ID   MYG_VARVA               Reviewed;         154 AA.
AC   P02203;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Myoglobin;
GN   Name=MB;
OS   Varanus varius (Lace monitor).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Anguimorpha; Paleoanguimorpha; Varanoidea; Varanidae; Varanus.
OX   NCBI_TaxID=8559;
RN   [1]
RP   PROTEIN SEQUENCE OF 2-154.
RX   PubMed=6260792; DOI=10.1016/s0021-9258(19)69434-2;
RA   Maeda N., Fitch W.M.;
RT   "Amino acid sequence of a myoglobin from lace monitor lizard, Varanus
RT   varius, and its evolutionary implications.";
RL   J. Biol. Chem. 256:4301-4309(1981).
CC   -!- FUNCTION: Serves as a reserve supply of oxygen and facilitates the
CC       movement of oxygen within muscles.
CC   -!- SIMILARITY: Belongs to the globin family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00238}.
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DR   PIR; A02524; MYLZM.
DR   AlphaFoldDB; P02203; -.
DR   SMR; P02203; -.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019825; F:oxygen binding; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   InterPro; IPR000971; Globin.
DR   InterPro; IPR009050; Globin-like_sf.
DR   InterPro; IPR002335; Myoglobin.
DR   PANTHER; PTHR47132; PTHR47132; 1.
DR   Pfam; PF00042; Globin; 1.
DR   PRINTS; PR00613; MYOGLOBIN.
DR   SUPFAM; SSF46458; SSF46458; 1.
DR   PROSITE; PS01033; GLOBIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Heme; Iron; Metal-binding; Muscle protein;
KW   Oxygen transport; Transport.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000269|PubMed:6260792"
FT   CHAIN           2..154
FT                   /note="Myoglobin"
FT                   /id="PRO_0000053383"
FT   BINDING         65
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="distal binding residue"
FT   BINDING         94
FT                   /ligand="heme b"
FT                   /ligand_id="ChEBI:CHEBI:60344"
FT                   /ligand_part="Fe"
FT                   /ligand_part_id="ChEBI:CHEBI:18248"
FT                   /note="proximal binding residue"
SQ   SEQUENCE   154 AA;  17566 MW;  79EA3549C375B14C CRC64;
     MGLSDEEWKK VVDIWGKVEP DLPSHGQEVI IRMFQNHPET QDRFAKFKNL KTLDEMKNSE
     DLKKHGTTVL TALGRILKQK GHHEAEIAPL AQTHANTHKI PIKYLEFICE VIVGVIAEKH
     SADFGADSQE AMRKALELFR NDMASRYKEL GFQG