ID   MYG_DANRE               Reviewed;         147 AA.
AC   Q6VN46; Q6P028;
DT   25-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Myoglobin;
GN   Name=mb; ORFNames=zgc:65819;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=15050521; DOI=10.1016/j.cbpc.2003.12.008;
RA   Madden P.W., Babcock M.J., Vayda M.E., Cashon R.E.;
RT   "Structural and kinetic characterization of myoglobins from eurythermal and
RT   stenothermal fish species.";
RL   Comp. Biochem. Physiol. 137B:341-350(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Serves as a reserve supply of oxygen and facilitates the
CC       movement of oxygen within muscles.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   EMBL; AY337025; AAR00323.1; -; mRNA.
DR   EMBL; BC056727; AAH56727.1; -; mRNA.
DR   EMBL; BC065862; AAH65862.1; -; mRNA.
DR   RefSeq; NP_956880.1; NM_200586.1.
DR   RefSeq; XP_005160224.1; XM_005160167.3.
DR   RefSeq; XP_005160225.1; XM_005160168.3.
DR   AlphaFoldDB; Q6VN46; -.
DR   SMR; Q6VN46; -.
DR   STRING; 7955.ENSDARP00000120315; -.
DR   PaxDb; Q6VN46; -.
DR   PRIDE; Q6VN46; -.
DR   Ensembl; ENSDART00000039807; ENSDARP00000039806; ENSDARG00000031952.
DR   Ensembl; ENSDART00000133472; ENSDARP00000116402; ENSDARG00000031952.
DR   Ensembl; ENSDART00000136378; ENSDARP00000120315; ENSDARG00000031952.
DR   Ensembl; ENSDART00000138070; ENSDARP00000120260; ENSDARG00000031952.
DR   GeneID; 393558; -.
DR   KEGG; dre:393558; -.
DR   CTD; 4151; -.
DR   ZFIN; ZDB-GENE-040426-1430; mb.
DR   eggNOG; KOG3378; Eukaryota.
DR   GeneTree; ENSGT00940000160809; -.
DR   InParanoid; Q6VN46; -.
DR   OMA; MRLFQDH; -.
DR   OrthoDB; 1405713at2759; -.
DR   PhylomeDB; Q6VN46; -.
DR   TreeFam; TF332967; -.
DR   Reactome; R-DRE-8981607; Intracellular oxygen transport.
DR   PRO; PR:Q6VN46; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 1.
DR   Bgee; ENSDARG00000031952; Expressed in cardiac ventricle and 64 other tissues.
DR   ExpressionAtlas; Q6VN46; baseline and differential.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IBA:GO_Central.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   GO; GO:0048565; P:digestive tract development; IMP:ZFIN.
DR   GO; GO:0015671; P:oxygen transport; IBA:GO_Central.
DR   GO; GO:0014823; P:response to activity; IDA:ZFIN.
DR   GO; GO:0001666; P:response to hypoxia; IDA:ZFIN.
DR   GO; GO:0001570; P:vasculogenesis; IMP:ZFIN.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR002335; Myoglobin.
DR   PANTHER; PTHR47132; PTHR47132; 1.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00613; MYOGLOBIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   2: Evidence at transcript level;
KW   Heme; Iron; Metal-binding; Muscle protein; Oxygen transport;
KW   Reference proteome; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..147
FT                   /note="Myoglobin"
FT                   /id="PRO_0000053360"
FT   BINDING         60
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT   BINDING         89
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
FT   CONFLICT        137
FT                   /note="D -> G (in Ref. 1; AAR00323)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   147 AA;  15583 MW;  9866FEE18813EF9D CRC64;
     MADHDLVLKC WGAVEADYAA NGGEVLNRLF KEYPDTLKLF PKFSGISQGD LAGSPAVAAH
     GATVLKKLGE LLKAKGDHAA LLKPLANTHA NIHKVALNNF RLITEVLVKV MAEKAGLDAA
     GQGALRRVMD AVIGDIDGYY KEIGFAG