MYNA_MYTGA
ID MYNA_MYTGA Reviewed; 96 AA.
AC P82103;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 55.
DE RecName: Full=Myticin-A;
DE Flags: Precursor;
OS Mytilus galloprovincialis (Mediterranean mussel).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC Mytilus.
OX NCBI_TaxID=29158;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 21-56, AND MASS
RP SPECTROMETRY.
RC TISSUE=Hemocyte, and Plasma;
RX PubMed=10491159; DOI=10.1046/j.1432-1327.1999.00654.x;
RA Mitta G., Hubert F., Noel T., Roch P.;
RT "Myticin, a novel cysteine-rich antimicrobial peptide isolated from
RT hemocytes and plasma of the mussel Mytilus galloprovincialis.";
RL Eur. J. Biochem. 265:71-78(1999).
CC -!- FUNCTION: Bacteriolytic activity against Gram-positive bacteria
CC M.luteus, B.megaterium and A.viridans.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Hemocytes.
CC -!- PTM: Contains four disulfide bonds.
CC -!- MASS SPECTROMETRY: Mass=4437.45; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:10491159};
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DR EMBL; AF162334; AAD47638.1; -; mRNA.
DR AlphaFoldDB; P82103; -.
DR PRIDE; P82103; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR InterPro; IPR019631; Myticin_preproprotein.
DR Pfam; PF10690; Myticin-prepro; 1.
PE 1: Evidence at protein level;
KW Antibiotic; Antimicrobial; Direct protein sequencing; Disulfide bond;
KW Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000269|PubMed:10491159"
FT PEPTIDE 21..60
FT /note="Myticin-A"
FT /id="PRO_0000004994"
FT PROPEP 61..96
FT /note="Removed in mature form"
FT /id="PRO_0000004995"
SQ SEQUENCE 96 AA; 10556 MW; 0C7B1CC353E5C2B0 CRC64;
MKATILLAVL VAVFVAGTEA HSHACTSYWC GKFCGTASCT HYLCRVLHPG KMCACVHCSR
VNNPFRVNQV AKSINDLDYT PIMKSMENLD NGMDML