ID   MYNB_MYTGA              Reviewed;          96 AA.
AC   P82102;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Myticin-B;
DE   Flags: Precursor;
OS   Mytilus galloprovincialis (Mediterranean mussel).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Mytilida; Mytiloidea; Mytilidae; Mytilinae;
OC   Mytilus.
OX   NCBI_TaxID=29158;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 21-27, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=Hemocyte;
RX   PubMed=10491159; DOI=10.1046/j.1432-1327.1999.00654.x;
RA   Mitta G., Hubert F., Noel T., Roch P.;
RT   "Myticin, a novel cysteine-rich antimicrobial peptide isolated from
RT   hemocytes and plasma of the mussel Mytilus galloprovincialis.";
RL   Eur. J. Biochem. 265:71-78(1999).
CC   -!- FUNCTION: Bacteriolytic activity against Gram-positive bacteria
CC       M.luteus, B.megaterium and A.viridans and Gram-negative bacteria E.coli
CC       D31. Possesses antifungal activity against F.oxysporum.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Hemocytes.
CC   -!- PTM: Contains four disulfide bonds.
CC   -!- MASS SPECTROMETRY: Mass=4563.45; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:10491159};
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DR   EMBL; AF162335; AAD47639.1; -; mRNA.
DR   AlphaFoldDB; P82102; -.
DR   PhylomeDB; P82102; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR019631; Myticin_preproprotein.
DR   Pfam; PF10690; Myticin-prepro; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Disulfide bond;
KW   Fungicide; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000269|PubMed:10491159"
FT   PEPTIDE         21..60
FT                   /note="Myticin-B"
FT                   /id="PRO_0000004996"
FT   PROPEP          61..96
FT                   /note="Removed in mature form"
FT                   /id="PRO_0000004997"
SQ   SEQUENCE   96 AA;  10654 MW;  FB084F33D10E9232 CRC64;
     MKATMLLAVV VAVFVAGTEA HPHVCTSYYC SKFCGTAGCT RYGCRNLHRG KLCFCLHCSR
     VKFPFGATQD AKSMNELEYT PIMKSMENLD NGMDML