MYG_PHYMC
ID MYG_PHYMC Reviewed; 154 AA.
AC P02185; Q0KIY8;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 173.
DE RecName: Full=Myoglobin;
GN Name=MB;
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16962803; DOI=10.1016/j.cbpb.2006.08.002;
RA Iwanami K., Mita H., Yamamoto Y., Fujise Y., Yamada T., Suzuki T.;
RT "cDNA-derived amino acid sequences of myoglobins from nine species of
RT whales and dolphins.";
RL Comp. Biochem. Physiol. 145B:249-256(2006).
RN [2]
RP PROTEIN SEQUENCE OF 2-154.
RC TISSUE=Heart muscle;
RA Edmundson A.B.;
RT "Amino-acid sequence of sperm whale myoglobin.";
RL Nature 205:883-887(1965).
RN [3]
RP SEQUENCE REVISION TO 123.
RC TISSUE=Skeletal muscle;
RA Romero-Herrera A.E., Lehmann H.;
RT "Residue 122 of sperm whale and horse myoglobin.";
RL Biochim. Biophys. Acta 336:318-323(1974).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF METMYOGLOBIN.
RX PubMed=845959; DOI=10.1016/s0022-2836(77)80111-3;
RA Takano T.;
RT "Structure of myoglobin refined at 2.0-A resolution. I. Crystallographic
RT refinement of metmyoglobin from sperm whale.";
RL J. Mol. Biol. 110:537-568(1977).
RN [5]
RP X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF DEOXYMYOGLOBIN.
RX PubMed=845960; DOI=10.1016/s0022-2836(77)80112-5;
RA Takano T.;
RT "Structure of myoglobin refined at 2.0-A resolution. II. Structure of
RT deoxymyoglobin from sperm whale.";
RL J. Mol. Biol. 110:569-584(1977).
RN [6]
RP X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) OF OXYMYOGLOBIN.
RX PubMed=7463482; DOI=10.1016/0022-2836(80)90262-4;
RA Phillips S.E.V.;
RT "Structure and refinement of oxymyoglobin at 1.6-A resolution.";
RL J. Mol. Biol. 142:531-554(1980).
RN [7]
RP X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS).
RX PubMed=1994031; DOI=10.1016/0022-2836(91)90744-q;
RA Lionetti C., Guanziroli M.G., Frigerio F., Ascenzi P., Bolognesi M.;
RT "X-ray crystal structure of the ferric sperm whale myoglobin: imidazole
RT complex at 2.0-A resolution.";
RL J. Mol. Biol. 217:409-412(1991).
RN [8]
RP X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS).
RX PubMed=10049310; DOI=10.1016/s0006-3495(99)77289-9;
RA Brunori M., Cutruzzola F., Savino C., Travaglini-Allocatelli C.,
RA Vallone B., Gibson Q.H.;
RT "Structural dynamics of ligand diffusion in the protein matrix: a study on
RT a new myoglobin mutant Y(B10) Q(E7) R(E10).";
RL Biophys. J. 76:1259-1269(1999).
RN [9]
RP X-RAY CRYSTALLOGRAPHY (1.4 ANGSTROMS).
RX PubMed=10681426; DOI=10.1073/pnas.040459697;
RA Brunori M., Vallone B., Cutruzzola F., Travaglini-Allocatelli C.,
RA Berendzen J., Chu K., Sweet R.M., Schlichting I.;
RT "The role of cavities in protein dynamics: crystal structure of a
RT photolytic intermediate of a mutant myoglobin.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:2058-2063(2000).
CC -!- FUNCTION: Serves as a reserve supply of oxygen and facilitates the
CC movement of oxygen within muscles.
CC -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC ProRule:PRU00238}.
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DR EMBL; AB271144; BAF03579.1; -; mRNA.
DR PIR; A90591; MYWHP.
DR RefSeq; NP_001277651.1; NM_001290722.1.
DR PDB; 101M; X-ray; 2.07 A; A=1-154.
DR PDB; 102M; X-ray; 1.84 A; A=1-154.
DR PDB; 103M; X-ray; 2.07 A; A=1-154.
DR PDB; 104M; X-ray; 1.71 A; A=2-154.
DR PDB; 105M; X-ray; 2.02 A; A=2-154.
DR PDB; 106M; X-ray; 1.99 A; A=1-154.
DR PDB; 107M; X-ray; 2.09 A; A=1-154.
DR PDB; 108M; X-ray; 2.67 A; A=1-154.
DR PDB; 109M; X-ray; 1.83 A; A=1-154.
DR PDB; 110M; X-ray; 1.77 A; A=1-154.
DR PDB; 111M; X-ray; 1.88 A; A=1-154.
DR PDB; 112M; X-ray; 2.34 A; A=1-154.
DR PDB; 1A6G; X-ray; 1.15 A; A=2-152.
DR PDB; 1A6K; X-ray; 1.10 A; A=2-152.
DR PDB; 1A6M; X-ray; 1.00 A; A=2-152.
DR PDB; 1A6N; X-ray; 1.15 A; A=2-152.
DR PDB; 1ABS; X-ray; 1.50 A; A=1-154.
DR PDB; 1AJG; X-ray; 1.69 A; A=2-154.
DR PDB; 1AJH; X-ray; 1.69 A; A=2-154.
DR PDB; 1BVC; X-ray; 1.50 A; A=2-154.
DR PDB; 1BVD; X-ray; 1.40 A; A=2-154.
DR PDB; 1BZ6; X-ray; 1.20 A; A=2-154.
DR PDB; 1BZP; X-ray; 1.15 A; A=2-154.
DR PDB; 1BZR; X-ray; 1.15 A; A=2-154.
DR PDB; 1CH1; X-ray; 1.90 A; A=1-154.
DR PDB; 1CH2; X-ray; 1.80 A; A=2-154.
DR PDB; 1CH3; X-ray; 2.00 A; A=2-154.
DR PDB; 1CH5; X-ray; 2.10 A; A=2-154.
DR PDB; 1CH7; X-ray; 1.90 A; A=2-154.
DR PDB; 1CH9; X-ray; 1.80 A; A=2-154.
DR PDB; 1CIK; X-ray; 1.70 A; A=2-154.
DR PDB; 1CIO; X-ray; 1.60 A; A=2-154.
DR PDB; 1CO8; X-ray; 1.80 A; A=1-154.
DR PDB; 1CO9; X-ray; 1.60 A; A=1-154.
DR PDB; 1CP0; X-ray; 2.00 A; A=1-154.
DR PDB; 1CP5; X-ray; 2.10 A; A=1-154.
DR PDB; 1CPW; X-ray; 2.20 A; A=1-154.
DR PDB; 1CQ2; Neutron; 2.00 A; A=2-154.
DR PDB; 1DO1; X-ray; 1.50 A; A=1-154.
DR PDB; 1DO3; X-ray; 1.55 A; A=1-154.
DR PDB; 1DO4; X-ray; 1.70 A; A=1-154.
DR PDB; 1DO7; X-ray; 1.85 A; A=1-154.
DR PDB; 1DTI; X-ray; 1.70 A; A=1-154.
DR PDB; 1DTM; X-ray; 2.13 A; A=2-154.
DR PDB; 1DUK; X-ray; 2.13 A; A=2-154.
DR PDB; 1DUO; X-ray; 2.00 A; A=2-154.
DR PDB; 1DXC; X-ray; 1.40 A; A=1-154.
DR PDB; 1DXD; X-ray; 1.40 A; A=1-154.
DR PDB; 1EBC; X-ray; 1.80 A; A=2-154.
DR PDB; 1F63; X-ray; 1.80 A; A=1-154.
DR PDB; 1F65; X-ray; 1.70 A; A=1-154.
DR PDB; 1F6H; X-ray; 3.31 A; A=2-154.
DR PDB; 1FCS; X-ray; 1.60 A; A=1-154.
DR PDB; 1H1X; X-ray; 1.40 A; A=2-154.
DR PDB; 1HJT; X-ray; 1.70 A; A=2-154.
DR PDB; 1IOP; X-ray; 1.90 A; A=2-154.
DR PDB; 1IRC; X-ray; 2.17 A; A=1-154.
DR PDB; 1J3F; X-ray; 1.45 A; A=1-154.
DR PDB; 1J52; X-ray; 1.90 A; A=1-154.
DR PDB; 1JDO; X-ray; 1.90 A; A=1-154.
DR PDB; 1JP6; X-ray; 2.30 A; A=2-154.
DR PDB; 1JP8; X-ray; 2.30 A; A=2-154.
DR PDB; 1JP9; X-ray; 1.70 A; A=2-154.
DR PDB; 1JPB; X-ray; 1.70 A; A=2-154.
DR PDB; 1JW8; X-ray; 1.30 A; A=1-154.
DR PDB; 1L2K; Neutron; 1.50 A; A=2-154.
DR PDB; 1LTW; X-ray; 1.70 A; A=1-154.
DR PDB; 1LUE; X-ray; 1.70 A; A=1-154.
DR PDB; 1MBC; X-ray; 1.50 A; A=2-154.
DR PDB; 1MBD; X-ray; 1.40 A; A=2-154.
DR PDB; 1MBI; X-ray; 2.00 A; A=2-154.
DR PDB; 1MBN; X-ray; 2.00 A; A=2-154.
DR PDB; 1MBO; X-ray; 1.60 A; A=2-154.
DR PDB; 1MCY; X-ray; 1.70 A; A=1-154.
DR PDB; 1MGN; X-ray; 1.90 A; A=1-154.
DR PDB; 1MLF; X-ray; 2.00 A; A=1-154.
DR PDB; 1MLG; X-ray; 2.00 A; A=1-154.
DR PDB; 1MLH; X-ray; 2.00 A; A=1-154.
DR PDB; 1MLJ; X-ray; 2.00 A; A=1-154.
DR PDB; 1MLK; X-ray; 1.80 A; A=1-154.
DR PDB; 1MLL; X-ray; 1.70 A; A=1-154.
DR PDB; 1MLM; X-ray; 1.80 A; A=1-154.
DR PDB; 1MLN; X-ray; 2.00 A; A=1-154.
DR PDB; 1MLO; X-ray; 1.80 A; A=1-154.
DR PDB; 1MLQ; X-ray; 2.00 A; A=1-154.
DR PDB; 1MLR; X-ray; 2.00 A; A=1-154.
DR PDB; 1MLS; X-ray; 1.70 A; A=1-154.
DR PDB; 1MLU; X-ray; 1.90 A; A=1-154.
DR PDB; 1MOA; X-ray; 1.90 A; A=1-154.
DR PDB; 1MOB; X-ray; 2.20 A; A=1-154.
DR PDB; 1MOC; X-ray; 2.00 A; A=1-154.
DR PDB; 1MOD; X-ray; 2.00 A; A=1-154.
DR PDB; 1MTI; X-ray; 1.90 A; A=1-154.
DR PDB; 1MTJ; X-ray; 1.70 A; A=1-154.
DR PDB; 1MTK; X-ray; 1.80 A; A=1-154.
DR PDB; 1MYF; NMR; -; A=2-154.
DR PDB; 1MYM; X-ray; 1.70 A; A=1-154.
DR PDB; 1MYZ; X-ray; 1.60 A; A=1-154.
DR PDB; 1MZ0; X-ray; 1.60 A; A=1-154.
DR PDB; 1N9F; X-ray; 1.80 A; A=1-154.
DR PDB; 1N9H; X-ray; 1.80 A; A=1-154.
DR PDB; 1N9I; X-ray; 1.60 A; A=1-154.
DR PDB; 1N9X; X-ray; 1.60 A; A=1-154.
DR PDB; 1NAZ; X-ray; 1.04 A; A=1-154.
DR PDB; 1O16; X-ray; 1.95 A; A=1-154.
DR PDB; 1OBM; X-ray; 1.85 A; A=1-154.
DR PDB; 1OFJ; X-ray; 1.80 A; A=1-154.
DR PDB; 1OFK; X-ray; 1.80 A; A=1-154.
DR PDB; 1SPE; X-ray; 2.00 A; A=2-154.
DR PDB; 1SWM; X-ray; 1.80 A; A=2-154.
DR PDB; 1TES; X-ray; 1.70 A; A=1-154.
DR PDB; 1U7R; X-ray; 1.15 A; A=2-154.
DR PDB; 1U7S; X-ray; 1.40 A; A=2-154.
DR PDB; 1UFJ; X-ray; 1.60 A; A=1-154.
DR PDB; 1UFP; X-ray; 2.10 A; A=1-154.
DR PDB; 1V9Q; X-ray; 1.45 A; A=1-154.
DR PDB; 1VXA; X-ray; 2.00 A; A=2-154.
DR PDB; 1VXB; X-ray; 2.00 A; A=2-154.
DR PDB; 1VXC; X-ray; 1.70 A; A=2-154.
DR PDB; 1VXD; X-ray; 1.70 A; A=2-154.
DR PDB; 1VXE; X-ray; 1.70 A; A=2-154.
DR PDB; 1VXF; X-ray; 1.70 A; A=2-154.
DR PDB; 1VXG; X-ray; 1.70 A; A=2-154.
DR PDB; 1VXH; X-ray; 1.70 A; A=2-154.
DR PDB; 1WVP; X-ray; 1.53 A; A=2-154.
DR PDB; 1YOG; X-ray; 1.65 A; A=2-154.
DR PDB; 1YOH; X-ray; 1.65 A; A=2-154.
DR PDB; 1YOI; X-ray; 1.65 A; A=2-154.
DR PDB; 2BLH; X-ray; 1.77 A; A=2-154.
DR PDB; 2BLI; X-ray; 1.70 A; A=2-154.
DR PDB; 2BLJ; X-ray; 1.80 A; M=2-154.
DR PDB; 2BW9; X-ray; 1.68 A; M=2-154.
DR PDB; 2BWH; X-ray; 1.90 A; A=2-154.
DR PDB; 2CMM; X-ray; 1.80 A; A=2-154.
DR PDB; 2D6C; X-ray; 2.26 A; A/B=2-154.
DR PDB; 2E2Y; X-ray; 1.60 A; A=1-154.
DR PDB; 2EB8; X-ray; 1.65 A; A=1-154.
DR PDB; 2EB9; X-ray; 1.80 A; A=1-154.
DR PDB; 2EF2; X-ray; 1.80 A; A=1-154.
DR PDB; 2EKT; X-ray; 1.10 A; A=2-154.
DR PDB; 2EKU; X-ray; 1.40 A; A=2-154.
DR PDB; 2EVK; X-ray; 1.40 A; A=2-154.
DR PDB; 2EVP; X-ray; 1.70 A; A=2-154.
DR PDB; 2G0R; X-ray; 1.95 A; A=1-154.
DR PDB; 2G0S; X-ray; 1.90 A; A=1-154.
DR PDB; 2G0V; X-ray; 1.95 A; A=1-154.
DR PDB; 2G0X; X-ray; 1.95 A; A=1-154.
DR PDB; 2G0Z; X-ray; 1.95 A; A=1-154.
DR PDB; 2G10; X-ray; 1.90 A; A=1-154.
DR PDB; 2G11; X-ray; 1.90 A; A=1-154.
DR PDB; 2G12; X-ray; 1.90 A; A=1-154.
DR PDB; 2G14; X-ray; 1.90 A; A=1-154.
DR PDB; 2JHO; X-ray; 1.40 A; A=2-154.
DR PDB; 2MB5; Neutron; 1.80 A; A=2-154.
DR PDB; 2MBW; X-ray; 1.50 A; A=1-154.
DR PDB; 2MGA; X-ray; 2.20 A; A=1-154.
DR PDB; 2MGB; X-ray; 2.00 A; A=1-154.
DR PDB; 2MGC; X-ray; 1.90 A; A=1-154.
DR PDB; 2MGD; X-ray; 1.80 A; A=1-154.
DR PDB; 2MGE; X-ray; 1.70 A; A=1-154.
DR PDB; 2MGF; X-ray; 1.80 A; A=1-154.
DR PDB; 2MGG; X-ray; 1.80 A; A=1-154.
DR PDB; 2MGH; X-ray; 2.00 A; A=1-154.
DR PDB; 2MGI; X-ray; 2.00 A; A=1-154.
DR PDB; 2MGJ; X-ray; 2.00 A; A=1-154.
DR PDB; 2MGK; X-ray; 2.00 A; A=1-154.
DR PDB; 2MGL; X-ray; 2.00 A; A=1-154.
DR PDB; 2MGM; X-ray; 1.90 A; A=1-154.
DR PDB; 2MYA; X-ray; 1.80 A; A=2-154.
DR PDB; 2MYB; X-ray; 1.90 A; A=2-154.
DR PDB; 2MYC; X-ray; 1.80 A; A=2-154.
DR PDB; 2MYD; X-ray; 1.80 A; A=2-154.
DR PDB; 2MYE; X-ray; 1.68 A; A=2-154.
DR PDB; 2OH8; X-ray; 1.80 A; A=1-154.
DR PDB; 2OH9; X-ray; 1.80 A; A=1-154.
DR PDB; 2OHA; X-ray; 1.80 A; A=1-154.
DR PDB; 2OHB; X-ray; 1.80 A; A=1-154.
DR PDB; 2SPL; X-ray; 1.70 A; A=1-154.
DR PDB; 2SPM; X-ray; 1.70 A; A=1-154.
DR PDB; 2SPN; X-ray; 1.70 A; A=1-154.
DR PDB; 2SPO; X-ray; 1.70 A; A=1-154.
DR PDB; 2W6W; X-ray; 1.99 A; A=1-154.
DR PDB; 2W6X; X-ray; 1.73 A; A=1-154.
DR PDB; 2W6Y; X-ray; 1.60 A; A=1-154.
DR PDB; 2Z6S; X-ray; 1.25 A; A=2-154.
DR PDB; 2Z6T; X-ray; 1.20 A; A=2-154.
DR PDB; 2ZSN; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSO; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSP; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSQ; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSR; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSS; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZST; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSX; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSY; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZSZ; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZT0; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZT1; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZT2; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZT3; X-ray; 1.21 A; A=2-154.
DR PDB; 2ZT4; X-ray; 1.21 A; A=2-154.
DR PDB; 3A2G; X-ray; 1.75 A; A=1-154.
DR PDB; 3ASE; X-ray; 1.75 A; A=1-154.
DR PDB; 3E4N; X-ray; 1.21 A; A=2-154.
DR PDB; 3E55; X-ray; 1.21 A; A=2-154.
DR PDB; 3E5I; X-ray; 1.22 A; A=2-154.
DR PDB; 3E5O; X-ray; 1.21 A; A=2-154.
DR PDB; 3ECL; X-ray; 1.21 A; A=2-154.
DR PDB; 3ECX; X-ray; 1.21 A; A=2-154.
DR PDB; 3ECZ; X-ray; 1.21 A; A=2-154.
DR PDB; 3ED9; X-ray; 1.21 A; A=2-154.
DR PDB; 3EDA; X-ray; 1.21 A; A=2-154.
DR PDB; 3EDB; X-ray; 1.21 A; A=2-154.
DR PDB; 3H57; X-ray; 1.70 A; A=1-154.
DR PDB; 3H58; X-ray; 1.80 A; A=1-154.
DR PDB; 3K9Z; X-ray; 1.72 A; A=2-154.
DR PDB; 3M38; X-ray; 1.42 A; A=2-154.
DR PDB; 3M39; X-ray; 1.65 A; A=2-154.
DR PDB; 3M3A; X-ray; 1.37 A; A=2-154.
DR PDB; 3M3B; X-ray; 1.60 A; A=2-154.
DR PDB; 3MN0; X-ray; 1.65 A; A=2-154.
DR PDB; 3NML; X-ray; 1.68 A; A=1-154.
DR PDB; 3O89; X-ray; 1.10 A; A=2-154.
DR PDB; 3OGB; X-ray; 1.60 A; A=1-154.
DR PDB; 3SDN; X-ray; 1.50 A; A=1-154.
DR PDB; 3U3E; X-ray; 1.21 A; A=1-154.
DR PDB; 4FWX; X-ray; 1.90 A; A=2-154.
DR PDB; 4FWY; X-ray; 1.80 A; A=2-154.
DR PDB; 4FWZ; X-ray; 1.90 A; A=2-154.
DR PDB; 4H07; X-ray; 1.14 A; A=1-154.
DR PDB; 4H0B; X-ray; 1.26 A; A=1-154.
DR PDB; 4IT8; X-ray; 1.50 A; A=1-154.
DR PDB; 4LPI; X-ray; 1.36 A; A=1-154.
DR PDB; 4MBN; X-ray; 2.00 A; A=2-154.
DR PDB; 4MXK; X-ray; 1.52 A; A=2-154.
DR PDB; 4MXL; X-ray; 1.50 A; A=2-154.
DR PDB; 4NXA; X-ray; 1.60 A; A=1-154.
DR PDB; 4NXC; X-ray; 1.55 A; A=1-154.
DR PDB; 4OF9; X-ray; 1.24 A; A=2-154.
DR PDB; 4OOD; X-ray; 1.24 A; A=1-154.
DR PDB; 4PNJ; X-ray; 1.36 A; A=1-154.
DR PDB; 4PQ6; X-ray; 1.45 A; A=1-154.
DR PDB; 4PQB; X-ray; 1.94 A; A=1-154.
DR PDB; 4PQC; X-ray; 1.50 A; A=1-154.
DR PDB; 4QAU; X-ray; 1.60 A; A=1-154.
DR PDB; 4TYX; X-ray; 1.64 A; A=2-154.
DR PDB; 5B84; X-ray; 1.61 A; A=2-154.
DR PDB; 5B85; X-ray; 1.85 A; A=2-154.
DR PDB; 5C6Y; X-ray; 1.79 A; A=1-154.
DR PDB; 5HAV; X-ray; 1.27 A; A=2-154.
DR PDB; 5HLQ; X-ray; 1.50 A; A=2-154.
DR PDB; 5HLU; X-ray; 1.50 A; A=2-154.
DR PDB; 5HLX; X-ray; 1.50 A; A=2-154.
DR PDB; 5IKS; X-ray; 1.87 A; A=2-152.
DR PDB; 5ILE; X-ray; 1.77 A; A=1-154.
DR PDB; 5ILM; X-ray; 1.70 A; A=1-154.
DR PDB; 5ILP; X-ray; 1.88 A; A=1-154.
DR PDB; 5ILR; X-ray; 1.87 A; A=1-154.
DR PDB; 5JOM; X-ray; 1.90 A; A=1-154.
DR PDB; 5KD1; X-ray; 1.70 A; A=2-154.
DR PDB; 5KKK; X-ray; 1.70 A; A=1-154.
DR PDB; 5M3S; X-ray; 1.80 A; A=1-154.
DR PDB; 5MBN; X-ray; 2.00 A; A=2-154.
DR PDB; 5O41; X-ray; 1.80 A; A=1-154.
DR PDB; 5OJ9; X-ray; 1.48 A; A=1-154.
DR PDB; 5OJA; X-ray; 1.35 A; A=1-154.
DR PDB; 5OJB; X-ray; 1.54 A; A=1-154.
DR PDB; 5OJC; X-ray; 1.25 A; A=1-154.
DR PDB; 5UT7; X-ray; 1.85 A; A=1-154.
DR PDB; 5UT8; X-ray; 1.78 A; A=1-154.
DR PDB; 5UT9; X-ray; 1.85 A; A=1-154.
DR PDB; 5UTA; X-ray; 1.81 A; A=1-154.
DR PDB; 5UTB; X-ray; 1.78 A; A=1-154.
DR PDB; 5UTC; X-ray; 1.80 A; A=1-154.
DR PDB; 5UTD; X-ray; 1.78 A; A=1-154.
DR PDB; 5VNU; X-ray; 1.58 A; A=2-154.
DR PDB; 5VRT; X-ray; 2.00 A; A=2-154.
DR PDB; 5VZN; X-ray; 1.70 A; A=1-154.
DR PDB; 5VZO; X-ray; 1.78 A; A=1-154.
DR PDB; 5VZP; X-ray; 1.78 A; A=1-154.
DR PDB; 5VZQ; X-ray; 1.79 A; A=1-154.
DR PDB; 5WJK; X-ray; 2.00 A; A=1-154.
DR PDB; 5XKV; X-ray; 1.40 A; A=2-154.
DR PDB; 5XKW; X-ray; 1.70 A; A=2-154.
DR PDB; 5XL0; X-ray; 1.25 A; A=2-152.
DR PDB; 5YCE; X-ray; 0.77 A; A=1-154.
DR PDB; 5YCH; X-ray; 1.35 A; A=1-154.
DR PDB; 5YZF; X-ray; 1.77 A; A=1-154.
DR PDB; 5ZEO; X-ray; 1.77 A; A=2-154.
DR PDB; 5ZZF; X-ray; 1.60 A; A=2-154.
DR PDB; 5ZZG; X-ray; 1.80 A; A=2-154.
DR PDB; 6CF0; X-ray; 1.64 A; A=1-154.
DR PDB; 6D45; X-ray; 1.78 A; A=2-154.
DR PDB; 6E02; X-ray; 1.76 A; A=1-154.
DR PDB; 6E03; X-ray; 1.76 A; A=1-154.
DR PDB; 6E04; X-ray; 2.00 A; A=1-154.
DR PDB; 6F17; X-ray; 1.45 A; A=2-154.
DR PDB; 6F18; X-ray; 1.80 A; A=2-154.
DR PDB; 6F19; X-ray; 1.90 A; A=2-154.
DR PDB; 6F1A; X-ray; 2.40 A; A=2-154.
DR PDB; 6G5A; X-ray; 1.48 A; A=1-154.
DR PDB; 6G5B; X-ray; 1.60 A; A=1-154.
DR PDB; 6G5T; X-ray; 1.50 A; A=1-154.
DR PDB; 6JP1; X-ray; 1.99 A; A/B=2-152.
DR PDB; 6KRC; X-ray; 1.39 A; A=2-154.
DR PDB; 6KRF; X-ray; 1.86 A; A=2-154.
DR PDB; 6M8F; X-ray; 1.10 A; A=1-154.
DR PDB; 6MV0; X-ray; 1.97 A; A=1-154.
DR PDB; 6N02; X-ray; 2.00 A; A=1-154.
DR PDB; 6N03; X-ray; 2.10 A; A=1-154.
DR PDB; 6Z4R; X-ray; 1.96 A; A=2-154.
DR PDB; 6Z4T; X-ray; 1.23 A; A=2-154.
DR PDB; 7A44; X-ray; 1.75 A; A=1-154.
DR PDB; 7A45; X-ray; 1.75 A; A=1-154.
DR PDB; 7CEN; X-ray; 2.35 A; A=1-154.
DR PDB; 7CEZ; X-ray; 1.57 A; A=1-154.
DR PDB; 7EHX; X-ray; 1.80 A; A=1-154.
DR PDB; 7KYR; X-ray; 1.71 A; A=1-154.
DR PDB; 7L3U; X-ray; 1.47 A; A=1-154.
DR PDB; 7L3Y; X-ray; 1.18 A; A=1-154.
DR PDBsum; 101M; -.
DR PDBsum; 102M; -.
DR PDBsum; 103M; -.
DR PDBsum; 104M; -.
DR PDBsum; 105M; -.
DR PDBsum; 106M; -.
DR PDBsum; 107M; -.
DR PDBsum; 108M; -.
DR PDBsum; 109M; -.
DR PDBsum; 110M; -.
DR PDBsum; 111M; -.
DR PDBsum; 112M; -.
DR PDBsum; 1A6G; -.
DR PDBsum; 1A6K; -.
DR PDBsum; 1A6M; -.
DR PDBsum; 1A6N; -.
DR PDBsum; 1ABS; -.
DR PDBsum; 1AJG; -.
DR PDBsum; 1AJH; -.
DR PDBsum; 1BVC; -.
DR PDBsum; 1BVD; -.
DR PDBsum; 1BZ6; -.
DR PDBsum; 1BZP; -.
DR PDBsum; 1BZR; -.
DR PDBsum; 1CH1; -.
DR PDBsum; 1CH2; -.
DR PDBsum; 1CH3; -.
DR PDBsum; 1CH5; -.
DR PDBsum; 1CH7; -.
DR PDBsum; 1CH9; -.
DR PDBsum; 1CIK; -.
DR PDBsum; 1CIO; -.
DR PDBsum; 1CO8; -.
DR PDBsum; 1CO9; -.
DR PDBsum; 1CP0; -.
DR PDBsum; 1CP5; -.
DR PDBsum; 1CPW; -.
DR PDBsum; 1CQ2; -.
DR PDBsum; 1DO1; -.
DR PDBsum; 1DO3; -.
DR PDBsum; 1DO4; -.
DR PDBsum; 1DO7; -.
DR PDBsum; 1DTI; -.
DR PDBsum; 1DTM; -.
DR PDBsum; 1DUK; -.
DR PDBsum; 1DUO; -.
DR PDBsum; 1DXC; -.
DR PDBsum; 1DXD; -.
DR PDBsum; 1EBC; -.
DR PDBsum; 1F63; -.
DR PDBsum; 1F65; -.
DR PDBsum; 1F6H; -.
DR PDBsum; 1FCS; -.
DR PDBsum; 1H1X; -.
DR PDBsum; 1HJT; -.
DR PDBsum; 1IOP; -.
DR PDBsum; 1IRC; -.
DR PDBsum; 1J3F; -.
DR PDBsum; 1J52; -.
DR PDBsum; 1JDO; -.
DR PDBsum; 1JP6; -.
DR PDBsum; 1JP8; -.
DR PDBsum; 1JP9; -.
DR PDBsum; 1JPB; -.
DR PDBsum; 1JW8; -.
DR PDBsum; 1L2K; -.
DR PDBsum; 1LTW; -.
DR PDBsum; 1LUE; -.
DR PDBsum; 1MBC; -.
DR PDBsum; 1MBD; -.
DR PDBsum; 1MBI; -.
DR PDBsum; 1MBN; -.
DR PDBsum; 1MBO; -.
DR PDBsum; 1MCY; -.
DR PDBsum; 1MGN; -.
DR PDBsum; 1MLF; -.
DR PDBsum; 1MLG; -.
DR PDBsum; 1MLH; -.
DR PDBsum; 1MLJ; -.
DR PDBsum; 1MLK; -.
DR PDBsum; 1MLL; -.
DR PDBsum; 1MLM; -.
DR PDBsum; 1MLN; -.
DR PDBsum; 1MLO; -.
DR PDBsum; 1MLQ; -.
DR PDBsum; 1MLR; -.
DR PDBsum; 1MLS; -.
DR PDBsum; 1MLU; -.
DR PDBsum; 1MOA; -.
DR PDBsum; 1MOB; -.
DR PDBsum; 1MOC; -.
DR PDBsum; 1MOD; -.
DR PDBsum; 1MTI; -.
DR PDBsum; 1MTJ; -.
DR PDBsum; 1MTK; -.
DR PDBsum; 1MYF; -.
DR PDBsum; 1MYM; -.
DR PDBsum; 1MYZ; -.
DR PDBsum; 1MZ0; -.
DR PDBsum; 1N9F; -.
DR PDBsum; 1N9H; -.
DR PDBsum; 1N9I; -.
DR PDBsum; 1N9X; -.
DR PDBsum; 1NAZ; -.
DR PDBsum; 1O16; -.
DR PDBsum; 1OBM; -.
DR PDBsum; 1OFJ; -.
DR PDBsum; 1OFK; -.
DR PDBsum; 1SPE; -.
DR PDBsum; 1SWM; -.
DR PDBsum; 1TES; -.
DR PDBsum; 1U7R; -.
DR PDBsum; 1U7S; -.
DR PDBsum; 1UFJ; -.
DR PDBsum; 1UFP; -.
DR PDBsum; 1V9Q; -.
DR PDBsum; 1VXA; -.
DR PDBsum; 1VXB; -.
DR PDBsum; 1VXC; -.
DR PDBsum; 1VXD; -.
DR PDBsum; 1VXE; -.
DR PDBsum; 1VXF; -.
DR PDBsum; 1VXG; -.
DR PDBsum; 1VXH; -.
DR PDBsum; 1WVP; -.
DR PDBsum; 1YOG; -.
DR PDBsum; 1YOH; -.
DR PDBsum; 1YOI; -.
DR PDBsum; 2BLH; -.
DR PDBsum; 2BLI; -.
DR PDBsum; 2BLJ; -.
DR PDBsum; 2BW9; -.
DR PDBsum; 2BWH; -.
DR PDBsum; 2CMM; -.
DR PDBsum; 2D6C; -.
DR PDBsum; 2E2Y; -.
DR PDBsum; 2EB8; -.
DR PDBsum; 2EB9; -.
DR PDBsum; 2EF2; -.
DR PDBsum; 2EKT; -.
DR PDBsum; 2EKU; -.
DR PDBsum; 2EVK; -.
DR PDBsum; 2EVP; -.
DR PDBsum; 2G0R; -.
DR PDBsum; 2G0S; -.
DR PDBsum; 2G0V; -.
DR PDBsum; 2G0X; -.
DR PDBsum; 2G0Z; -.
DR PDBsum; 2G10; -.
DR PDBsum; 2G11; -.
DR PDBsum; 2G12; -.
DR PDBsum; 2G14; -.
DR PDBsum; 2JHO; -.
DR PDBsum; 2MB5; -.
DR PDBsum; 2MBW; -.
DR PDBsum; 2MGA; -.
DR PDBsum; 2MGB; -.
DR PDBsum; 2MGC; -.
DR PDBsum; 2MGD; -.
DR PDBsum; 2MGE; -.
DR PDBsum; 2MGF; -.
DR PDBsum; 2MGG; -.
DR PDBsum; 2MGH; -.
DR PDBsum; 2MGI; -.
DR PDBsum; 2MGJ; -.
DR PDBsum; 2MGK; -.
DR PDBsum; 2MGL; -.
DR PDBsum; 2MGM; -.
DR PDBsum; 2MYA; -.
DR PDBsum; 2MYB; -.
DR PDBsum; 2MYC; -.
DR PDBsum; 2MYD; -.
DR PDBsum; 2MYE; -.
DR PDBsum; 2OH8; -.
DR PDBsum; 2OH9; -.
DR PDBsum; 2OHA; -.
DR PDBsum; 2OHB; -.
DR PDBsum; 2SPL; -.
DR PDBsum; 2SPM; -.
DR PDBsum; 2SPN; -.
DR PDBsum; 2SPO; -.
DR PDBsum; 2W6W; -.
DR PDBsum; 2W6X; -.
DR PDBsum; 2W6Y; -.
DR PDBsum; 2Z6S; -.
DR PDBsum; 2Z6T; -.
DR PDBsum; 2ZSN; -.
DR PDBsum; 2ZSO; -.
DR PDBsum; 2ZSP; -.
DR PDBsum; 2ZSQ; -.
DR PDBsum; 2ZSR; -.
DR PDBsum; 2ZSS; -.
DR PDBsum; 2ZST; -.
DR PDBsum; 2ZSX; -.
DR PDBsum; 2ZSY; -.
DR PDBsum; 2ZSZ; -.
DR PDBsum; 2ZT0; -.
DR PDBsum; 2ZT1; -.
DR PDBsum; 2ZT2; -.
DR PDBsum; 2ZT3; -.
DR PDBsum; 2ZT4; -.
DR PDBsum; 3A2G; -.
DR PDBsum; 3ASE; -.
DR PDBsum; 3E4N; -.
DR PDBsum; 3E55; -.
DR PDBsum; 3E5I; -.
DR PDBsum; 3E5O; -.
DR PDBsum; 3ECL; -.
DR PDBsum; 3ECX; -.
DR PDBsum; 3ECZ; -.
DR PDBsum; 3ED9; -.
DR PDBsum; 3EDA; -.
DR PDBsum; 3EDB; -.
DR PDBsum; 3H57; -.
DR PDBsum; 3H58; -.
DR PDBsum; 3K9Z; -.
DR PDBsum; 3M38; -.
DR PDBsum; 3M39; -.
DR PDBsum; 3M3A; -.
DR PDBsum; 3M3B; -.
DR PDBsum; 3MN0; -.
DR PDBsum; 3NML; -.
DR PDBsum; 3O89; -.
DR PDBsum; 3OGB; -.
DR PDBsum; 3SDN; -.
DR PDBsum; 3U3E; -.
DR PDBsum; 4FWX; -.
DR PDBsum; 4FWY; -.
DR PDBsum; 4FWZ; -.
DR PDBsum; 4H07; -.
DR PDBsum; 4H0B; -.
DR PDBsum; 4IT8; -.
DR PDBsum; 4LPI; -.
DR PDBsum; 4MBN; -.
DR PDBsum; 4MXK; -.
DR PDBsum; 4MXL; -.
DR PDBsum; 4NXA; -.
DR PDBsum; 4NXC; -.
DR PDBsum; 4OF9; -.
DR PDBsum; 4OOD; -.
DR PDBsum; 4PNJ; -.
DR PDBsum; 4PQ6; -.
DR PDBsum; 4PQB; -.
DR PDBsum; 4PQC; -.
DR PDBsum; 4QAU; -.
DR PDBsum; 4TYX; -.
DR PDBsum; 5B84; -.
DR PDBsum; 5B85; -.
DR PDBsum; 5C6Y; -.
DR PDBsum; 5HAV; -.
DR PDBsum; 5HLQ; -.
DR PDBsum; 5HLU; -.
DR PDBsum; 5HLX; -.
DR PDBsum; 5IKS; -.
DR PDBsum; 5ILE; -.
DR PDBsum; 5ILM; -.
DR PDBsum; 5ILP; -.
DR PDBsum; 5ILR; -.
DR PDBsum; 5JOM; -.
DR PDBsum; 5KD1; -.
DR PDBsum; 5KKK; -.
DR PDBsum; 5M3S; -.
DR PDBsum; 5MBN; -.
DR PDBsum; 5O41; -.
DR PDBsum; 5OJ9; -.
DR PDBsum; 5OJA; -.
DR PDBsum; 5OJB; -.
DR PDBsum; 5OJC; -.
DR PDBsum; 5UT7; -.
DR PDBsum; 5UT8; -.
DR PDBsum; 5UT9; -.
DR PDBsum; 5UTA; -.
DR PDBsum; 5UTB; -.
DR PDBsum; 5UTC; -.
DR PDBsum; 5UTD; -.
DR PDBsum; 5VNU; -.
DR PDBsum; 5VRT; -.
DR PDBsum; 5VZN; -.
DR PDBsum; 5VZO; -.
DR PDBsum; 5VZP; -.
DR PDBsum; 5VZQ; -.
DR PDBsum; 5WJK; -.
DR PDBsum; 5XKV; -.
DR PDBsum; 5XKW; -.
DR PDBsum; 5XL0; -.
DR PDBsum; 5YCE; -.
DR PDBsum; 5YCH; -.
DR PDBsum; 5YZF; -.
DR PDBsum; 5ZEO; -.
DR PDBsum; 5ZZF; -.
DR PDBsum; 5ZZG; -.
DR PDBsum; 6CF0; -.
DR PDBsum; 6D45; -.
DR PDBsum; 6E02; -.
DR PDBsum; 6E03; -.
DR PDBsum; 6E04; -.
DR PDBsum; 6F17; -.
DR PDBsum; 6F18; -.
DR PDBsum; 6F19; -.
DR PDBsum; 6F1A; -.
DR PDBsum; 6G5A; -.
DR PDBsum; 6G5B; -.
DR PDBsum; 6G5T; -.
DR PDBsum; 6JP1; -.
DR PDBsum; 6KRC; -.
DR PDBsum; 6KRF; -.
DR PDBsum; 6M8F; -.
DR PDBsum; 6MV0; -.
DR PDBsum; 6N02; -.
DR PDBsum; 6N03; -.
DR PDBsum; 6Z4R; -.
DR PDBsum; 6Z4T; -.
DR PDBsum; 7A44; -.
DR PDBsum; 7A45; -.
DR PDBsum; 7CEN; -.
DR PDBsum; 7CEZ; -.
DR PDBsum; 7EHX; -.
DR PDBsum; 7KYR; -.
DR PDBsum; 7L3U; -.
DR PDBsum; 7L3Y; -.
DR AlphaFoldDB; P02185; -.
DR BMRB; P02185; -.
DR PCDDB; P02185; -.
DR SMR; P02185; -.
DR STRING; 9755.ENSPCTP00005016290; -.
DR PeptideAtlas; P02185; -.
DR Ensembl; ENSPCTT00005017972; ENSPCTP00005016290; ENSPCTG00005011582.
DR GeneID; 102975021; -.
DR KEGG; pcad:102975021; -.
DR CTD; 4151; -.
DR OrthoDB; 1405713at2759; -.
DR EvolutionaryTrace; P02185; -.
DR Proteomes; UP000248484; Unplaced.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR DisProt; DP00303; -.
DR InterPro; IPR000971; Globin.
DR InterPro; IPR009050; Globin-like_sf.
DR InterPro; IPR002335; Myoglobin.
DR PANTHER; PTHR47132; PTHR47132; 1.
DR Pfam; PF00042; Globin; 1.
DR PRINTS; PR00613; MYOGLOBIN.
DR SUPFAM; SSF46458; SSF46458; 1.
DR PROSITE; PS01033; GLOBIN; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Direct protein sequencing; Heme; Iron; Metal-binding;
KW Muscle protein; Oxygen transport; Phosphoprotein; Reference proteome;
KW Transport.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000269|Ref.2"
FT CHAIN 2..154
FT /note="Myoglobin"
FT /id="PRO_0000053335"
FT BINDING 65
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="distal binding residue"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00238,
FT ECO:0000269|PubMed:845959"
FT BINDING 94
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="proximal binding residue"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00238,
FT ECO:0000269|PubMed:845959"
FT MOD_RES 4
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9QZ76"
FT MOD_RES 68
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:P04247"
FT VARIANT 122
FT /note="G -> A (in metmyoglobin)"
FT CONFLICT 123
FT /note="D -> N (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT HELIX 5..18
FT /evidence="ECO:0007829|PDB:5YCE"
FT HELIX 19..21
FT /evidence="ECO:0007829|PDB:1A6M"
FT HELIX 22..36
FT /evidence="ECO:0007829|PDB:5YCE"
FT HELIX 38..42
FT /evidence="ECO:0007829|PDB:5YCE"
FT TURN 45..49
FT /evidence="ECO:0007829|PDB:5YCE"
FT HELIX 53..57
FT /evidence="ECO:0007829|PDB:5YCE"
FT HELIX 60..77
FT /evidence="ECO:0007829|PDB:5YCE"
FT TURN 78..81
FT /evidence="ECO:0007829|PDB:5YCE"
FT HELIX 84..96
FT /evidence="ECO:0007829|PDB:5YCE"
FT TURN 97..99
FT /evidence="ECO:0007829|PDB:1MYF"
FT HELIX 102..119
FT /evidence="ECO:0007829|PDB:5YCE"
FT HELIX 121..123
FT /evidence="ECO:0007829|PDB:1A6M"
FT HELIX 126..149
FT /evidence="ECO:0007829|PDB:5YCE"
SQ SEQUENCE 154 AA; 17331 MW; FD1D85814263E1A8 CRC64;
MVLSEGEWQL VLHVWAKVEA DVAGHGQDIL IRLFKSHPET LEKFDRFKHL KTEAEMKASE
DLKKHGVTVL TALGAILKKK GHHEAELKPL AQSHATKHKI PIKYLEFISE AIIHVLHSRH
PGDFGADAQG AMNKALELFR KDIAAKYKEL GYQG