ID   A15_VACCA               Reviewed;          94 AA.
AC   P68717; Q76ZQ2;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   29-SEP-2021, entry version 39.
DE   RecName: Full=Core protein A15;
GN   OrderedLocusNames=MVA126L, ACAM3000_MVA_126;
OS   Vaccinia virus (strain Ankara) (VACV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=126794;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9601507; DOI=10.1006/viro.1998.9123;
RA   Antoine G., Scheiflinger F., Dorner F., Falkner F.G.;
RT   "The complete genomic sequence of the modified vaccinia Ankara strain:
RT   comparison with other orthopoxviruses.";
RL   Virology 244:365-396(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate Acambis 3000;
RA   Esposito J.J., Frace M., Sammons S.A., Olsen-Rasmussen M.S., Osborne J.,
RA   Khristova M., Wohlhueter R.M.;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Late protein which is a part of a large complex required for
CC       early virion morphogenesis. This complex participates in the formation
CC       of virosomes and the incorporation of virosomal contents into nascent
CC       immature virions. A15 is required for the stability and kinase activity
CC       of F10 (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Part of a complex composed of A30, G7, F10 kinase, A15, D2,
CC       D3, and J1. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Virion.
CC       Note=Localizes in cytoplasmic virus factories and present in the virion
CC       core. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A15 family. {ECO:0000305}.
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DR   EMBL; U94848; AAB96466.1; -; Genomic_DNA.
DR   EMBL; AY603355; AAT10525.1; -; Genomic_DNA.
DR   RefSeq; YP_233017.1; NC_006998.1.
DR   DNASU; 3707533; -.
DR   GeneID; 3707533; -.
DR   KEGG; vg:3707533; -.
DR   Proteomes; UP000159908; Genome.
DR   Proteomes; UP000172909; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008445; A15.
DR   Pfam; PF05846; Chordopox_A15; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Late protein; Virion.
FT   CHAIN           1..94
FT                   /note="Core protein A15"
FT                   /id="PRO_0000099245"
SQ   SEQUENCE   94 AA;  10951 MW;  70FCE23281A519F3 CRC64;
     MFVDDNSLII YSTWPSTLSD SSGRVIVMPD NRSFTFKEGF KLDESIKSIL LVNPSSIDLL
     KIRVYKHRIK WMGDIFVLFE QENIPPPFRL VNDK