MYMY_MYTED
ID MYMY_MYTED Reviewed; 33 AA.
AC P81614;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 41.
DE RecName: Full=Mytimycin;
DE Flags: Fragment;
OS Mytilus edulis (Blue mussel).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC Mytilus.
OX NCBI_TaxID=6550;
RN [1]
RP PROTEIN SEQUENCE, CHARACTERIZATION, AND MASS SPECTROMETRY.
RC TISSUE=Blood;
RX PubMed=8702979; DOI=10.1074/jbc.271.36.21808;
RA Charlet M., Chernysh S., Philippe H., Hetru C., Hoffman J.A., Bulet P.;
RT "Innate immunity. Isolation of several cysteine-rich antimicrobial peptides
RT from the blood of a mollusc, Mytilus edulis.";
RL J. Biol. Chem. 271:21808-21813(1996).
CC -!- FUNCTION: Has antifungal activity against N.crassa and F.culmorum.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- MASS SPECTROMETRY: Mass=6233.5; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:8702979};
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DR AlphaFoldDB; P81614; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Antibiotic; Antimicrobial; Direct protein sequencing; Fungicide; Secreted.
FT CHAIN 1..>33
FT /note="Mytimycin"
FT /id="PRO_0000127115"
FT NON_TER 33
SQ SEQUENCE 33 AA; 3854 MW; 8D9A8E13C00F2A9C CRC64;
DCCRKPFRKH CWDCTAGTPY YGYSTRNIFG CTC
