ID   MYG_CHICK               Reviewed;         154 AA.
AC   P02197; P02198;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 4.
DT   03-AUG-2022, entry version 137.
DE   RecName: Full=Myoglobin;
GN   Name=MB;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-154.
RX   PubMed=3427916; DOI=10.1016/0305-0491(87)90244-6;
RA   Matsuoka A., Iwaasa H., Takiguchi K., Arakawa N., Li L., Takagi T.,
RA   Shikama K.;
RT   "Stability properties of oxymyoglobin from chicken gizzard smooth muscle.";
RL   Comp. Biochem. Physiol. 88B:783-789(1987).
RN   [2]
RP   PRELIMINARY PROTEIN SEQUENCE OF 2-154.
RX   PubMed=1169972; DOI=10.1016/0005-2795(75)90300-1;
RA   Deconinck M., Peiffer S., Depreter J., Paul C., Schnek A.G., Leonis J.;
RT   "The primary sequence of chicken myoglobin (Gallus gallus).";
RL   Biochim. Biophys. Acta 386:567-575(1975).
RN   [3]
RP   SEQUENCE REVISION.
RC   TISSUE=Heart muscle;
RX   PubMed=6838896; DOI=10.1016/0167-4838(83)90287-x;
RA   Prass W.A., Berkley D.S., Romero-Herrera A.E.;
RT   "Chicken cardiac myoglobin revisited.";
RL   Biochim. Biophys. Acta 742:677-680(1983).
CC   -!- FUNCTION: Serves as a reserve supply of oxygen and facilitates the
CC       movement of oxygen within muscles.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   PIR; A60792; MYCH.
DR   RefSeq; NP_001161224.1; NM_001167752.2.
DR   AlphaFoldDB; P02197; -.
DR   SMR; P02197; -.
DR   STRING; 9031.ENSGALP00000020457; -.
DR   CarbonylDB; P02197; -.
DR   PaxDb; P02197; -.
DR   Ensembl; ENSGALT00000020484; ENSGALP00000020457; ENSGALG00000012541.
DR   GeneID; 418056; -.
DR   KEGG; gga:418056; -.
DR   CTD; 4151; -.
DR   VEuPathDB; HostDB:geneid_418056; -.
DR   eggNOG; KOG3378; Eukaryota.
DR   GeneTree; ENSGT00940000160809; -.
DR   HOGENOM; CLU_003827_18_0_1; -.
DR   InParanoid; P02197; -.
DR   OMA; MRLFQDH; -.
DR   OrthoDB; 1405713at2759; -.
DR   PhylomeDB; P02197; -.
DR   TreeFam; TF332967; -.
DR   Reactome; R-GGA-8981607; Intracellular oxygen transport.
DR   PRO; PR:P02197; -.
DR   Proteomes; UP000000539; Chromosome 1.
DR   Bgee; ENSGALG00000012541; Expressed in heart and 5 other tissues.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IBA:GO_Central.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   GO; GO:0043353; P:enucleate erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0007507; P:heart development; IEA:Ensembl.
DR   GO; GO:0015671; P:oxygen transport; IBA:GO_Central.
DR   GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR002335; Myoglobin.
DR   PANTHER; PTHR47132; PTHR47132; 1.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00613; MYOGLOBIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Heme; Iron; Metal-binding; Muscle protein;
KW   Oxygen transport; Reference proteome; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:3427916"
FT   CHAIN           2..154
FT                   /note="Myoglobin"
FT                   /id="PRO_0000053356"
FT   BINDING         65
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT   BINDING         94
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT   CONFLICT        54..55
FT                   /note="DQ -> NE (in Ref. 3)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        82
FT                   /note="N -> Q (in Ref. 3)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        86
FT                   /note="E -> D (in Ref. 3)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   154 AA;  17422 MW;  AE8AEA7C9E83BCD5 CRC64;
     MGLSDQEWQQ VLTIWGKVEA DIAGHGHEVL MRLFHDHPET LDRFDKFKGL KTPDQMKGSE
     DLKKHGATVL TQLGKILKQK GNHESELKPL AQTHATKHKI PVKYLEFISE VIIKVIAEKH
     AADFGADSQA AMKKALELFR NDMASKYKEF GFQG