ID   MYNN_BOVIN              Reviewed;         581 AA.
AC   Q3B7N9; Q7YS83;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Myoneurin;
GN   Name=MYNN;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 114-312.
RC   TISSUE=Lung;
RX   PubMed=10873615; DOI=10.1006/bbrc.2000.2862;
RA   Alliel P.M., Seddiqi N., Goudou D., Cifuentes-Diaz C., Romero N.,
RA   Velasco E., Rieger F., Perin J.-P.;
RT   "Myoneurin, a novel member of the BTB/POZ-zinc finger family highly
RT   expressed in human muscle.";
RL   Biochem. Biophys. Res. Commun. 273:385-391(2000).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000305}.
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DR   EMBL; BC107525; AAI07526.1; -; mRNA.
DR   EMBL; AY290824; AAP42826.1; -; Genomic_DNA.
DR   RefSeq; NP_001030501.1; NM_001035424.2.
DR   RefSeq; XP_005201752.1; XM_005201695.3.
DR   AlphaFoldDB; Q3B7N9; -.
DR   SMR; Q3B7N9; -.
DR   STRING; 9913.ENSBTAP00000042339; -.
DR   PaxDb; Q3B7N9; -.
DR   PRIDE; Q3B7N9; -.
DR   Ensembl; ENSBTAT00000044888; ENSBTAP00000042339; ENSBTAG00000013142.
DR   GeneID; 539376; -.
DR   KEGG; bta:539376; -.
DR   CTD; 55892; -.
DR   VEuPathDB; HostDB:ENSBTAG00000013142; -.
DR   VGNC; VGNC:53589; MYNN.
DR   eggNOG; KOG1721; Eukaryota.
DR   GeneTree; ENSGT00940000167902; -.
DR   HOGENOM; CLU_022540_1_0_1; -.
DR   InParanoid; Q3B7N9; -.
DR   OMA; TNCDAKF; -.
DR   OrthoDB; 1318335at2759; -.
DR   TreeFam; TF330787; -.
DR   Proteomes; UP000009136; Chromosome 1.
DR   Bgee; ENSBTAG00000013142; Expressed in neutrophil and 108 other tissues.
DR   GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF00096; zf-C2H2; 5.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00355; ZnF_C2H2; 7.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   SUPFAM; SSF57667; SSF57667; 4.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 7.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome;
KW   Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..581
FT                   /note="Myoneurin"
FT                   /id="PRO_0000248216"
FT   DOMAIN          24..89
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   ZN_FING         301..323
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         329..351
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         357..380
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         386..408
FT                   /note="C2H2-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         414..436
FT                   /note="C2H2-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         442..464
FT                   /note="C2H2-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         470..493
FT                   /note="C2H2-type 7"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          167..193
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           174..190
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOTIF           256..261
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOD_RES         288
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9NPC7"
FT   CONFLICT        166..167
FT                   /note="NP -> KV (in Ref. 2; AAP42826)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   581 AA;  65412 MW;  7631CDCB58830ED3 CRC64;
     MQYSHHCEHL LERLNKQREA GFLCDCTIVI GEFQFKAHRN VLASFSEYFG AIYRSTSENN
     VFLDQSQVKA DGFQKLLEFI YTGTLNLDSW NVKEIHQAAD YLKVEEVVTK CKIKMEDFAF
     IANPSSTEIS SITGNIELNQ QTCLLTLRDY NSREKSEVST DLVQANPKQG ALAKKSSQTK
     KKKKAFNSQK TGQNKTVQYP SDILENASVE LFLDANKLST PIIEQVAQRS NSELELTSVV
     ENTFPAQDIV QTVTVKRKRG KSQPNCALKE HSMSNIASVK NSYELESSGE ELDQRYSKAK
     PMCNTCGKVF SEASSLRRHM RIHKGVKPYV CHLCGKAFTQ CNQLKTHVRT HTGEKPYKCE
     LCDKGFAQKC QLVFHSRMHH GEEKPYKCDV CNLQFATSSN LKIHARKHSG EKPYVCDRCG
     QRFAQASTLT YHVRRHTGEK PYVCDTCGKA FAVSSSLITH SRKHTGERPF ICELCGNSYT
     DIKNLKKHKT KVHSGADKIL DSSIEDHPLN EQDSIQKSPL SETLDVKPSD VTLPLTLPLG
     AEDHHLLLPV ADSQPPAPDA LLRPAANGYS EPQLIFLQQL Y