ID   A15_VACCW               Reviewed;          94 AA.
AC   P68718; Q76ZQ2;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   29-SEP-2021, entry version 36.
DE   RecName: Full=Core protein A15;
GN   OrderedLocusNames=VACWR135;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   IDENTIFICATION IN COMPLEX WITH A30; G7; F10; D2; D3 AND J1, FUNCTION,
RP   INDUCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=15567438; DOI=10.1016/j.virol.2004.10.008;
RA   Szajner P., Jaffe H., Weisberg A.S., Moss B.;
RT   "A complex of seven vaccinia virus proteins conserved in all
RT   chordopoxviruses is required for the association of membranes and viroplasm
RT   to form immature virions.";
RL   Virology 330:447-459(2004).
CC   -!- FUNCTION: Late protein which is a part of a large complex required for
CC       early virion morphogenesis. This complex participates in the formation
CC       of virosomes and the incorporation of virosomal contents into nascent
CC       immature virions. A15 is required for the stability and kinase activity
CC       of F10. {ECO:0000269|PubMed:15567438}.
CC   -!- SUBUNIT: Part of a complex composed of A30, G7, F10 kinase, A15, D2,
CC       D3, and J1. {ECO:0000269|PubMed:15567438}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000305|PubMed:15567438}.
CC       Virion {ECO:0000269|PubMed:15567438}. Note=Localizes in cytoplasmic
CC       virus factories and present in the virion core. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the chordopoxvirinae A15 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY243312; AAO89414.1; -; Genomic_DNA.
DR   RefSeq; YP_233017.1; NC_006998.1.
DR   DNASU; 3707533; -.
DR   GeneID; 3707533; -.
DR   KEGG; vg:3707533; -.
DR   Proteomes; UP000000344; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008445; A15.
DR   Pfam; PF05846; Chordopox_A15; 1.
PE   2: Evidence at transcript level;
KW   Host cytoplasm; Late protein; Reference proteome; Virion.
FT   CHAIN           1..94
FT                   /note="Core protein A15"
FT                   /id="PRO_0000099247"
SQ   SEQUENCE   94 AA;  10951 MW;  70FCE23281A519F3 CRC64;
     MFVDDNSLII YSTWPSTLSD SSGRVIVMPD NRSFTFKEGF KLDESIKSIL LVNPSSIDLL
     KIRVYKHRIK WMGDIFVLFE QENIPPPFRL VNDK