   Sherman D.H.;
RT   "Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in
RT   biosynthesis of mycinamicin macrolide antibiotics.";
RL   Chem. Biol. 15:950-959(2008).
CC   -!- FUNCTION: Specific electron transport protein capable of effectively
CC       supporting cytochrome P450 MycCI activity in the biosynthesis of
CC       mycinamicin, a 16-membered macrolide antibiotic.
CC       {ECO:0000269|PubMed:18804032}.
CC   -!- COFACTOR:
CC       Name=[3Fe-4S] cluster; Xref=ChEBI:CHEBI:21137; Evidence={ECO:0000250};
CC       Note=Binds 1 [3Fe-4S] cluster. {ECO:0000250};
CC   -!- PATHWAY: Antibiotic biosynthesis; mycinamicin biosynthesis.
CC       {ECO:0000305|PubMed:18804032}.
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DR   EMBL; AB089954; BAC57024.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q83WF4; -.
DR   SMR; Q83WF4; -.
DR   KEGG; ag:BAC57024; -.
DR   BioCyc; MetaCyc:MON-18370; -.
DR   UniPathway; UPA01019; -.
DR   GO; GO:0051538; F:3 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001080; 3Fe4S_ferredoxin.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   PRINTS; PR00352; 3FE4SFRDOXIN.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   3: Inferred from homology;
KW   3Fe-4S; Antibiotic biosynthesis; Electron transport; Iron; Iron-sulfur;
KW   Metal-binding; Transport.
FT   CHAIN           1..74
FT                   /note="Ferredoxin MycCII"
FT                   /id="PRO_0000434766"
FT   DOMAIN          1..29
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT   BINDING         10
FT                   /ligand="[3Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:21137"
FT                   /evidence="ECO:0000250"
FT   BINDING         16
FT                   /ligand="[3Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:21137"
FT                   /evidence="ECO:0000250"
FT   BINDING         54
FT                   /ligand="[3Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:21137"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   74 AA;  7890 MW;  EF48AB4413CE49F7 CRC64;
     MRIVLDAERC VGAGQCEATA PELFTQGDDG LGLVRDRPVT PELLGPAREA VDRCPVRAIR
     IESSVRTGWA RGAG